Agnieszka Matuszewska

Publications of Agnieszka Matuszewska

• [A case of early recognized Wegener's granulomatosis with renal involvement. Insights for early diagnosis].

  Authors: Agnieszka Matuszewska, Maria Misterska-Skóra, Piotr Wiland

  Annales Academiae Medicae Stetinensis. 01/2010; 56(1):41-4; discussion 44.

  Systemic necrotic and granulomatous vasculitis presents with vascular involvement in almost every organ, manifesting with stenosis, ischemia, infarction, or hemorrhage. The clinical picture dependsSystemic necrotic and granulomatous vasculitis presents with vascular involvement in almost every organ, manifesting with stenosis, ischemia, infarction, or hemorrhage. The clinical picture depends on the kind and size of the involved vessels and on the activity of the inflammatory process. Wegener's granulomatosis is a necrotic, granulomatous inflammation of small vessels of the upper and lower airways and kidneys. We present the case of a 25-year-old male in whom the definitive diagnosis of Wegener's granulomatosis was achieved within five weeks from onset. Among the first symptoms were microinfarcts localized in the fingertips and the nail matrix; their nature was investigated with capillaroscopy.

• [Active psoriatic arthritis during pregnancy: challenges and limitations of pharmacotherapy].

  Authors: Agnieszka Matuszewska, Maria Misterska-Skóra, Piotr Wiland

  Annales Academiae Medicae Stetinensis. 01/2010; 56 Suppl 1:45-7.

  Cases of psoriatic arthritis coexisting with pregnancy are sparse and therefore little is known about the fetal effect of medication in women with psoriatic arthritis. As a rule, drugs and dosagesCases of psoriatic arthritis coexisting with pregnancy are sparse and therefore little is known about the fetal effect of medication in women with psoriatic arthritis. As a rule, drugs and dosages are minimized in these patients. Among disease-modifying antirheumatic drugs, cyclosporine and sulphasalazine are preferred. Methotrexate and leflunomide are strictly contraindicated and must be withdrawn 3 months or 2 years, respectively, before a pregnancy is planned. Psoriatic arthritis may be treated during pregnancy with glucocorticosteroids, especially with prednisone or prednisolone. We present the case ofa 40-year-old gravida with psoriatic arthritis which exacerbated during the first trimester of pregnancy. Therapeutic implications in such cases are discussed.