Elisa Moro

Publications (1)2.65 Total impact

• Article: Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyrrolo[1,2-c]imidazol-1-ones: a new class of Neuropeptide S antagonists.

  Fabrizio Micheli, Romano Di Fabio, Angelo Giacometti, Adelheid Roth, Elisa Moro, Giancarlo Merlo, Alfredo Paio, Emilio Merlo-Pich, Silvia Tomelleri, Federica Tonelli, Paola Zarantonello, Laura Zonzini, Anna Maria Capelli
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  ABSTRACT: A new class of selective NPS antagonist was developed starting from a commercially available product identified by screening activities. Experimental NMR observations and computational experiments allowed the discovery of a new class of derivatives. 5-Phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyrrolo[1,2-c]imidazol-1-one represents a new lead compound in the NPS antagonist field.
  Bioorganic & medicinal chemistry letters 10/2010; 20(24):7308-11. · 2.65 Impact Factor