Damian Ferrario

Hospital Italiano de Buenos Aires, Buenos Aires, Buenos Aires F.D., Argentina

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Publications (9)1.8 Total impact

  • Gastón Galimberti, Damian Ferrario
    Piel 02/2012;
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    ABSTRACT: Dermatofibrosarcoma protuberans (DFSP) is an uncommon intermediate-grade fibrohistiocytic sarcoma. It occurs most often in adults aged 20-50 years and is associated with local invasion and a high recurrence rate. Uncontrolled local disease or metastases may result in death. Treatment has involved wide excision, Mohs micrographic surgery (MMS) and other approaches. The purpose of the current study was to review our experience with MMS in the treatment of patients with DFSP over the past six years. We carried out a retrospective chart review for all patients treated with MMS at the Hospital Italiano de Buenos Aires during a six-year period to October 2009. Patient data included age and sex, site, and prior surgical treatment (if any) of the tumor and details of the Mohs procedure. Eleven patients were treated for DFSP. Four (36.4%) patients had been previously treated with a standard wide excision. Three (27.3%) of the 11 tumors were located on the back, four (36.4%) on the upper extremity, one (9.1%) on the lower extremity, and three (27.3%) on the trunk. Mean lesion size at presentation was 5.16 cm(2), and mean defect size was 12.65 cm(2), yielding a difference of 7.49 cm(2) and a ratio (defect size/lesion size) of 2.45. No tumors recurred after MMS. The recurrence potential of DFSP is directly related to the extent of resection. Mohs micrographic surgery with continuous histological margin control allows for maximum tissue preservation and low recurrence rates and is rapidly emerging as a first-line treatment modality for this condition.
    International journal of dermatology 01/2012; 51(1):89-93. · 1.18 Impact Factor
  • Piel 12/2011;
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    ABSTRACT: Basal cell carcinoma accounts for 75% of all nonmelanoma skin cancer. Although various treatment modalities are available, the most frequently used option is surgical excision. Here, we evaluate the efficacy of Mohs micrographic surgery for the treatment of basal cell carcinoma. A retrospective review of cases of basal cell carcinoma treated with Mohs micrographic surgery between October 2003 and June 2009 was performed using patient records from Hospital Italiano in Buenos Aires, Argentina. A total of 2412 basal cell carcinomas treated with Mohs micrographic surgery were identified; 50.5% were in women and 49.5% in men. The mean age of the patients was 70.7 years (range, 8-100 years). The histologic type of the tumor was solid in 65.3% of cases and in 89% of cases the tumor was located on the head or neck. Ten percent of the tumors were recurrent following previous treatment. A mean of 1.74 Mohs stages were used, with a mean of 3.81 sections. The mean size of the initial defect was 0.86 cm² and the mean final defect was 1.88 cm². The ratio of initial tumor size to final defect was estimated at 1.02. Over a mean follow-up of 32 months, there were 9 cases of tumor recurrence (0.37%). In our experience, Mohs micrographic surgery is effective for the treatment of high-risk basal cell carcinoma.
    Actas Dermo-Sifiliográficas 12/2010; 101(10):853-7.
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    ABSTRACT: IntroductionBasal cell carcinoma accounts for 75% of all nonmelanoma skin cancer. Although various treatment modalities are available, the most frequently used option is surgical excision. Here, we evaluate the efficacy of Mohs micrographic surgery for the treatment of basal cell carcinoma.
    Aorn. 01/2010; 101(10):853-857.
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    Anais Brasileiros de Dermatologia 10/2006; 81(5):473-482. · 0.62 Impact Factor
  • Piel 01/2005; 20(9):443-449.
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    ABSTRACT: El nevo epidérmico (NE) es una lesión congénita que si-gue las líneas de Blaschko y que histológicamente deriva de la epidermis. La lesión puede ser verrugosa, lisa o ape-nas palpable; pequeña o extensa; localizada o sistemati-zada; aislada o asociada a anomalías sistémicas que afec-tan fundamentalmente el esqueleto, los ojos y el sistema nervioso central; en estos casos se denominan síndrome del nevo epidérmico. Presentamos a una paciente de 9 años, argentina, que con-sultó a los 4 años de edad por presentar desde el nacimien-to un nevo epidérmico verrugoso (NEV) que sigue las lí-neas de Blaschko en hemicuerpo derecho, extendiéndose desde el cuello hasta el tobillo (Figs. 1, 2 y 3). En el flanco derecho aparece un hemangioma en fase de involución, y en la región sacra se observa una fosita pilonidal sin fondo visible. Con el fin de descartar las asociaciones extracu-táneas relacionadas con el nevo epidérmico se solicitaron estudios complementarios: en la radiografía de columna se observó escoliosis dorsolumbar con desnivel bicresti-lio. La resonancia magnética (RM) descartó la presencia de disrafismo espinal. Las evaluaciones oftalmológica, cardiológica y la ecografía abdominal no revelaron anor-malidad. En conjunto con el desarrollo de la paciente, el nevo se fue tornando más verrugoso y papilomatoso prin-cipalmente a nivel de cuello y axila provocando incomo-didad estética y dificultades en la integración social, por lo que se realizó tratamiento ablativo con láser de CO 2 en las áreas más visibles. Debido a su sospecha y tratamiento temprano la escolio-sis evolucionó en forma favorable y ahora se encuentra en tratamiento interdisciplinario con traumatología y ki-nesiología.
  • Gaston Galimberti, Damian Ferrario
    Piel