Ekta Gupta

Publications (13)24.65 Total impact

• Article: Selective endobronchial intubation in a child using a rigid bronchoscope.

  Ekta Gupta, Nishant Kumar, Ronald Bathari, Anju Romina Bhalotra, Gunjan Manchanda, Raktima Anand
  Pediatric Anesthesia 09/2011; 21(9):991-3. · 2.10 Impact Factor
• Source

  Available from: Anant Mohan

  Article: Co-infections due to leptospira, dengue and hepatitis E: a diagnostic challenge.

  Bijayini Behera, Rama Chaudhry, Anubhav Pandey, Anant Mohan, Lalit Dar, Martha M Premlatha, Ekta Gupta, Shobha Broor, Parveen Aggarwal
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  ABSTRACT: A case of mixed infection due to leptospira, dengue and hepatitis E is reported. Similar clinical presentation and simultaneous transmission of these diseases during rainy season can cause substantial misdiagnosis. Serological tests play a mainstay in diagnosis. Early detection by appropriate serological tests and institution of therapy is crucial and life saving.
  The Journal of Infection in Developing Countries 01/2010; 4(1):48-50. · 1.19 Impact Factor
• Article: Challenges in organizing trauma care systems in India.

  Amit Gupta, Ekta Gupta
  Indian Journal of Community Medicine 01/2009; 34(1):75-6.
• Article: Viral infections of the biliary tract.

  Ekta Gupta, Anita Chakravarti
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  ABSTRACT: Bacterial infections of the biliary tract are often considered to be an important cause of acute cholangitis. Viral infections of the biliary tract however, are very often mistaken as viral hepatitis. This article highlights various viral causes of common biliary tract infections. Viral cholangitis is both less common and less discussed than viral hepatitis. Hepatotropic viruses (A, B, C, and E) are generally regarded as hepatocellular pathogens, yet cholangitic manifestations are now well described in association with these diseases. Systemic viral diseases also lead to cholangitis in varying proportion to hepatitis. Human immunodeficiency virus is associated with protean hepatic complications, including cholangitis due to several causes. Other systemic viruses, most notably those of the herpes virus family, also cause hepatic disease including cholangitis and possibly ductopenia in both immunocompromised and immunocompetent patients.
  Saudi Journal of Gastroenterology 08/2008; 14(3):158-60.
• Article: Dengue fever with papilledema: a case of dengue-3 virus infection in central nervous system.

  Mohammad Tahir, Ekta Gupta, Sueba Salmani, M V Padma, M B Singh, L Dar, S Broor, S K Sharma
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  ABSTRACT: Neurological manifestations of dengue fever are rarely reported during acute illness and clinical presentation commonly observed is of acute encephalitis or one of the post-infectious immune mediated manifestations. We describe a case of dengue fever having mild encephalopathy and papilledema at presentation. Twenty-year-old female presented with fever, headache and vomiting. On examination she did not have classical signs of dengue fever and was found to have bilateral papilledema on fundus examination. Detailed work-up did not reveal any other cause of papilledema. Diagnosis of dengue fever was established by blood IgM antibody test on day 7 of illness. Retrospective analysis of CSF (drawn on day 5 of illness) by RT-PCR assay showed a characteristic band of dengue-3 virus. Papilledema was transient and subsided following symptomatic treatment. The patient recovered from acute illness and follow-up was unremarkable. Especially in dengue endemic areas, in the patients having acute febrile illness with subtle signs and symptoms suggestive of CNS involvement, dengue virus infection should also be ruled out early in the clinical course.
  Journal of Clinical Virology 10/2006; 37(1):65-7. · 3.97 Impact Factor
• Article: Nocardia pyopneumothorax in an immunocompetent patient.

  Ekta Gupta, Benu Dhawan, M M Thabah, Bimal K Das, Seema Sood, Arti Kapil
  The Indian journal of medical research 10/2006; 124(3):363-4. · 1.84 Impact Factor
• Source

  Available from: icmr.nic.in

  Article: Emerging resistance to carbapenems in a tertiary care hospital in north India.

  Ekta Gupta, Srujana Mohanty, Seema Sood, Benu Dhawan, Bimal K Das, Arti Kapil
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  ABSTRACT: Carbapenems are beta-lactam antibiotics, presently considered as most potent agents for treating multi-drug resistant Gram-negative bacilli infections. In India carbapenems available for use are meropenem and imipenem, introduced recently. Resistance to these has been reported in a few bacteria especially Pseudomonas spp. We therefore retrospectively evaluated the antibiotic susceptibility pattern to these agents amongst various clinical isolates in a tertiary care hospital in north India. In this study Gram-negative bacterial pathogens isolated from clinical samples were tested for extended spectrum beta lactamase (ESBL) production. All ESBL positive bacteria were tested for meropenem and imipenem activity pattern using NCCLS guidelines. A total of 2626 consecutively isolated Gram-negative bacteria, which tested positive for ESBL production by the double disk diffusion method, were included. The different bacteria isolated were Pseudomonas spp. 759, Acinetobacter spp. 676, Escherichia coli 569, Klebsiella spp. 343, Enterobacter spp. 150, Citrobacter spp. 57 and Proteus spp. 72. Overall resistance to meropenem was more (22.16%) than imipenem (17.32%). Maximum resistance was seen in Pseudomonas spp. M(R) 37.6 per cent, I(R) 30 per cent. In isolates from intensive care units (ICU) resistance to carbapenems was significantly higher than non-ICU patients. Resistance to meropenem and imipenem was seen in various clinical isolates of Gram-negative ESBL-positive bacteria. There is a need to alarm our clinicians for judicious use of antibiotics.
  The Indian journal of medical research 08/2006; 124(1):95-8. · 1.84 Impact Factor
• Article: Seroprevalence of rubella in pregnant women in Delhi, India.

  Ekta Gupta, Lalit Dar, Shobha Broor
  The Indian journal of medical research 07/2006; 123(6):833-5. · 1.84 Impact Factor
• Article: Oral candidiasis in HIV-infected patients and its relation to CD4 + counts: an adjunct clinical marker of HIV disease progression.

  Ekta Gupta, Madhu Vajpayee, Immaculata Xess, Pradeep Seth
  Tropical Doctor 05/2006; 36(2):127. · 0.66 Impact Factor
• Source

  Available from: Shobha Broor

  Article: Cocirculation of dengue serotypes, Delhi, India, 2003.

  Lalit Dar, Ekta Gupta, Priyanka Narang, Shobha Broor
  Emerging infectious diseases 03/2006; 12(2):352-3. · 6.17 Impact Factor
• Source

  Available from: Shobha Broor

  Article: The changing epidemiology of dengue in Delhi, India.

  Ekta Gupta, Lalit Dar, Geetanjali Kapoor, Shobha Broor
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  ABSTRACT: A major DHF outbreak occurred in Delhi in 1996. Following this another outbreak was reported in the year 2003. In the years 2004 and 2005, though no outbreak was reported, a definitely higher number of samples were received in the virology laboratory of A.I.I.M.S. from suspected cases of dengue infection. This study was designed to compare the serological and virological profiles of confirmed dengue cases in the years 2003, 2004 and 2005. Out of 1820 serum samples received from suspected cases in all three years, 811 (44.56%) were confirmed as dengue infection serologically. Out of these confirmed dengue cases maximum cases, in all three years, were seen in the age group 21-30 years. There was an increase in the number of samples received in the post monsoon period (September to November) with a peak in the second and third week of October. More samples were received from DHF cases in the year 2005 than 2004 and 2003. All four dengue serotypes were seen co-circulating in the year 2003, followed by complete predominance of dengue serotype 3 in 2005. Epidemiology of dengue is changing rapidly in Delhi. Dengue infections are seen every year thus making it an endemic disease. After co-circulation of all serotypes in 2003, now dengue serotype 3 is emerging as the predominant serotype.
  Virology Journal 02/2006; 3:92. · 2.34 Impact Factor
• Source

  Available from: Shobha Broor

  Article: Serodiagnosis of dengue during an outbreak at a tertiary care hospital in Delhi.

  Ekta Gupta, Lalit Dar, Priyanka Narang, V K Srivastava, Shobha Broor
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  ABSTRACT: Dengue, an important human arboviral infection, is endemic in many parts of India. Outbreaks are now reported quite frequently from different parts of the country. We report here findings of serological investigation of serum samples received during a recent outbreak of dengue infection in Delhi from September to November 2003. Acute phase serum samples from suspected cases of dengue infection (including dengue fever, dengue haemorrhagic fever and dengue shock syndrome) of duration 5 days, were tested for dengue specific IgM antibodies by enzyme linked immuno sorbant assay (ELISA). Of the 874 serum samples tested, 456 (52.3% ) were positive for dengue specific IgM antibodies. The maximum number of positive cases was reported in October, peaking in second and third week. Patients in the age group of 21-30 yr accounted for 34.2 per cent of positive cases. This outbreak was less severe as compared to the previous 1996 outbreak and showed a shift towards an older age group.
  The Indian journal of medical research 02/2005; 121(1):36-8. · 1.84 Impact Factor
• Article: Enhanced immunocompetent cells in chlamydial cervicitis.

  Aruna Mittal, Sangita Rastogi, B S Reddy, Saurabh Verma, Sudha Salhan, Ekta Gupta
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  ABSTRACT: To investigate changes in cell-mediated immunophenotypes by flow cytometry in endocervical secretions and peripheral blood in women with Chlamydia trachomatis infection. Fifty women attending the gynaecology outpatient department of Safdarjang Hospital, New Delhi, India, with signs and symptoms of cervicitis were enrolled. All patients underwent endocervical screening for C trachomatis (direct fluorescence antibody test [DFA]), and any coinfection with Candida (Gram stain), bacterial vaginosis (Gram stain), Neisseria gonorrhoeae (Gram stain), Trichomonas vaginalis (wet mount) and HIV (enzyme-linked immunosorbent assay) was ruled out. Flow cytometry was done to investigate changes in immunophenotypes in endocervical secretions and peripheral blood using monoclonal antibodies for surface markers (CD3, CD4, CD8, CD19, CD45 and CD83). Data were analyzed by chi2 test, while means were compared using Student's t test. C trachomatis positivity was found to be 36% (n = 18). Forty-eight patients constituted the study population since 2 patients coinfected with Candida, bacterial vaginosis and T vaginalis were excluded. A statistically significant enhancement in CD4+, CD8+ and dendritic cellular phenotypes was observed in the endocervical secretions of Chlamydia-positive patients, while B cells showed no marked difference. In the parallel study of matched peripheral blood, immunophenotypes did not show statistically significant results. Increased influx of CD4+, CD8+ and dendritic cells in the endocervix is an indication of cell-mediated immunity in response to C trachomatis infection. Local immune response in the cervical region is independent of systemic response. The mechanism by which local mucosal and systemic immune cells interact to repel or enhance susceptibility to C trachomatis infection requires further study.
  The Journal of reproductive medicine 09/2004; 49(8):671-7. · 0.87 Impact Factor