A D Harding

University of Missouri, Columbia, MO, USA

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Publications (3)3.21 Total impact

  • Article: Axillopopliteal bypass for limb salvage.
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    ABSTRACT: Forty-one axillopopliteal bypass grafts have been placed in 30 patients for limb salvage in the past 12 years. The mean patient age was 65.6 years; 8 were women; 19 smoked; and six had diabetes. Sixteen grafts were straight axillopopliteal bypass grafts, and 25 were sequential axillopopliteal bypass grafts. Cumulative life-table primary patency rates at 1, 2, and 3 years were 70%, 56%, and 43%, respectively; secondary patency rates were 73%, 57%, and 50%, respectively. Corresponding limb salvage rates were 86%, 69%, and 69%, respectively. Ringed polytetrafluoroethylene (PTFE) graft patency at 3 years was 61% versus 40% for unsupported PTFE grafts (p = 0.35). Ringed PTFE axillofemoral grafts with sequential femoropopliteal saphenous vein grafts had a 3-year patency of 67%. Graft patency was restored in 25% of occluded grafts by thrombectomy and in 80% of occluded grafts by thrombectomy with graft revision (p = 0.21). Cumulative 3-year patient survival was 48%. The 30-day operative mortality rate was 20%; patients operated on for graft infection had a 30-day operative mortality rate of 36%. The data support the use of axillopopliteal bypass for limb salvage when standard revascularization techniques are contraindicated. Long-term patency is enhanced by use of externally supported PTFE and sequential femoropopliteal saphenous vein.
    Journal of Vascular Surgery 06/1992; 15(5):817-22. · 3.21 Impact Factor
  • Article: Total parathyroidectomy and autotransplantation in hyperplasia of the parathyroid gland.
    A D Harding, W K Nichols, F L Mitchell
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    ABSTRACT: Hyperparathyroidism caused by multiple-gland hyperplasia has traditionally been treated by subtotal parathyroidectomy. Excellent results have been reported by some, particularly in primary hyperparathyroidism, but other have reported a significant incidence of recurrent hyperparathyroidism. Since 1979, we have chosen to avoid the possibility of remedial exploration of the neck and its attendant risks by treating all patients with primary and secondary hyperplasia with total parathyroidectomy and heterotopic autotransplantation. A total of 20 patients were studied. There were no failures of grafts and no operative complications. We conclude that this procedure is a reliable and safe alternative in the treatment of primary or secondary hyperplasia of the parathyroid gland.
    Surgery, gynecology & obstetrics 11/1990; 171(4):288-90.
  • Article: Late occurrence of aortoenteric fistula. After removal of a prosthetic graft.
    A D Harding, W K Nichols
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    ABSTRACT: Aortoenteric fistula is an uncommon but devastating complication of aortic surgery. The authors present a case of aortoenteric fistula occurring several years after resection of an aortic prosthesis that had not previously been involved in fistula formation. The pathophysiology and clinical evaluation of aortoenteric graft fistula are discussed.
    Missouri medicine 11/1989; 86(10):696-8.