Xiaoming Lou

Shenzhen Center for Disease Control and Prevention, Shenzhen, Zhejiang Sheng, China

Are you Xiaoming Lou?

Claim your profile

Publications (9)7.84 Total impact

  • Article: [Exposure level and characteristics of dioxins in children living near the waste incineration power plant].
    [show abstract] [hide abstract]
    ABSTRACT: To study the internal and external dioxins exposure level of children living near the waste incineration power plant. Peripheral blood of children (90 in S, 60 in L), soils, crucians, chicken eggs were sampled in town S (1 km away from a big waste incineration power plant), as well as in town L (200 km away from S), which is the control. The contents, distribution characteristics and toxic equivalent (TEQ) of dioxins in samples were evaluated by ultra-trace detection methods. The concentrations and TEQs of dioxins in blood, soils, crucians and chicken eggs from town S were significantly higher than those in town L (P < 0.05). The dominant dioxin detected from the samples is OCDD, while the dominant TEQ contribution dioxin is 2, 3, 4, 7, 8-PeCDF. The emission of dioxins from the waste incineration power plant may increase the internal and external dioxins exposure level of children living nearby.
    Wei sheng yan jiu = Journal of hygiene research 01/2013; 42(1):87-91.
  • Article: Health risk assessment of lead for children in tinfoil manufacturing and e-waste recycling areas of Zhejiang Province, China.
    [show abstract] [hide abstract]
    ABSTRACT: Tinfoil manufacturing and electronic waste (e-waste) recycling remain rudimentary processes in Zhejing Province, China, which could account for elevated blood lead levels (BLLs) and health impacts on children. We assessed the potential health risks of lead in tinfoil manufacturing and e-waste recycling areas. 329 children in total aged 11-12 who lived in a tinfoil manufacturing area (Lanxi), an e-waste recycling area (Luqiao) and a reference area (Chun'an) were studied. Lead levels in children's blood were determined by inductively coupled plasma mass spectrometer (ICP-MS). Blood urea nitrogen (BUN), serum creatinine, serum calcium, δ-Aminolaevulinic acid (δ-ALA) and intelligence quotient (IQ) were also measured. Geometric mean of BLLs in Lanxi, Luqiao and Chun'an were 8.11 μg/dL, 6.97 μg/dL, and 2.78 μg/dL respectively, with 35.1%, 38.9% and 0% of children who had BLLs above 10 μg/dL. The BLLs in exposed areas were much higher than those in the control area. Lanxi children had higher creatinine and calcium than Chun'an children, and Luqiao children had higher δ-ALA and lower calcium than Chun'an children. No significant differences of IQ were observed between Lanxi, Luqiao and Chun'an, however a negative relationship between BLLs and IQ was shown for the study children. The results indicated that lead pollution from e-waste recycling and tinfoil processing appears to be a potential serious threat to children's health.
    Science of The Total Environment 04/2012; 426:106-12. · 3.29 Impact Factor
  • Article: [Oxidative damage and immunotoxicity effect of people who exposed to electronic waste].
    [show abstract] [hide abstract]
    ABSTRACT: To investigate the relationship between risk factors and the effects of antioxidation and immune function in adults who exposed to electronic waste( e-waste). The exposed group was chosen from the people who lived in the e-waste disposing areas of Zhejiang province. The control group was chosen from people who lived in unpolluted area. Anticoagulation and coagulation peripheral venous blood samples were collected from 40 exposed persons (22 employees, 18 non-employees) and 36 exposed persons respectively. The oxidative, immune, Cd, Pb, Cr, Hg, and PCB indexes were detected. The contents of Cd, total PCB, MDA statistically increased in exposed group comparing with the control group (P < 0.05). The activity of SOD, GSH-Px, the percentage of helper/inducer T lymphocytes (CD4+) and the content of Cr in exposed group were less than those in the controlgroup (P < 0.05). Oxidative damage and immunotoxicity were observed in the group that lived in e-waste disposing areas. These effects were mainly related to the increase of Cd content or Cd and Pb contents in peripheral venous blood.
    Wei sheng yan jiu = Journal of hygiene research 03/2012; 41(2):199-203.
  • Article: [Pollution characteristics of PCBs in electronic waste dismantling areas of Zhejiang province].
    [show abstract] [hide abstract]
    ABSTRACT: To study the pollution level and distribution pattern of polychlorinated biphenyls (PCBs) in the environment media in electronic waste dismantling area of Zhejiang province. Water, soil and PM10 were sampled in electronic waste dismantling areas. The contents, distribution characteristics and toxic equivalents (TEQs) of PCBs in local environment were evaluated by ultra-trace detection methods. The PCBs contents of water, soil and PM10 in Luqiao and Zhenhai, the relatively high polluted areas, were higher than those in Longyou, the control area. The dominant PCBs detected from the environment in Luqiao were hexa-CBs (PCB138 and PCB153), while penta-CBs were dominant in Zhenhai and Longyou. TEQs in electronic waste recycling area were higher than those in control areas. The TEQs of PCBs in water and soil were the highest in Zhenhai, while the TEQs of PM10 were the highest in Luqiao. The local environment has been polluted by PCBs emitted from electronic waste recycling. PCBs pollution monitoring in electronic waste recycling area should be strengthened to prevent PCBs-induced health effects.
    Wei sheng yan jiu = Journal of hygiene research 09/2011; 40(5):583-6, 590.
  • Article: Correlations of PCBs, DIOXIN, and PBDE with TSH in children's blood in areas of computer E-waste recycling.
    [show abstract] [hide abstract]
    ABSTRACT: To study correlations of polychlorinated biphenyls (PCBs), DIOXIN, and polybrominated diphenyl ethers (PBDE) with thyroid stimulating hormone(TSH) in children, and assess the impact on children's health. Three hundred and sixty nine children aged from 6 to 8, including 195 from Luqiao, the computer E-waste recycling area, and 174 from Longyou, the control area, were selected for this investigation to elucidate the correlation of PCBs, DIOXIN, and PBDE with TSH in children's blood samples. The children had a physical examination and their blood levels of PCBs, DIOXIN, PBDE, and TSH were detected after sample collection. In the E-waste recycling area, the contents of PCBs, PBDE, DIOXIN, and TSH in the blood samples of children were 484.00 ± 84.86 ng·g(-1) lipid weight, 664.28 ± 262.38 ng·g(-1) lipid weight, 26.00 ± 19.58 ng·g(-1) lipid weight and 1.88 ± 0.42 μIU/mL (serum) respectively, while in the control area, the PCBs, PBDE, DIOXIN, and TSH contents were 255.38 ± 95 ng·g(-1) lipid weight, 375.81 ± 262.43 ng·g(-1) lipid weight, 39.64 ± 31.86 ng·g(-1) lipid weight, and 3.31±1.04 μIU/mL respectively. The health status of children in the control area are better than that in the contaminated area. Among children who are exposed to persistent organic pollutants, the pollutant content increases significantly in their serum, and the distribution of TSH levels in their bodies are also affected.
    Biomedical and Environmental Sciences 04/2011; 24(2):112-6. · 1.35 Impact Factor
  • Article: [Study of between persistent organic pollutants (POPs) content in children vein blood and thyroid stimulating hormone (TSH) in the capcitors dismantlement area].
    [show abstract] [hide abstract]
    ABSTRACT: To explore, in the capacitor dismantlement area, the exposure level of the PDP (PCB, Dioxin and PBDE) and the discrement situation of TSH in children vein blood. And analyze the correlation between the above 3 polluants and the TSH level in children. In 2 places, LuQiao and Long You, 108 and 123 children aged between 6 and 8 were selected to detect the health situation and measure the PCB, DIOXIN, PBDE, TSH levels in the vein blood, and use the SPSS software to get the correlation result between PCB, DIOXIN, PBDE and TSH and the difference of the above measurements in these 2 places. In LuQiao, the PCB, DIOXIN, PBDE, TSH measurements in the children vein blood were 484.00 +/- 84.66 ng g(-1) lipid weight, 26.00 +/- 19.58 ng/g lipid weight, ng/g lipid 664.28 +/- 262.38 weight, 1.88 +/- 0.42 mIU/L; In LongYou, the PCB, DIOXIN, PBD, TSH measurements in the children vein blood were 255.38 +/- 95.12 ng/g lipid weight, 39.64 +/- 31.86 ng/g lipid weight, 375.81 +/- 262.43 ng/g lipid weight, 3.31 +/- 1.04 mIU/L. In both places, the TSH measurements were in the range of normal reference; the correlation differences between PCB, DIOXIN, PBDE and TSH were relatively significant. In Lu Qiao area, the correlations between PCB, PBDE and TSH show relatively strong positive correlation, but DIOXIN and TSH shows slightly weak negative correlation. In Long You area, all of the 3 polluants show relatively strong positive correlations with TSH. There are significant difference TSH levels between except Lu Qiao and LongYou, other all no significant difference. PCB, DIOXIN and PBDE, these three kinds of matters have certain effect on the TSH discrement.
    Wei sheng yan jiu = Journal of hygiene research 09/2010; 39(5):580-2.
  • Article: Distribution of PCDD/Fs, PCBs, PBDEs and organochlorine residues in children's blood from Zhejiang, China.
    [show abstract] [hide abstract]
    ABSTRACT: Concentrations and congener specific profiles of PCDD/Fs, PCBs, PBDEs and organochlorine residues were measured in 22 pooled blood samples representing 66 children from both polluted areas (E-waste recycling region) and case control areas in Zhejiang province, China. To our knowledge, this is the first report on these pollutants in the blood of Chinese children. The mean concentrations of [summation operator]PCDD/Fs, [summation operator]PCBs, [summation operator]PBDEs, HCB and pp'-DDE in pooled blood samples from polluted areas (Luqiao) were 206+/-157 pg g(-1) lipid, 40.6+/-7.01 ng g(-1) lipid, 32.1+/-17.5 ng g(-1) lipid, 14.6+/-20.1 ng g(-1) lipid and 108+/-21.8 ng g(-1) lipid, respectively. WHO-TEQ-2005 for PCBs and PCDD/Fs were 11.9+/-4.62 pg g(-1) lipid and 10.3+/-6.39 pg g(-1) lipid, respectively. The results showed that PCBs, PBDEs and organochlorine residues in the E-waste recycling area were significantly (P<0.001) higher than the case control areas. High levels of PCDD/Fs were detected in the case control area (Longyou), where Na-PCP had been widely sprayed to prevent snailborne schistosomiasis. The contamination levels and profiles were compared with those documented in previous publications.
    Chemosphere 04/2010; 80(2):170-5. · 3.21 Impact Factor
  • Article: [Advance of study on the detoxification of the microcystin].
    Minglan Zheng, Xiaoming Lou
    [show abstract] [hide abstract]
    ABSTRACT: Contamination of water on toxic blooms of cyanobacteria has occurred in many regions of the world and could be a serious public health problem. It is hard to degrade all the microcystins by using ordinary waste water treatment process, so it is increasingly urgent to develop a new technology to deal with them. In this article the current ways of effectively removing microcystin toxins were reviewed.
    Wei sheng yan jiu = Journal of hygiene research 01/2007; 36(1):114-6.
  • Article: Distribution of PCDD/Fs, PCBs, PBDEs and organochlorine residues in children’s blood from Zhejiang, China
    [show abstract] [hide abstract]
    ABSTRACT: Concentrations and congener specific profiles of PCDD/Fs, PCBs, PBDEs and organochlorine residues were measured in 22 pooled blood samples representing 66 children from both polluted areas (E-waste recycling region) and case control areas in Zhejiang province, China. To our knowledge, this is the first report on these pollutants in the blood of Chinese children. The mean concentrations of ∑PCDD/Fs, ∑PCBs, ∑PBDEs, HCB and pp′-DDE in pooled blood samples from polluted areas (Luqiao) were 206 ± 157 pg g−1 lipid, 40.6 ± 7.01 ng g−1 lipid, 32.1 ± 17.5 ng g−1 lipid, 14.6 ± 20.1 ng g−1 lipid and 108 ± 21.8 ng g−1 lipid, respectively. WHO-TEQ-2005 for PCBs and PCDD/Fs were 11.9 ± 4.62 pg g−1 lipid and 10.3 ± 6.39 pg g−1 lipid, respectively. The results showed that PCBs, PBDEs and organochlorine residues in the E-waste recycling area were significantly (P < 0.001) higher than the case control areas. High levels of PCDD/Fs were detected in the case control area (Longyou), where Na-PCP had been widely sprayed to prevent snailborne schistosomiasis. The contamination levels and profiles were compared with those documented in previous publications.
    Chemosphere.