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Shinji Noda,
Yoshihide Asano,
Sho Masuda,
Takuya Miyagawa,
Miki Sugita,
Mizuho Yamamoto, Asako Kogure,
Zenshiro Tamaki,
Hiroshi Mitsui,
Toshihiko Hoashi,
Makoto Sugaya,
Shinichi Sato
Journal of the American Academy of Dermatology 08/2011; 65(2):e54-5. · 3.99 Impact Factor
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European journal of dermatology: EJD 06/2011; 21(4):623-4. · 2.53 Impact Factor
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Yohei Ichimura,
Yoshihide Asano,
Masaru Hatano,
Zenshiro Tamaki,
Tomonori Takekoshi, Asako Kogure,
Manabu Tomita,
Tomohiko Kawashima,
Miki Miyazaki,
Takashi Taniguchi,
Takehiro Takahashi,
Hiroshi Mitsui,
Makoto Sugaya,
Atsushi Yao,
Koichiro Kinugawa,
Shinichi Sato
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ABSTRACT: Systemic sclerosis (SSc) is characterized by vascular injuries, and bosentan has recently been proved to be efficacious for the prevention of new digital ulcers in SSc. We herein report a case of SSc in a patient with refractory digital ulcers and gangrene treated with bosentan. Stenosis of the ulnar artery, evaluated by magnetic resonance angiography, was attenuated by the bosentan treatment, suggesting that bosentan exerts a reverse remodeling effect against the pathological organic changes of arteries in SSc.
Modern Rheumatology 03/2011; 21(5):548-52. · 1.58 Impact Factor
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ABSTRACT: Kaposi's sarcoma (KS) is a vascular lesion of low-grade malignant potential caused by the complex interactions between geographic, genetic, environmental, and immunological factors. We recently experienced a rare case of KS associated with rheumatoid arthritis in a patient receiving corticosteroids and tacrolimus; the KS demonstrated unusually aggressive clinical behavior. We herein report the details of the clinical course and discuss the possible contribution of corticosteroids and tacrolimus to the development of aggressive KS in the present case.
Modern Rheumatology 12/2010; 21(3):309-12. · 1.58 Impact Factor