[show abstract][hide abstract] ABSTRACT: Three cases of transfusion-transmitted malaria in Canada are described. Although very rare, this diagnosis should be considered in transfusion recipients who have undiagnosed symptoms consistent with malaria. Thick and thin blood smears should be urgently examined to exclude this possibility.
Canadian Medical Association Journal 03/2001; 164(3):377-9. · 6.47 Impact Factor
[show abstract][hide abstract] ABSTRACT: To review community-acquired needle stick injuries (CANSIs) in children reported to a Canadian emergency room-based injury surveillance program.
Analysis of 1991 to 1996 CANSI records followed by chart review to determine use of prophylactic interventions and outcome information.
The Canadian Hospitals Injury Reporting and Prevention Program network of 10 paediatric and six general hospitals.
Nonoccupational injuries to patients younger than age 20 years involving used needles were reviewed.
Of 116 children injured, most were male (74%); the median age was 6.6 years. Needles were picked up before injury in 77% of the cases. Most injuries (78%) were from needles presumed to have been discarded by an injection drug user. Parks were the most common site of injury (21%). Six per cent of injuries occurred in medical settings. Treatment information was obtained for 71 (61%) patients. Only 1.7% had been immunized against hepatitis B virus before injury. Hepatitis B immune globulin and hepatitis B virus vaccine were given to 78% and 76% of children, respectively. None received human immunodeficiency virus prophylaxis.
Programs teaching needle avoidance may help prevent many CANSIs. The safety of outdoor, home and medical environments also needs to be ensured. Treatment guidelines for CANSIs will help ensure appropriate postinjury management.
Paediatrics & child health 09/2000; 5(6):324-8. · 1.03 Impact Factor
[show abstract][hide abstract] ABSTRACT: GB virus C (GBV-C)/hepatitis G virus (HGV) is a recently recognized parenterally and sexually transmitted agent. The prevalence of GBV-C/HGV markers in Canadian blood donors has not been previously studied and was therefore determined.
Blood donors [identity unlinked (IU), short-term temporarily deferred (STTD) and autologous groups] and donor samples with antibodies to hepatitis C (anti-HCV) or hepatitis B core were tested for GBV-C/HGV RNA and for antibodies to E2 antigen (anti-E2).
GBV-C/HGV RNA was found in 1.1% and anti-E2 in 7.3% of the combined IU/STTD donor group. Viremia was much more common in anti-HCV-positive samples (12.5%); anti-E2 was present in >50% of this group. In the STTD group, female gender was significantly associated with viremia.
GBV-C/HGV infection is relatively common in Canadian donors, and a small proportion are viremic. The association of female gender and viremia was unexpected. Further study is needed to clarify the epidemiology and natural history of GBV-C/HGV infection.
[show abstract][hide abstract] ABSTRACT: THREE CASES OF TRANSFUSION-TRANSMITTED MALARIA in Canada are described. Although very rare, this diagnosis should be considered in transfusion recipients who have undiagnosed symptoms consistent with malaria. Thick and thin blood smears should be urgently examined to exclude this possibility.
Canada communicable disease report = Relevé des maladies transmissibles au Canada 04/1999; 25(6):53-62.