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ABSTRACT: Pain and swelling of the medial end of the clavicle may be associated with radiographic sclerosis. The commonest causes are osteoarthritis, infection and condensing osteitis of the clavicle. Distinguishing between these clinically and radiologically can be difficult but computed tomography (CT) and magnetic resonance imaging (MRI) are often useful for their differentiation. In this review, the typical imaging features of these conditions are presented with an emphasis on the CT and MRI appearances. These are correlated with clinical features, which together should enable a confident diagnosis to be made.
Clinical Radiology 12/2004; 59(11):992-9. · 1.95 Impact Factor
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Clinical Radiology 07/2002; 57(6):532-4. · 1.95 Impact Factor
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ABSTRACT: We describe the use of a fat-based low density oral contrast agent in computed tomography (CT) of the upper abdomen. It has a CT number of -71 Hounsfield units (HU) and allows excellent visualization of the bowel wall and adjacent structures as well as reducing the artefacts seen with iodinated high density contrast.
British Journal of Radiology 02/1995; 68(805):80-1. · 1.31 Impact Factor
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ABSTRACT: Mediastinal lymphadenopathy is commonly detected on CT. It is a non-specific finding, but because of its significance in the treatment in lung carcinoma it is important to know with which other disease states it is associated. We present a series of 42 patients in whom CT of the chest was used to confirm a clinical diagnosis of bronchiectasis. The size, number and distribution of mediastinal lymph nodes is documented. Lymph nodes were visible in 81% of patients. Nodes larger than 10 mm, the recognised maximum size for normal nodes in the U. K., were detected in 29%. In the absence of other recognised causes of lymphadenopathy in these patients, these findings confirm "reactive" mediastinal lymph node enlargement in bronchiectasis.
Acta Radiologica 10/1993; 34(5):489-91. · 1.37 Impact Factor
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Clinical Radiology 12/1991; 44(5):327-8. · 1.95 Impact Factor
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ABSTRACT: Tumour burden is a significant prognostic factor in patients with colorectal liver metastases, and can be staged according to percentage hepatic replacement (PHR), but accurate measurements of PHR are difficult to obtain. We have used an automated computerized technique to isolate tumour and measure PHR from computed tomography images of 22 patients. Tumour identification was achieved by establishing local histogram-based thresholds at liver-tumour boundaries displaying clear bimodal histogram distributions. There was a significant association between measured PHR and independent visual estimates of PHR stage defined in quartiles (p less than 0.001). When the measured value of PHR differed from the PHR stage, the visual estimate was always higher. The accuracy of PHR measurement was assessed on stimulated liver computed tomography images. It seems likely that visual estimates of PHR from computed tomography images tend to overestimate tumour extent. The automated technique is probably more accurate and will be useful for assessing and monitoring patients.
British Journal of Radiology 07/1991; 64(762):494-7. · 1.31 Impact Factor
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ABSTRACT: Thirteen patients with metastatic non-seminomatous germ cell tumours and enlarging metastases consisting of teratoma differentiated only were identified. Patients were managed with surgical resection soon after the growing lesions were documented. Surgical morbidity was minimal and 12 patients are alive (10 are disease-free) at a median follow-up of 28 months.
British Journal of Urology 03/1991; 67(2):195-202.
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ABSTRACT: Rounded atelectasis (folded lung syndrome) is a form of pulmonary collapse associated with pleural thickening that can mimic a neoplasm on plain chest radiographs. The abnormality was diagnosed radiologically in nine patients in whom follow-up varied from 1 to 6 years. Four patients had bilateral lesions, making a total of 13 examples. The CT findings were analyzed and compared with previously published criteria for the diagnosis of this disorder. In all cases, CT showed a rounded mass, 3.5-7.0 cm in diameter, abutting a thickened pleural surface in the lung periphery. The margin closest to the hilum was blurred by the entering vessels in 92% of the cases. Our experience suggests that the CT findings of rounded atelectasis are characteristic of the abnormality.
American Journal of Roentgenology 09/1989; 153(2):257-60. · 2.78 Impact Factor
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ABSTRACT: The percentage hepatic replacement (PHR) with liver metastases has been recognised as an important factor for patient management, prognosis, and clinical trial evaluation. The PHR can be assessed by various methods including ultrasound, radioisotope, or computed tomography (CT) imaging, or by inspection and palpation at laparotomy. We report a prospective study comparing these methods of PHR assessment in 56 consecutive patients with colorectal liver metastases. When all four methods were used complete agreement was achieved in only 35% of cases (9/26). The three imaging techniques agreed in only 37% of cases (14/38). Overall, the correlation between different methods was poor with a tendency for surgery to underestimate the PHR. However, CT and surgery agreed in 81% of cases (21/26), and CT gave a higher estimate than surgery in each of the other five patients. With such variability in the estimates of PHR derived from these different techniques, consideration must be given to which technique is used. It is concluded that CT is probably the most accurate for PHR assessment at present.
Annals of The Royal College of Surgeons of England 02/1989; 71(1):11-3. · 1.23 Impact Factor
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ABSTRACT: We report measurements of absorbed dose to vertebral metastases in ten patients referred for 89Sr therapy for disseminated prostatic carcinoma. Patients received a tracer dose of 85Sr at the time of 89Sr treatment and metastatic strontium retention was monitored scintigraphically for 6 mo. Metastatic 85Sr activity corrected for tissue attenuation was measured using the conjugate view principle, with special care taken to eliminate errors due to the selection of the metastatic region of interest. Metastatic volume was determined from high resolution CT images, and density inferred from Hounsfield number using the QCT bone mineral calibration of Genant and Cann. The mean absorbed dose was 850 rad/mCi (23 cGy/MBq) with a range from 220-2260 rad/mCi (6 to 61 cGy/MBq). The wide range found was consistent with the variation expected to arise due to differences in strontium renal plasma clearance (range 0.1-11.81/day) and extent of skeletal metastatic disease (varying from two small metastases to a superscan on [99mTc]MDP images) among the patients studied.
Journal of Nuclear Medicine 05/1988; 29(4):549-57. · 6.38 Impact Factor
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ABSTRACT: Intersex states are rare but if unsuspected may cause diagnostic confusion. We describe one such patient with true hermaphroditism which was misdiagnosed on computed tomography (CT). Laparotomy revealed a female genital tract and histology confirmed the presence of ovatestes, despite a male phenotype.
Clinical Radiology 12/1986; 37(6):593-4. · 1.95 Impact Factor
