Yuka Matsuo

Tokyo Women's Medical University, Edo, Tōkyō, Japan

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Publications (10)6.61 Total impact

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    ABSTRACT: OBJECTIVE: To evaluate the frequency and common locations of myocardial fat and its associated factors using coronary CT angiography (CCTA) in patients without cardiac disease. METHODS: Using CCTA findings for 298 consecutive patients without cardiac disease, we categorized the myocardium into nine locations, scored fat in those locations, and correlated the fat score with the thickness of the right ventricular (RV) free wall and factors including gender, age, and body mass index (BMI) as well as history of diabetes mellitus, hypertension (HT), and dyslipidemia. RESULTS: We observed myocardial fat in 68.5 % of patients, most commonly in the RV outflow tract (RVOT, 64.1 %), followed by the base (42.3 %) and middle (28.9 %) of the RV free wall, RV trabeculations (22.5 %), and the left ventricular apex (11.4 %). The RV free wall thickened significantly with increasing fat score. Dependent variables for myocardial fat were female gender (P < 0.0001), age ≥65 years (P = 0.0043), BMI ≥25 (P = 0.0050), and HT (P = 0.0139). CONCLUSION: Myocardial fat is a common finding on CCTA in patients without cardiac disease, is often observed in the RVOT, and is more frequent in female patients, those older than 65 years, those with BMI ≥25, and those with HT.
    Japanese journal of radiology 05/2013; · 0.73 Impact Factor
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    ABSTRACT: Left ventricular (LV) pseudoaneurysm is a serious complication of periannular extension of infective endocarditis (IE). Because pseudoaneurysm carries a high risk of rupture, its detection and evaluation are crucial for patient management and surgical planning. We report 2 cases with LV pseudoaneurysms, one near the aortic valve and the other near the mitral valve, which were caused by IE and treated successfully. In both cases, cardiac multidetector-row computed tomography enabled detection of the LV pseudoaneurysm and a detailed demonstration of its anatomic relationship with surrounding structures, which helped guide surgical planning.
    Journal of thoracic imaging 09/2011; 27(6):W165-7. · 1.42 Impact Factor
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    ABSTRACT: PURPOSE Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) is useful for diagnosis of myocardial damage in cardiac sarcoidosis (CS), however it is difficult to distinguish CS complicated with low ejection fraction (EF) and dilatation of left ventricle (LV) from idiopathic dilated cardiomyopathy (iDCM). Purpose of this study is to clarify the LGE pattern on CMR in both CS and iDCM, and to evaluate the diagnostic ability of each LGE pattern for distinguishing CS from iDCM. METHOD AND MATERIALS CMR study were performed in sixty patients (male/female = 38/22, age 26-77 years) with left ventricular (LV) ejection fraction less than 40% and LV diasttolic diameter greater than 60mm. Dilated phase of hypertrophic cardiomyopathy, ischemic heart disease, and valvular heart disease were excluded. Using Japanese Ministry of Health and Welfare (JMH) 2006 as a consensus criteria for the diagnosis of CS, subjects were divided into CS (n=16) and iDCM (n=44). Of the 16 patients with CS; eight patients were diagnosed CS on basis of JMH2006 criteria, two patients were highly suspected of CS but lack sarcoidosis findings in other organs, and six patients were suspected of CS due to basal wall septum thining and, ventricular focal LV aneurysm. According to the results of LGE on CMR, we did visual segment analysis using standard AHA 17-segments model. The LGE were assessed each segment, localization (5 patterns: endocardial, mid-wall, epicardial, transmural, and multiple), distribution (3 types: patchy, linear as within 50% of myocardial thickness and band-like as greater than 50% of myocardial thickness), and signal intensity (definitively or lightly). RESULTS Epicardial, transmural, band-like and definitively high intensity of LGE were typical characteristic findings of CS; The odds ratio in each findings were 0.054, 0.04, 0.111 and 0.06 respectively. In those typical CS findings, sensitivity was 75.0-87.5%, specificity was 68.2-88.9% and NPV was 89.2-93.8% (table). CONCLUSION The LGE pattern on CMR is useful to differentiate cardiac sarcoidosis from idiopathic dilated cardiomyopathy. CLINICAL RELEVANCE/APPLICATION Late gadlinium enhancement pattern is useful to distinguish secondary cardiomyopathy caused by cardiac sarcoidosis from in patients with left ventricular dilatation and low ejection fraction.
    Radiological Society of North America 2010 Scientific Assembly and Annual Meeting; 11/2010
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    ABSTRACT: Myocardial fat is often seen at cardiac computed tomography (CT) and magnetic resonance (MR) imaging of healthy adults and patients with myocardial diseases. Physiologic myocardial fat develops with aging and is commonly seen at CT in the anterolateral right ventricular (RV) free wall and RV outflow tract with normal or thickened RV myocardium and a normal-sized RV in elderly patients. Pathologic conditions with myocardial fat include healed myocardial infarction (MI); arrhythmogenic RV cardiomyopathy or dysplasia (ARVC); and others, such as cardiac lipoma, lipomatous hypertrophy of the interatrial septum, tuberous sclerosis complex, dilated cardiomyopathy, and cardiomyopathy with muscular dystrophy. In patients with healed MI, CT and MR imaging show fat in left ventricular myocardium that is of normal thickness or thin and follows the distribution of the coronary artery; CT often depicts fat in mostly subendocardial regions. In patients with ARVC, characteristic CT and MR imaging findings include a thin RV outflow tract and free wall caused by subepicardial fatty infiltration; fat in the RV moderator band, trabeculae, and ventricular septum; and RV enlargement and wall motion abnormality. Recognition of patient age, characteristic locations of myocardial fat, myocardial thickness, and ventricular size helps in differentiating physiologic and pathologic myocardial fat at cardiac imaging; findings of wall motion abnormality and late gadolinium enhancement at MR imaging help narrow the diagnosis.
    Radiographics 10/2010; 30(6):1587-602. · 2.79 Impact Factor
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    ABSTRACT: We report three cases with a rare anatomic variation, in which the common hepatic artery (CHA) arose from the left gastric artery. Fewer than ten cases with this anatomic variation have been published in the literature consulted. In each patient, multidetector-row CT image with 3D reformation demonstrated that the hepatic artery arises from the left gastric artery and runs through the lesser omentum. The left, middle, and right hepatic arteries derived from this artery, and no other arterial supply to the liver was seen. The course of the gastroduodenal artery was variable; it derived from the CHA, the splenic artery, or both. No variation was noted in the splenic artery and the superior mesenteric artery.
    Anatomia Clinica 04/2010; 32(7):703-5. · 0.93 Impact Factor
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    ABSTRACT: A 38-year-old woman was transferred to the hospital with lower abdominal pain. Magnetic resonance (MR) imaging revealed an irregular ovarian wall with a solid component and a fluid-fluid level in the cystic mass and the pelvic space, which was thought to be pathognomonic for the rupture of an endometrioma with a malignant ovarian tumor. Histologic examination following adnexectomy revealed a ruptured endometrioma associated with endometrioid adenocarcinoma. A fluid-fluid level in the cystic mass and pelvic space may be pathognomonic MRI feature for a rupture of either an endometrioma or an endometrioma with a malignant tumor.
    Magnetic Resonance in Medical Sciences 01/2010; 9(4):233-6. · 0.75 Impact Factor
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    ABSTRACT: PURPOSE We evaluated myocardial fat in patients without cardiac disease using ECG-gated MDCT, and we assessed associated factors. METHOD AND MATERIALS We retrospectively analyzed 100 consecutive patients (56 men, 44 women; mean age, 62.3 years; range, 25-85 years) who underwent ECG-gated non-contrast- and contrast-enhanced coronary CT at our institution between May 2007 and January 2008 and whose right ventricle (RV) could be assessed. None of these had ischemic heart disease, cardiomyopathy, severe valvular disease, congestive heart failure, or a pacemaker. We evaluated frequency, location, and degree of myocardial fat. We categorized 5 locations: RV outflow tract (RVOT), RV free wall (base, middle, and apex), RV trabeculation and moderator band, left ventricular (LV) apex, and other regions of the LV and interventricular septum. We classified degree of fatty infiltration on a 4-point scale: 0, none; 1, mild; 2, moderate; and 3, severe and calculated overall degree by adding the points of all segments. We evaluated the relationship between myocardial fat and RV free wall thickness and between overall degree and associated factors, including sex, age, body mass index (BMI﴿, diabetes mellitus, and hyperlipidemia. RESULTS Of the 100 patients, 72 (72%) had myocardial fat−frequently in the RV (RVOT 68%, basal free wall 62%, middle free wall 47%, RV trabeculations and moderator band 27%) and less often in the left ventricular (LV) apex (12%) and other regions of the LV and interventricular septum (12%). The RV free wall was identified in all patients and statistically thicker in patients with myocardial fat than those without. The overall degree of myocardial fat was statistically greater in women (P < 0.0001), patients with hyperlipidemia (P = 0.0063), and patients older than 65 years (P = 0.006). CONCLUSION Myocardial fat is a common CT finding in patients without cardiovascular disease and often observed in the RVOT and RV free wall. Myocardial fat is seen more in women, patients older than 65 years, and those with hyperlipidemia. CLINICAL RELEVANCE/APPLICATION Understanding frequency, common locations, and associated factors of myocardial fat in patients without cardiovascular disease may prevent false diagnosis of ARVC and old myocardial infarction.
    Radiological Society of North America 2009 Scientific Assembly and Annual Meeting; 11/2009
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    ABSTRACT: PURPOSE/AIM 1.To show radiological features of acute-onset lung complications of CVD 2.To show points of clinical manifestations of acute-onset lung complications of CVD; lung complication of CVD itself, infection and drug-induced lung injury. 3.To show how to integrate clinical and radiological findings to make a differential diagnosis more precise. CONTENT ORGANIZATION 1. Acute-onset lung complication of CVD; its clinical aspects 2. Imaging features of acute-onset lung involvement of CVD itself 3. Imaging and clinical features of drug-induced lung injuries used for treatment of CVD 4. Imaging and clinical features of infectious diseases in CVD patients . 5. To show how to integrate imaging findings with clinical and laboratory findings to make a dignosis more precise, because imaging findings of these conditions are sometimes nonspecific and similar. SUMMARY 1. Imaging features of acute onset lung complications of CVD are sometimes nonspecific and similar. 2.Points of clinical presentation include disease activity of CVD, drug for CVD, degree of immunodeficiency, temporal relationship between symptoms and administration of drug, prophylaxis of infection, results of bacteriologic study and levels of serum markres of infection and lung disease. 3.We show how to combine imaging findings with clinical features for precise diagnoses using flow charts.
    Radiological Society of North America 2008 Scientific Assembly and Annual Meeting;
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    ABSTRACT: PURPOSE/AIM The purpose of this exhibit is: 1. To review radiologic-pathologic correlation among cardiomyopathies 2. To discuss the utility of CT and MR in diagnosing cardiomyopathies CONTENT ORGANIZATION Primary cardiomyopathies, including hypertrophic cardiomyopathies, dilated cardiomyopathy, arrhythmogenic right ventricular (ARVC) and left ventricular non-compaction, and secondary cardiomyopathies, including sarcoidosis, amyloidosis, and Fabry’s disease, are discussed as follows. 1. Clinical features and pathogenesis 2. Histopathologic features 3. CT and MR imaging features 4. Key differential points among cardiomyopathies based on imaging features SUMMARY 1. On MR imaging, areas of late gadolinium enhancement (LGE) mostly correspond to histologic findings of myocardial fibrosis in cardiomyopathy, but technical limitations of MRI prevent demonstration by LGE of all areas of fibrosis and other abnormalities on histology. 2. MR imaging allows narrowing of differential diagnosis among cardiomyopathies based on functional and LGE findings. CT is useful to rule out coronary artery disease, to diagnose ARVC, and to find extra-cardiac abnormalities.
    Radiological Society of North America 2010 Scientific Assembly and Annual Meeting;
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    ABSTRACT: PURPOSE/AIM 1. To review common causes of myocardial fat on cardiac CT 2. To review characteristic CT findings of pathologic and non-pathologic (patients without cardiovascular disease) fat 3. To review points differentiating pathologic from non-pathologic fat on CT CONTENT ORGANIZATION  CT findings for different causes of myocardial fat – Patients without cardiovascular disease – Patients with old myocardial infarction (MI) – Patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) – Others  Key differential points between pathologic and non-pathologic myocardial fat on cardiac CT  Understanding CT findings of different causes of myocardial fat based on pathological correlation SUMMARY 1. Non-pathologic myocardial fat is common in the elderly and often observed in the right ventricular (RV) outflow tract and RV free wall. 2. Myocardial fat in ARVD/C is common in RV trabeculation and the interventricular septum. The RV myocardium in ARVD/C is usually very thin with subepicardial fatty replacement, but slightly thick with non-pathologic fat. 3. Fat in old MI is usually distinguished by its characteristic subendocardial location in coronary artery territories.
    Radiological Society of North America 2009 Scientific Assembly and Annual Meeting;