Weidong Zhanf

Publications (1)0 Total impact

• Article: [Ethyl acetate-soluble chemical constituents from whole plants of Senecio chrysanthemoides].

  Sheng Lin, Zhongxiao Zhanf, Yunheng Shen, Huiliang Li, Lei Shan, Runhui Liu, Xike Xu, Weidong Zhanf
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  ABSTRACT: To investigate the chemical constituents from the whole plants of Senecio chrysanthemoides. The chemical constituents were isolated and purified by chromatographic techniques over silica gel, Sephadex LH-20, preparative TLC and preparative HPLC. Structures of the compounds were identified by NMR and MS spectroscopic methods. Twenty five compounds were obtained and their structures were elucidated as seneciphyline (1), senecionine (2) , 1,2-dihydrocacalohastine (3) , eu-desm-4( 15)-ene-1beta,6alpha-diol (4), 7,11,15-trimethyl- 3methylidenehexadecane-1,2-diol (5), faradiol 3-O-palmitate (6),maniladiol 3-O-palmitate (7), faradiol (8), maniladiol (9), beta-amyrin (10), alpha-amyrin (11), betulin (12), loranthol (13), (+)-syringaresinol (14) , 1-hydroxy-4-oxo-cyclohexane-1-acetate (15), 2, 6-dimethoxy-p-benzoquinone (16), stigmasta-5, 22-dien-3beta-hydroxy-7-one (17) , stigmasta-5, 22-dien-7-one (18) , stigmasta-4-en-3-one (19), stigmasta-4,22-dien-3-one (20), beta-sitosterol (21), stigmasterol (22), daucosterol (23), glycerol 1-hendecanoate (24), and methyl hendecanoate (25). Compounds 5-9,13, 17-20 and 24 were obtained from the genus Senecio for the first time.
  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 05/2010; 35(9):1137-41.