Publications (3)6.36 Total impact

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    ABSTRACT: In the article the authors evaluate the portable insulin pump, a prototype designed at the Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences, and also Promedos E1 pump produced by Siemens in the therapy of patients with diabetes type 1 brittle. Two patients underwent therapy by means of continuous intravenous insulin infusions (CDWI) for two months, two other patients--(CPWI) for about five years. The authors made an evaluation of the two methods by counting mean blood glucose, value M according to Schlichtkrull and determining the level of glycosylated haemoglobin. By continuous infusions of insulin, the authors achieved better diabetes control than with the previous conventional therapy.
    Polskie archiwum medycyny wewnȩtrznej 05/1989; 81(4):223-30. · 2.12 Impact Factor
  • J Krzymień · E Szymerska · M Bak · M Regulski · M Tracz ·
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    ABSTRACT: The authors evaluated the effectiveness of treatment by means of constant subcutaneous insulin infusions (CPWI) in patients with diabetes staying in hospital. The infusions were made by means of portable insulin pumps (Microjet Bolus 1, Microjet Bolus 2 and Promedos E 1). The therapy was applied in a group of 15 patients with diabetes admitted to hospital because of symptoms of uncontrolled diabetes, among them 3 patients with diabetes freshly diagnosed. After 2-3 days of infusions 12 patients had glycaemia level approached to the physiological level. Only in one case of diabetes with significant resistance to insulin, the physicians were not able to control the diabetes. After 4-9 days of CPWI, patients who had been given conventional insulin injection had their insulin day demand reduced by 11-33%. In 4 cases the insulin demand had been established by means of Biostator GCIIS, after the introduction of the pumps the demand decreased by 40 +/- 5%, when the open loop system was applied. The above results suggest that the use of constant subcutaneous insulin infusion by means of a dosimeter may be recommended as a method of determining day demand for insulin, significantly shortening hospitalization period in patients with uncontrolled diabetes.
    Polskie archiwum medycyny wewnȩtrznej 05/1989; 81(4):214-22. · 2.12 Impact Factor
  • J Krzymień · E Szymerska · M Tracz · M Regulski · M Jasik ·
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    ABSTRACT: The study was aimed at elucidation of the effect of insulin-sensitivity on the occurring of the dawn phenomenon. Diabetic patients were investigated in whom the fasting glycaemia was often higher than 17 mmol/l (300 mg%). In all patients the euglycaemic state was maintained by a continuous i.v. infusion of insulin using a micropump and a changing infusion of glucose using Biostator. A slight increase in the insulin-sensitivity was seen in the early morning in 3 patients in whom the glucose consumption during the constant insulin infusion was 4 mg/min/kg b.w. Among 7 patients with lower glucose consumption in 6 a markedly low insulin-sensitivity was seen at down. The investigations allow to assume that the dawn phenomenon occurs mainly in patients with uncompensated diabetes which induces changes in insulin-sensitivity.
    Polskie archiwum medycyny wewnȩtrznej 04/1989; 81(3):176-82. · 2.12 Impact Factor