-
[show abstract]
[hide abstract]
ABSTRACT: To establish the anti-platelet or aspirin like effects of flavonoid rich food (chocolate).
This was a non-randomized quasi experimental study in which, 65 healthy adult volunteers, 27 males and 38 females, participated. The subjects included were healthy, non-smoking adults. Health of subjects was evaluated by a questionnaire for which a written informed consent was taken prior to admission in the study. Research protocol was approved by the college's, "Research and Ethical committee". Division of subjects into two groups, a control group which consumed 100 mgs of oral aspirin and an interventional group consuming 100 mgs oral aspirin and 18.75 gms of dark chocolate (flavonoid rich), was carried out. The Bleeding time estimation for both the groups was done by "Duke Method" of bleeding time estimation.
Data was analyzed by SPSS 15.0. First, a bivariate analysis was done by comparing both the pre-test groups i.e. before consumption of aspirin and also before consumption of chocolate and aspirin together through independent t-test Later, regression analysis was also done. Bivariate analysis compared both the control and interventional groups. After comparing pre-test groups a p-value of 0.798 was obtained and after comparing post test groups a p-value of 0.006 was determined. Regression analysis yeilded an R-square of 0.25.
Chocolate has a significant role in augmenting the anti-platelet effects of aspirin.
Journal of the Pakistan Medical Association 03/2011; 61(3):304-7.
-
[show abstract]
[hide abstract]
ABSTRACT: Objective: To establish the anti-platelet or aspirin like effects of flavonoid rich food (chocolate). Methods: This was a non-randomized quasi experimental study in which, 65 healthy adult volunteers, 27 males and 38 females, participated. The subjects included were healthy, non-smoking adults. Health of subjects was evaluated by a questionnaire for which a written informed consent was taken prior to admission in the study. Research protocol was approved by the college's, "Research and Ethical committee". Division of subjects into two groups, a control group which consumed 100mgs of oral aspirin and an interventional group consuming 100mgs oral aspirin and 18.75gms of dark chocolate (flavonoid rich), was carried out. The Bleeding time estimation for both the groups was done by "Duke Method" of bleeding time estimation. Results: Data was analyzed by SPSS 15.0. First, a bivariate analysis was done by comparing both the pre-test groups i.e. before consumption of aspirin and also before consumption of chocolate and aspirin together through independent t-test Later, regression analysis was also done. Bivariate analysis compared both the control and interventional groups. After comparing pre-test groups a p-value of 0.798 was obtained and after comparing post test groups a p-value of 0.006 was determined. Regression analysis yeilded an R-square of 0.25. Conclusion: Chocolate has a significant role in augmenting the anti-platelet effects of aspirin. Keywords: Chocolate, Anti-platelet, Aspirin (JPMA 61:304; 2011).
Journal of the Pakistan Medical Association 03/2011;
-
[show abstract]
[hide abstract]
ABSTRACT: Objective: To establish the anti-platelet or aspirin like effects of flavonoid rich food (chocolate). Methods: This was a non-randomized quasi experimental study in which, 65 healthy adult volunteers, 27 males and 38 females, participated. The subjects included were healthy, non-smoking adults. Health of subjects was evaluated by a questionnaire for which a written informed consent was taken prior to admission in the study. Research protocol was approved by the college's, "Research and Ethical committee". Division of subjects into two groups, a control group which consumed 100mgs of oral aspirin and an interventional group consuming 100mgs oral aspirin and 18.75gms of dark chocolate (flavonoid rich), was carried out. The Bleeding time estimation for both the groups was done by "Duke Method" of bleeding time estimation. Results: Data was analyzed by SPSS 15.0. First, a bivariate analysis was done by comparing both the pre-test groups i.e. before consumption of aspirin and also before consumption of chocolate and aspirin together through independent t-test Later, regression analysis was also done. Bivariate analysis compared both the control and interventional groups. After comparing pre-test groups a p-value of 0.798 was obtained and after comparing post test groups a p-value of 0.006 was determined. Regression analysis yeilded an R-square of 0.25. Conclusion: Chocolate has a significant role in augmenting the anti-platelet effects of aspirin.
-
[show abstract]
[hide abstract]
ABSTRACT: Globally, over the last two decades, medical education and its learning strategies are being made more prone to problem-solving in order to produce better clinicians. The medical curriculum has not changed in Pakistan since its inception and that is reflected in the form of inadequacies in health delivery system. There is a dire need of creating relevance between medical education/training and medical practice in order to introduce an effective health care system.
This study is particularly aimed at evaluating the effect of problem-based learning (PBL) in a group of students accustomed to conventional teaching and to assess any change in students attitudes/learning abilities after repeated PBL interventions.
An interventional study.
Response of 32 students of fourth year MBBS of Karachi Medical and Dental College was recorded against two PBL exercises in September 2002.
A significant change in the study trend and analytical ability (p < 003) was shown in the two PBL sessions. The students who liked PBL were 33% more prone to practice group-study (OR = 1.33 and 95% CI=1.28, 1.39) than those who preferred other modalities of teaching. The final professional grades of these students were significantly higher than those in the previous years (p < 0.000).
A strong association between liking for PBL and group study was found and the analytical performance and thought process of students were significantly improved after the second PBL session.
Journal of the College of Physicians and Surgeons--Pakistan: JCPSP 08/2003; 13(7):378-81. · 0.34 Impact Factor
