Sabine Schröder

University of Cologne, Köln, North Rhine-Westphalia, Germany

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Publications (6)17.9 Total impact

  • Ophthalmology 06/2012; 119(6):1282-3.e4. DOI:10.1016/j.ophtha.2012.02.039 · 6.17 Impact Factor
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    Acta ophthalmologica 01/2012; 90(6):e500-1. DOI:10.1111/j.1755-3768.2011.02347.x · 2.51 Impact Factor
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    ABSTRACT: To investigate preoperative aqueous flare as a predictive factor for proliferative vitreoretinopathy (PVR) redetachment in patients with rhegmatogenous retinal detachment. Preoperatively, the aqueous flare of 116 consecutive patients with retinal detachment was measured quantitatively with a laser flare-cell meter (Kowa FM-500; Kowa Company, Ltd, Tokyo, Japan). Seventy-four healthy partner eyes and 41 eyes of healthy age-matched patients served as controls. At least 6 months after surgery, patients were reevaluated, whether surgery was performed again because of PVR redetachment. Eyes with retinal detachment that developed PVR redetachment later on (n = 12) had higher flare values than eyes with uncomplicated retinal detachment (n = 104) (median, 27.63 vs. 8.83 photon counts per millisecond; P < 0.0001). No eye with PVR redetachment had a flare value <10.8 photon counts per millisecond. In eyes with flare values exceeding 15 photon counts per millisecond, the odds of PVR redetachment development increases 16-fold. Our study shows that the breakdown of the blood-ocular barrier as determined by aqueous flare is a major risk factor for PVR redetachment. The laser flare-cell meter is a fast, noninvasive, and safe tool that allows predicting the PVR redetachment risk preoperatively. It provides the surgeon with an estimate to choose those patients who could benefit from intravitreal drugs to prevent PVR.
    Retina (Philadelphia, Pa.) 07/2011; 32(1):38-42. DOI:10.1097/IAE.0b013e3182173753 · 3.18 Impact Factor
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    ABSTRACT: Entwicklungsstörungen der Fovea sind fast immer mit einer Visusminderung assoziiert und treten im Rahmen verschiedender Syndrome auf. Wir berichten über eine Patientin mit unklarer Visusminderung, unauffälliger Anamnese und normalen funduskopischen, elektrophysiologischen und klinischen Befunden. Das Vorliegen einer Fovea plana konnte erst durch die Aufnahme mit der Spectral-Domain-OCT gesichert werden. Developmental disorders of the fovea are almost always accompanied by loss of visual acuity (VA) and are usually associated with different syndromes. We report on a young female patient with an unclear loss in VA, inconspicuous medical history and normal results for funduscopy, electrophysiology and clinical examinations. The presence of fovea plana could be confirmed by spectral-domain optical coherence tomography (OCT). SchlüsselwörterUnklare Visusminderung-Spectral-Domain-OCT-Fovea plana-Entwicklungsstörung-Multifokales Elektroretinogramm (ERG) KeywordsUnexplained loss of visual acuity-Spectral-domain OCT-Fovea plana-Developmental disorder-Multifocal electroretinography (ERG)
    Der Ophthalmologe 07/2010; 107(7):663-667. DOI:10.1007/s00347-010-2181-0 · 0.72 Impact Factor
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    Acta ophthalmologica 04/2010; 89(1):e98-9. DOI:10.1111/j.1755-3768.2010.01900.x · 2.51 Impact Factor
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    ABSTRACT: To investigate whether the emulsification of conventional silicone oils can be reduced by adding small amounts of silicone molecules of a very long chain length. Siluron 1000, Siluron 2000, Siluron 5000, Acri.Sil-Ol 5000, Oxane 5700, Densiron 68 LV, Densiron 68 and Densiron 68 HV (0.5 ml) were each tested along with either plasma or serum (0.5 ml) in a glass cuvette. Emulsification was induced by sonication and documented by photography. The total area of emulsified oil was assessed using the ImageJ software. The addition of small amounts of very-long-chain silicone molecules significantly reduced the emulsification for 1000 cSt silicone oil (Siluron 2000) and for 1000 cSt silicone oil with an admixture of F6H8 (Densiron 68 HV). New low-viscosity silicone oils show a reduced emulsification similar to that of 5000 cSt oils. In future, it may be possible to avoid using 5000 cSt oils. The findings may foster silicone oil surgery in general, and in particular the application of small-incision techniques.
    The British journal of ophthalmology 12/2009; 94(4):509-12. DOI:10.1136/bjo.2009.170852 · 2.81 Impact Factor