E A Schulten

Publications (37)42.42 Total impact

• Source

  Available from: washington.edu

  Article: Cheilitis granulomatosa.

  R I van der Waal, E A Schulten, M R van de Scheur, I M Wauters, T M Starink, I van der Waal
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  ABSTRACT: Cheilitis granulomatosa is a rare inflammatory disorder with unclear aetiology. It is a disorder characterized by recurrent or persistent swelling of one or both lips that may be part of the Melkersson-Rosenthal syndrome or may be a manifestation of Crohn's disease. An overview of the clinical features, histopathology, differential diagnosis, management strategies and prognosis of cheilitis granulomatosa is presented and discussed with regard to the literature.
  Journal of the European Academy of Dermatology and Venereology 12/2001; 15(6):519-23. · 2.98 Impact Factor
• Article: Paraneoplastic pemphigus caused by an epithelioid leiomyosarcoma and associated with fatal respiratory failure.

  R I van der Waal, H H Pas, H C Nousari, E A Schulten, M F Jonkman, C Nieboer, T J Stoof, T M Starink, G J Anhalt
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  ABSTRACT: A patient is described who initially presented with pemphigus vulgaris, limited to the oral cavity, and weight loss. Although the various laboratory studies pointed to the diagnosis of paraneoplastic pemphigus (PNP), the underlying neoplasm was not detected until 6 months later, when the patient developed shortness of breath and routine physical examination on admission revealed an abdominal mass, which eventually was proven to be an epithelioid leiomyosarcoma. In spite of radical excision of the tumour and intensive treatment of the dyspnoea, the patient died of respiratory failure 19 months after the PNP had been diagnosed. Early diagnosis of PNP is stressed to possibly prevent fatal pulmonary involvement.
  Oral Oncology 08/2000; 36(4):390-3. · 2.86 Impact Factor
• Article: Paraneoplastic pemphigus as the presenting symptom of a lymphoma of the tongue.

  R I van der Waal, H H Pas, G J Anhalt, E A Schulten, M F Jonkman, C Nieboer
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  ABSTRACT: A patient is described who initially presented with an acrovesicular eczema which subsequently developed into erythema multiforme with histopathological features of bullous pemphigoid. Although the various laboratory studies pointed to the diagnosis of paraneoplastic pemphigus (PNP), the underlying neoplasm was not detected until 6 months later, when the biopsies of an oral lesion showed the presence of an underlying non-Hodgkin lymphoma.
  Oral Oncology 12/1998; 34(6):567-70. · 2.86 Impact Factor
• Article: Non-Hodgkin's lymphoma of the oral cavity as the first manifestation of AIDS.

  E B Wolvius, E A Schulten, I van der Waal
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  ABSTRACT: A case of oral non-Hodgkin's lymphoma as the first manifestation of AIDS is described. The clinical presentation was that of a periodontal lesion and mental nerve paraesthesia, which may have lead to initial confusion in diagnosis and management.
  British dental journal 03/1997; 182(3):107-8. · 0.92 Impact Factor
• Article: [HIV and dentistry. Part 10. Concluding remarks].

  I van der Waal, E A Schulten, D A Sjamsoedin
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  ABSTRACT: In a summarizing report of the series 'HIV and dentistry' the most important aspects of the dental treatment of HIV-seropositive patients are dealt with, supplemented with some additional comments.
  Nederlands tijdschrift voor tandheelkunde 01/1995; 101(12):475-8.
• Article: Cyclosporin A in an adhesive base for treatment of recalcitrant oral lichen planus. An open trial.

  A B Voûte, E A Schulten, P N Langendijk, C Nieboer, I van der Waal
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  ABSTRACT: Patients with symptomatic oral lichen planus often require therapy to reduce signs and symptoms of the condition. For this purpose, corticosteroids are frequently used. In this study the effect of another immunosuppressive drug, cyclosporin A was evaluated; it was applied as a topical drug four times daily and contained 0.025% cyclosporin A. The study group was composed of nine symptomatic patients in whom the diagnosis of oral lichen planus was confirmed by histopathologic examination including immunofluorescence. All patients had unsuccessfully undergone previous treatment with topical or systemic corticosteroids. The minimum follow-up period in the present study was at least 4 months. Four patients showed partial response to treatment with respect to signs and symptoms. None of the patients had a complete remission. Five patients showed no response or even complained of an increase of signs and symptoms. No adverse side effects of the drug were recorded during follow-up. Although the number of patients has been small, the results of this study indicate that topical application of cyclosporin A (0.025%) in the treatment of recalcitrant oral lichen planus does not offer a distinct advantage over the use of topical corticosteroids.
  Oral Surgery Oral Medicine Oral Pathology 11/1994; 78(4):437-41.
• Article: [HIV and dentistry. Part 9. HIV infection and dental care].

  D A Sjamsoedin, E A Schulten, I van der Waal
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  ABSTRACT: Dental treatment of HIV-infected or AIDS patients can be safely performed in the dental office. In general, no special precautions are necessary. Only in case of severe illness a dental emergency may have to be referred to a dedicated clinic. Ideally, the dentist should have the possibility to treat his own patient in such a clinic.
  Nederlands tijdschrift voor tandheelkunde 11/1994; 101(10):392-3.
• Article: [Second primary tumors following treatment of squamous cell carcinoma of the oral cavity].

  I G van der Tol, A Jovanovic, E A Schulten, P J Kostense, N de Vries, G B Snow, I van der Waal
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  ABSTRACT: In the hospital of the Free University in Amsterdam (the Netherlands) 727 patients with primary squamous cell carcinoma of the oral cavity and lip have been studied for the incidence of second primary tumors occurring in the respiratory and upper digestive tract. Out of the 727 patients, 74 (10.2%) developed a second primary tumor in these tracts. The incidence of second primary tumors was expressed per 1.000 person-years of follow-up; 28 second primary tumors per 1.000 person-years of follow-up were seen in the respiratory and upper digestive tract. The patients ran the risk of developing a second primary tumor at a steady rate of approximately 2.8% per year during at least ten years. Furthermore, an increasing incidence of second primary tumors could be observed in case of increasing use of tobacco.
  Nederlands tijdschrift voor tandheelkunde 11/1994; 101(10):403-5.
• Article: [HIV and dentistry. Part 8. Can a dentist refuse treatment to an HIV seropositive patient?].

  D A Sjamsoedin, S Strijbos, E A Schulten, I van der Waal
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  ABSTRACT: An overview is presented of the ethical guidelines in different parts of the world on the subject of dental treatment of HIV-seropositive patients. Does a dentist ever have the right to decline treatment and will the answer to this question be influenced by the presence or absence of dental complaints? Based on several reports it is likely that some dentists refuse treatment of HIV-seropositive patients.
  Nederlands tijdschrift voor tandheelkunde 09/1994; 101(8):302-4.
• Article: [HIV and dentistry. Part 7. The HIV positive dentist or student].

  D A Sjamsoedin, E A Schulten, I van der Waal
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  ABSTRACT: What should a dentist or dental student do when he happens to be HIV-seropositive? Should he or she disclose the disease to the patients or, in case of a student, to the university? Does he has to give up his practice or perhaps not even open one? Apparently, the legal regulations differ in various parts of the world. In the Netherlands dentists are advised to take their own responsibility in this matter.
  Nederlands tijdschrift voor tandheelkunde 08/1994; 101(7):262-3.
• Article: Second respiratory and upper digestive tract cancer following oral squamous cell carcinoma.

  A Jovanovic, I G van der Tol, P J Kostense, E A Schulten, N de Vries, G B Snow, I van der Waal
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  ABSTRACT: 727 patients with squamous cell carcinoma (SCC) of the lip and oral cavity have been followed for the occurrence of second primary tumours (SPTs) in the respiratory and upper digestive tract (RUDT). 74 patients (10%) developed at least one SPT in the RUDT. The incidence of SPTs was expressed per 1000 person-years of follow-up. In our study about 28 SPTs per 1000 person-years of follow-up were seen in the RUDT. Patients were at risk for a second primary tumour, at a steady rate of approximately 2.8% per year during at least 10 years. Furthermore, patients with an index tumour in the lower part of the mouth (floor of mouth, retromolar area and lower alveolar process), which is more related to tobacco and/or alcohol, seem to be more at risk for SPTs than patients with an index tumour in the other (sub)sites of the mouth.
  European Journal of Cancer Part B Oral Oncology 08/1994; 30B(4):225-9.
• Article: [HIV and dentistry. Part 6. Mouth defects in HIV infections: guidelines for referral].

  I van der Waal, D A Sjamsoedin, E A Schulten
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  ABSTRACT: As for any oral lesion that cannot be properly diagnosed by the dentist, referral to the specialist is indicated for lesions that might be associated with or indicative of an underlying HIV infection. In most instances, there is no need to discuss the subject of HIV infection in the dental office. In the letter of referral the same information should be given as has been provided to the patient. The specialist should not withhold information for the referring dentist, even when requested by the patient to do so.
  Nederlands tijdschrift voor tandheelkunde 07/1994; 101(6):229-30.
• Article: [HIV and dentistry. Part 5. Practice hygiene].

  D A Sjamsoedin, W R Moorer, E A Schulten, I van der Waal
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  ABSTRACT: When complying a good standard hygiene protocol in the dental office the risk of cross-infection of whatever type of microorganism, including the hepatitis-B-virus and HIV, is almost eliminated.
  Nederlands tijdschrift voor tandheelkunde 06/1994; 101(5):209-12.
• Article: [HIV and dentistry. Part 4. Oral deviations in HIV infections: present classification and diagnostic criteria].

  E A Schulten, D A Sjamsoedin, I van der Waal
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  ABSTRACT: In the present classification of oral lesions associated with HIV infection a distinction is made between presumptive and definitive diagnostic criteria. The former relate to the initial clinical appearance of the lesion and the latter are often the result of special investigations. Candidiasis, hairy leukoplakia, specific forms of periodontal disease, Kaposi's sarcoma and non-Hodgkin's lymphoma are strongly associated with HIV infection. Lesions less commonly associated with HIV infection and lesions seen in HIV infection, but not indicative of the disease, are also listed.
  Nederlands tijdschrift voor tandheelkunde 05/1994; 101(4):132-5; quiz 136, 143.
• Article: [HIV and dentistry. Part 3. HIV infection: pathogenesis, epidemiology, definitions and classification].

  E A Schulten, S A Danner, D A Sjamsoedin, I van der Waal
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  ABSTRACT: The acquired immunodeficiency syndrome (AIDS) is caused by a retrovirus, the human immunodeficiency virus (HIV), that selectively deteriorates cell-mediated immunity. Consequently fatal opportunistic infections and/or malignancies occur. In this paper the pathogenesis and the epidemiology of HIV infection are described. In addition the 1993 revised classification for HIV infection and the expanded surveillance case definition for AIDS are presented.
  Nederlands tijdschrift voor tandheelkunde 04/1994; 101(3):81-5.
• Article: Risk of multiple primary tumors following oral squamous-cell carcinoma.

  A Jovanovic, I G van der Tol, E A Schulten, P J Kostense, N de Vries, G B Snow, I van der Waal
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  ABSTRACT: The follow-up of 727 patients with squamous-cell carcinoma (SCC) of the lip and oral cavity has been used for the risk analysis of multiple primary tumors (MPTs) following SCC of the lip and oral cavity. Age-, gender- and site-specific cancer-incidence rates from the general population have been applied to the appropriate persons-years of follow-up of patients with SCC of the lip and oral cavity. The study indicates that patients with a primary SCC of the lip and oral cavity have, compared with the general population, a significantly elevated risk of developing an additional cancer of the oral cavity and/or pharynx, the risk being 74.7-fold for males and 190.4-fold for females. Furthermore, a 24.6 and 45.3 times higher risk of an additional esophageal tumor was found in males and females respectively. The risk of cancer of the lung and pharynx was less elevated compared with the risk of cancer of the upper digestive tract. No elevated risks were established in organs outside the respiratory and upper digestive tract.
  International Journal of Cancer 03/1994; 56(3):320-3. · 5.44 Impact Factor
• Article: [HIV and dentistry. Part 2. Needlestick injury].

  D A Sjamsoedin, H Houweling, E A Schulten, J de Graaff, I van der Waal
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  ABSTRACT: The risk for dentists to acquire HIV infection at work is low but not neglectable. Needlestick injuries are among the most hazardous events in this respect. Prevention of these injuries will considerably reduce the risk of occupational HIV infection in dentistry.
  Nederlands tijdschrift voor tandheelkunde 03/1994; 101(2):47-9.
• Article: [HIV and dentistry. Part 1: Disclosure of HIV-seropositivity to the dentist].

  D A Sjamsoedin, E A Schulten, I van der Waal
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  ABSTRACT: For a number of reasons it is recommended to disclose one's HIV-seropositivity to the dentist. This information will enable the dentist to take extra precautions during treatment. Furthermore, extra measures may be taken with regard to prevention or early treatment of dental and oral diseases, e.g. gingivitis, candidiasis. The dentist and the other members of the dental team are supposed to obey strict confidentiality.
  Nederlands tijdschrift voor tandheelkunde 02/1994; 101(1):3-5.
• Article: Tobacco and alcohol related to the anatomical site of oral squamous cell carcinoma.

  A Jovanovic, E A Schulten, P J Kostense, G B Snow, I van der Waal
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  ABSTRACT: The aim of the present study was to evaluate the possible relationship between tobacco smoking and alcohol drinking and the anatomical sites of squamous cell carcinoma (SCC) of the lip and oral cavity. For this purpose, a case-case study has been performed in 690 patients. The study was focused on the relative risk (RR) or developing SCC at various (sub)sites, for smokers and drinkers of alcohol (divided into moderate and heavy users) relative to non-smokers and non-drinkers. Estimates of ratios of these relative risks were obtained. The relative risk associated with tobacco smoking, adjusted for the use of alcohol, appeared to be highest for SCC in the retromolar area, followed by the floor of mouth, whereas the lowest RR was found in the cheek mucosa. For alcohol drinking, adjusted for tobacco smoking, RR of SCC of the floor of mouth was significantly higher than for the tongue, whereas the RR of SCC of the cheek appeared to be lowest. Furthermore, this study suggests that the contrasts between relative risks, observed by anatomical site of oral SCC, are more pronounced for tobacco smoking than for the use of alcohol. The possible local and systemic factors responsible for these variations of susceptibility for tobacco and alcohol within the oral cavity are discussed.
  Journal of Oral Pathology and Medicine 12/1993; 22(10):459-62. · 1.63 Impact Factor
• Article: Lichen sclerosus et atrophicus involving the oral mucosa: report of two cases.

  E A Schulten, T M Starink, I van der Waal
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  ABSTRACT: Lichen sclerosus et atrophicus (LSA) is a relatively rare dermatosis of unknown etiology. The disease is clinically characterized by white, macular lesions on the skin, and is usually associated with an atrophic condition affecting the vulva and peri-anal skin. Involvement of the oral mucosa with or without concurrent genital or skin lesions has been reported only occasionally in the literature. In the present paper two new cases of oral LSA are presented, which were, in fact, the only manifestation of the disease. Furthermore, the epidemiologic, etiologic, clinical and histopathologic aspects of oral LSA are discussed.
  Journal of Oral Pathology and Medicine 10/1993; 22(8):374-7. · 1.63 Impact Factor