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International journal of cardiology 11/2012; · 7.08 Impact Factor
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ABSTRACT: BACKGROUND: Alcohol intake has been associated with reduced incidence of common cold symptoms in 2 European studies. However, no study has addressed the association between the frequency of alcohol intake and the incidence of common cold. This study aimed to investigate the association between the amount and frequency of alcohol drinking and the retrospective prevalence of common cold in Japanese men. METHODS: This retrospective study included men who participated in an annual health examination conducted in Sendai, Japan. The frequency of common cold episodes in the previous year was self-reported. The weekly frequency and amount of alcohol consumed, as well as the type of alcoholic drink, were reported by a brief-type self-administered diet history questionnaire. Logistic regression models were used to analyze the association between the amount and frequency of alcohol intake and the retrospective prevalence of common cold. RESULTS: Among 899 men, 83.4% of the subjects reported drinking alcohol, and 55.4% of the subjects reported having experienced at least one episode of common cold in the previous year. Compared with non-drinkers, the adjusted odds ratios (ORs) with 95% confidence intervals (CIs) for having had 1 or more episodes of common cold during the past year across categories of alcohol intake frequency of 3 or less, 4--6, and 7 days/week were 0.827 (0.541--1.266), 0.703 (0.439--1.124), and 0.621 (0.400--0.965), respectively (P for trend = 0.025); the adjusted ORs with 95% CIs for having had of 2 or more episodes of common cold across the same categories were 0.642 (0.395--1.045), 0.557 (0.319--0.973), and 0.461 (0.270--0.787), respectively (P for trend = 0.006). Compared with subjects who consumed 11.5--35.8 g of alcohol per day, the non-drinkers were significantly more likely to experience 2 or more episodes of common cold (OR, 1.843; 95% CI, 1.115--3.047). CONCLUSION: The frequency, not the amount, of alcohol intake was significantly related to lower prevalence of self-reported common cold episodes in Japanese men.
BMC Public Health 11/2012; 12(1):987. · 2.00 Impact Factor
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ABSTRACT: PURPOSE: Although previous studies suggested that higher low-fat dairy consumption lower the risk of type 2 diabetes, the mediating factors are not well understood. Higher baseline adiponectin levels are related with a lower risk of type 2 diabetes. This study evaluated whether low-fat dairy is related with adiponectin in apparently healthy adults. METHODS: We investigated a cross-sectional (n = 938) and one-year longitudinal (n = 759) relationship between low-fat and whole-/high-fat dairy (both including cow's milk and yogurt) and adiponectin. Dairy consumption was assessed with a validated food frequency questionnaire. Serum adiponectin was measured by using a specific sandwich enzyme-linked immunosorbent assay. RESULTS: In the cross-sectional analysis, the geometric means (95 % confidence intervals [95 % CIs]) of log-transformed adiponectin related with the low-fat dairy categories were 7.27 (6.80-7.77) for the lowest category, 7.67 (7.09-8.31) for the middle category, and 8.40 (7.73-9.13) for the highest category (p < 0.001) after adjustment for potential confounders (including all lifestyle factors). In the longitudinal analysis, repeated-measures ANCOVA adjusted for confounding factors showed a significant time-by-categories (categories of low-fat dairy) interaction in the change of adiponectin. In contrast, no significant relationship was found between the whole-/high-fat dairy categories and adiponectin. CONCLUSIONS: This study has shown that higher consumption of low-fat dairy, but not of whole-/high-fat dairy, is related with higher levels of adiponectin and with the change of adiponectin level at the one-year follow-up. These results suggest that the consumption of low-fat dairy may have a beneficial effect on serum adiponectin levels.
European Journal of Nutrition 05/2012; · 2.75 Impact Factor
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Haruki Momma,
Kaijun Niu,
Yoritoshi Kobayashi,
Lei Guan,
Mika Sato,
Hui Guo,
Masahiko Chujo, Atsushi Otomo,
Cui Yufei,
Hiroko Tadaura,
Tatsunori Saito,
Takefumi Mori,
Toshio Miyata,
Ryoichi Nagatomi
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ABSTRACT: Aging is associated with decreased skeletal muscle function. Increased levels of advanced glycation end products (AGEs) in skeletal muscle tissue are observed with advancing age and in diabetes. Although serum AGE level is negatively associated with grip strength in elderly people, it is unknown whether this association is present in adult males. To determine the relationship between AGE accumulation in tissue and muscle strength and power among Japanese adult men. Skin autofluorescence (AF) (a noninvasive method for measuring tissue AGEs), grip strength (n = 232), and leg extension power (n = 138) were measured in Japanese adult men [median (interquartile range) age, 46.0 (37.0, 56.0) years]. After adjustment for potential confounders, the adjusted means [95% confidence interval (CI)] for grip strength across the tertiles of skin AF were 44.5 (43.2, 45.9) kg for the lowest tertile, 42.0 (40.6, 43.3) kg for the middle tertile, and 41.7 (40.3, 43.1) kg for the highest tertile (P for trend < 0.01). Moreover, the adjusted geometric means (95% CI) of leg extension power across the tertiles of skin AF were 17.8 (16.6, 19.1) W/kg for the lowest tertile, 17.5 (16.4, 18.7) W/kg for the middle tertile, and 16.0 (14.9, 17.1) W/kg for the highest tertile (P for trend = 0.04). Among Japanese adult men, participants with higher skin AF had lower muscle strength and power, indicating a relationship between AGE accumulation and muscle strength and power. A long-term prospective study is required to clarify the causality.
Arbeitsphysiologie 12/2010; 111(7):1545-52. · 2.15 Impact Factor
