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Publications (2)3.38 Total impact

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    ABSTRACT: Films of oriented bacteriorhodopsin have been formed in polyvinyl alcohol with excellent optical quality. Images with high contrast have been impressed and erased on these films. Second-harmonic microscopy has been used to read the image on a bacteriorhodopsin-polyvinyl alcohol film without erasure. The potential of these films for molecular information storage and computation is discussed.
    Applied Optics 12/1991; 30(35):5188-96. DOI:10.1364/AO.30.005188 · 1.69 Impact Factor
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    ABSTRACT: The sign of the optoelectrical response of bacteriorhodopsin is highlighted as a means to emulate excitation and inhibition in neural computation. A classic example of a neural computation that is based on such excitation and inhibition is chosen to highlight the unique applicability of bacteriorhodopsin in highly parallel computational schemes. The classic example chosen is that of the ganglion receptive field, which is a fundamental element in retinal edge detection. Dried bacteriorhodopsin films are constructed that effectively act as receptive fields because of the sign of their photoresponse. The results on these simple bacteriorhodopsin receptive fields are extended to schemes that incorporate with greater elegance this unique ability of bacteriorhodopsin to exhibit excitation and inhibition. Experiments are presented that test some of these advanced ideas in bacteriorhodopsin parallel computation.
    Applied Optics 02/1991; 30(4):500-9. DOI:10.1364/AO.30.000500 · 1.69 Impact Factor