Christoph Sproll

Publications of Christoph Sproll

• Tissue expanders for soft tissue reconstruction in the head and neck area-requirements and limitations.

  Authors: Jörg Handschel, Stefanie Schultz, Rita A Depprich, Ralf Smeets, Christoph Sproll, Michelle A Ommerborn, Christian Naujoks, Norbert R Kübler, André Zimmermann

  Clinical oral investigations. 05/2012;

  OBJECTIVES: The repair of skin defects in the head and neck region still poses a significant problem for many clinicians. Tissue expansion is described as a treatment option providing good color,OBJECTIVES: The repair of skin defects in the head and neck region still poses a significant problem for many clinicians. Tissue expansion is described as a treatment option providing good color, texture, and thickness match of the expanded skin. Unfortunately, the complication rates for tissue expansion range from 0 to 48 %. Therefore, the purpose of this study was to investigate risk factors for the use of tissue expanders in head and neck reconstructions. MATERIALS AND METHODS: Forty-nine patients with skin deficits in the head and neck area underwent tissue expansion. Sixty-two implanted expanders were analyzed regarding the various complications and the success rate. RESULTS: The success rate of treated patients was 37 (75.5 %) of all 49 included patients. The most frequent cause for the skin deficit was a tumor resection near the tip of the nose followed by skin deficits resulting after craniectomy. Interestingly, a higher number of expanders and a larger volume were significantly associated with a worse outcome. There was a trend of association between larger defect size and failure, too. CONCLUSIONS: The internal tissue expansion is a suitable technique for skin reconstruction in the head and face area. Compared to distant or free flaps, it often offers a better cosmetic outcome. In very large defects (>100 cm(2)) or when more than two expanders are needed, the failure rate increases. In these cases, other treatment options are recommended. CLINICAL RELEVANCE: The internal tissue expansion is a suitable technique for skin reconstruction in the head and face area.

• Bilateral multifocal Warthin's tumors in upper neck lymph nodes. Report of a case and brief review of the literature.

  Authors: Christian Naujoks, Christoph Sproll, Daman Deep Singh, Sebastian Heikaus, Rita Depprich, Norbert R Kubler, Jorg Handschel

  Head & face medicine. 04/2012; 8(1):11.

  ABSTRACT: Cystadenolymphomas (Warthin's tumors) are the second most frequent lesions of the parotid gland. Due to their benign clinical behavior, the low rates of recurrence and malignantABSTRACT: Cystadenolymphomas (Warthin's tumors) are the second most frequent lesions of the parotid gland. Due to their benign clinical behavior, the low rates of recurrence and malignant transformation they were classified as tumor-like lesions. In addition, a polyclonal growth of the epithelial components of the tumor could be detected. Warthin's tumors occur bilateral in 7-10%, whereas a multifocal appearance is extremely rare. Even if the pathogenesis is still unclear a heterotopia of salivary tissue during embryogenesis is the most likely explanation for the origin of these tumors in the upper neck and periparotideal region. Here we present a rare case of bilateral, multifocal, extraglandular Warthin's tumors in lymph nodes of the upper neck and give a brief review of the literature. If a primary malignancy can be excluded by a careful staging procedure prior to the operation an isolated excision of the lesions of the neck is the adequate treatment.

• Role of brush biopsy and DNA cytometry for prevention, diagnosis, therapy, and followup care of oral cancer.

  Authors: Alfred Böcking, Christoph Sproll, Nikolas Stöcklein, Christian Naujoks, Rita Depprich, Norbert R Kübler, Jörg Handschel

  Journal of oncology. 01/2011; 2011:875959.

  Late diagnosis resulting in late treatment and locoregional failure after surgery are the main causes of death in patients with oral squamous cell carcinomas (SCCs). Actually, exfoliative cytology isLate diagnosis resulting in late treatment and locoregional failure after surgery are the main causes of death in patients with oral squamous cell carcinomas (SCCs). Actually, exfoliative cytology is increasingly used for early detection of oral cancer and has been the subject of intense research over the last five years. Significant advances have been made both in relation to screening and evaluation of precursor lesions. As this noninvasive procedure is well tolerated by patients, more lesions may be screened and thus more oral cancers may be found in early, curable stages. Moreover, the additional use of DNA image cytometry is a reasonable tool for the assessment of the resection margins of SCC. DNA image cytometry could help to find the appropriate treatment option for the patients. Finally, diagnostic DNA image cytometry is an accurate method and has internationally been standardized. In conclusion, DNA image cytometry has increasing impact on the prevention, diagnostic, and therapeutical considerations in head and neck SCC.