[Show abstract][Hide abstract] ABSTRACT: Background and objectives:
The red blood cell distribution width (RDW) has been found to be associated with cardiovascular morbidity and mortality. The objective of this study was to determine whether the RDW measures are associated with the coronary artery calcification score (CACS) in patients who did not present with obvious coronary heart disease (CHD).
Subjects and methods:
A total of 527 consecutive patients with a low to intermediate risk for CHD but without obvious disease were enrolled in this study. The study subjects underwent coronary computerized tomography angiography and CACS was calculated. The patients were divided into two groups based on CACS: Group I (CACS≤100) and Group II (CACS>100). The two groups were compared in terms of classic CHD risk factors and haematological parameters, particularly the RDW.
Group I patients were younger than Group II patients. The Framingham risk score (FRS) in patients of Group II was significantly higher than that in patients of Group I. Group II patients had significantly elevated levels of haemoglobin, RDW, neutrophil count, and neutrophil/lymphocyte ratio compared with Group I patients. CACS was correlated with age, RDW, and ejection fraction. In the multivariate analysis, age, RDW, and FRS were independent predictors of CACS. Using the receiver-operating characteristic curve analysis, a RDW value of 13.05% was identified as the best cut-off for predicting the severity of CACS (>100) (area under the curve=0.706).
We found that the RDW is an independent predictor of the CACS, suggesting that it might be a useful marker for predicting CAD.
Korean Circulation Journal 09/2015; 45(5):372. DOI:10.4070/kcj.2015.45.5.372 · 0.75 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: OBJECTIVE:
The aim of the present study was to investigate the relationship between pericoronary fat and the severity and extent of atherosclerosis, quantified using 64-multidetector computed tomography, in patients with suspected coronary artery disease.
The study population consisted of 131 patients who were clinically referred for noninvasive multislice computed tomography coronary angiography for the evaluation of coronary artery disease. Patients were classified as follows: no atherosclerosis, Group 1; nonobstructive atherosclerosis (luminal narrowing <50% in diameter), Group 2; and obstructive atherosclerosis (luminal narrowing ≥50%) in a single vessel or obstructive atherosclerosis in the left main coronary artery and/or multiple vessels, Group 3. Epicardial adipose tissue was defined as the adipose tissue between the surface of the heart and the visceral layer of the pericardium (visceral epicardium). Epicardial adipose tissue thickness (mm) was determined in the right ventricular anterior free wall. The mean thickness of the pericoronary fat surrounding the three coronary arteries was used for the analyses.
The average thickness over all three regions was 13.2 ± 2.1 mm. The pericoronary fat thickness was significantly increased in Group 3 compared with Groups 2 and 1. The epicardial adipose tissue thickness was significantly increased in Group 3 compared with Groups 2 and 1. A receiver operating characteristic curve for obstructive coronary artery disease was assessed to verify the optimum cut-off point for pericoronary fat thickness, which was 13.8 mm. A receiver operating characteristic curve for obstructive coronary artery disease was also assessed to verify the optimum cut-off point for epicardial adipose tissue, which was 6.8 cm.
We showed that the epicardial adipose tissue and pericoronary fat thickness scores were higher in patients with obstructive coronary artery diseases.
[Show abstract][Hide abstract] ABSTRACT: Carpal tunnel syndrome is the most common upper extremity neuropathy in the wrist that may be associated with anatomic variations of median nerve. Trifurcation of the median nerve has been very rarely reported in the literature. We report coexistence of bilateral median nerve variation in the wrist and its radiological features. Ultrasonography and magnetic resonance imaging was performed to the patient after Tinel and Phalen tests. There was bifurcation and trifurcation of the median nerve in right and left wrists respectively. Bilateral carpal tunnel syndrome was caused by bilateral median nerve variation in the present case. When a median nerve variation is detected in one wrist, a possible variation at the other side should be kept in mind and hence should be evaluated. A thorough knowledge of the variations of the median nerve is essential in order to avoid surgical complications and to ensure optimal patient outcome. US is an easy and cheap radiological method for diagnosis and it should be the first chosen radiological technique to evaluate median nerve variations in idiopathic CTS patients.
[Show abstract][Hide abstract] ABSTRACT: Persistent left superior vena cava is a rare but important congenital vascular anomaly. However, PLSVC with absent RSVC (isolated PLSVC) is a very rare venous malformation We report on a rare case of persistent left superior vena cava (PLSVC) with absent right superior vena cava (RSVC).
This venous malformation was identified incidentally in a 69-year-old woman during chest multi-detector computed tomography (MDCT). On chest MDCT, the SVC was noted on the left side. A bridging vein drained the right jugular and right subclavian veins and joined the left brachiocephalic vein in order to form the PLSVC, which descended on the left side of the mediastinum and drained into the left atrium (LA). The patient had no additional cardiac anomaly.
Isolated PLSVC is usually asymptomatic but it can pose difficulties for establishing central venous access, pacemaker implantation and cardiothoracic surgery. This condition is also associated with an increased incidence of congenital heart disease, arrhythmias and conduction disturbances. A wide spectrum of clinicians should be aware of this anomaly, its variations and possible complications.
Polish Journal of Radiology 10/2012; 77(4):65-6. DOI:10.12659/PJR.883632
[Show abstract][Hide abstract] ABSTRACT: BACKGROUND: The exact mechanisms behind the association between atherosclerosis and gamma-glutamyltransferase (GGT) are unclear. Coronary artery calcification (CAC) detected by computerized tomography is an important marker of atherosclerosis and its severity correlates with coronary plaque burden. The aim of this study was to investigate if serum GGT levels are associated with CAC in patients without known coronary heart disease (CHD) who had low-intermediate risk for CHD. METHODS: Two hundred and seventy two patients who had low-intermediate risk for coronary artery disease were included in the study. Serum GGT levels were measured spectrophotometrically. CACS (Agatston method) were performed using a 64-slice computerized tomography scanner. The patients were grouped according to their GGT values in four quartiles. RESULTS: Patients in higher GGT quartiles had elevated CAC score (P<0.001). Patients in higher GGT quartiles were predominantly males (P<0.001) and were more likely to be smoking (P=0.004), and have elevated uric acid (P<0.001), fasting blood glucose (P<0.001), CRP levels (P=0.003) and 10-year total cardiovascular risk (P=0.007) and low HDL levels (P<0.001). Positive correlations were found between log GGT and CAC (r=0.233, P<0.001). In the multivariate analysis GGT, age, smoking and serum uric acid levels appeared as independent factors predictive of presence of CAC. CONCLUSIONS: We demonstrated a significant correlation between serum GGT levels and CAC and CHD risk factors. Serum GGT level was an independent marker of CAC.
International journal of cardiology 04/2012; 167(4). DOI:10.1016/j.ijcard.2012.03.157 · 4.04 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Atretic parietal cephaloceles are an extremely rare and occult form of congenital herniations that involve the meninges, remnants of glial cells or central nervous system structures. They are detected as subscalp lesions that are covered by skin. In the literature, atretic parietal cephaloceles have been reported in children in 59 cases and in two cases in adults. We present here a case of a recurrent atretic parietal cephalocele that we recently observed in an adult. This case indicates that an atretic parietal cephalocele should always be considered in the differential diagnosis of subscalp lesions. Radiologic diagnosis is a lifesaving measure that can be undertaken before an operation. Additionally, regular follow-up magnetic resonance imaging is recommended for each case with remnant lesions due to the slow growth of these masses.
Eurasian Journal of Medicine 04/2012; 44(1):58-59. DOI:10.5152/eajm.2012.13
[Show abstract][Hide abstract] ABSTRACT: Multislice computed tomography (MSCT) is an easy, fast and reliable imaging technique for evaluation of the cardiovascular system. 64-slice multidetector CT gives an accurate and noninvasive depiction of coronary arteries and presence of anomalous coronary arteries. Coronary artery fistula is a rare congenital anomaly. It is a connection between one or more of the coronary arteries and a cardiac chamber or great vessel.They are usually discovered as an incidental finding at coronary angiography. In this case report we present a 49-year-old man who complained of shortness of breath and chest pain on exertion with left anterior descending artery (LAD)- main pulmonary artery (MPA) fistula. MSCT showed stenosis of left anterior descending coronary artery. There was fistulization of LAD to MPA as well.
Gazi Medical Journal 03/2011; 22(1):21-23. DOI:10.5152/gmj.2011.05
[Show abstract][Hide abstract] ABSTRACT: Polycystic ovary syndrome (PCOS) is independently associated with the major cardiovascular risk factors. The aim of this study was to examine the echocardiographic profiles of patients with PCOS using conventional echocardiographic methods and tissue Doppler imaging.
For this study, we have registered 48 women with PCOS and 21 healthy control subjects who were matched with respect to age and body mass index. Standard two-dimensional and M-mode measurement, transmitral valve flows and tissue Doppler imaging of mitral and tricuspid anulus were recorded.
In PCOS and control groups, left ventricular and atrium diameters, ejection fraction, mitral E/A ratio, deceleration time and isovolumic relaxation time were similar. There were no significant differences between patients with PCOS and control subjects with respect to tissue Doppler profiles.
Patients with PCOS execute echocardiographic measures of cardiac function that are similar to those of healthy women.
[Show abstract][Hide abstract] ABSTRACT: Multislice computed tomography (MSCT) is a promising noninvasive method of detecting coronary artery disease. However, most data have been obtained in selected series of patients. The purpose of this study was to investigate the accuracy of 64-slice CT in consecutive patients with suspected or proven coronary artery disease.
Seventy-three consecutive patients (57 males, 16 females; mean age 59+/-9 years; range 33 to 83 years) were examined by 64-slice CT before coronary angiography (CA). Eight patients had a history of percutaneous coronary intervention and stenting and five patients had a history of coronary artery bypass grafting. Sensitivity, specificity, and positive (PPV) and negative (NPV) predictive values of MSCT for the detection of significant stenosis were calculated on a segmental, vessel, and patient basis.
Sixty-one patients were diagnosed as having at least one significant stenosis with CA. Of these, MSCT identified 58 patients correctly. Two patients were incorrectly diagnosed as having one-vessel disease by MSCT. Patient-based sensitivity, specificity, NPV, and PPV of MSCT were 95.1%, 83.3%, 76.9%, and 96.7%, respectively. Of 1065 segments evaluated, CA detected 141 significant stenoses. On MSCT, significant stenoses were correctly diagnosed in 116 segments. Twenty-four nonsignificant lesions were overestimated by MSCT. In segment-based analysis, the overall sensitivity was 82.3%, specificity was 97.4%, NPV was 97.3%, and PPV was 82.9%. The accuracy of MSCT was in full agreement with CA in the evaluation of stent and graft patency.
Our findings show that 64-slice CT is highly accurate for the detection of significant coronary artery disease in an unselected patient population and can be used as a noninvasive technique.
Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 03/2010; 38(2):95-100.
[Show abstract][Hide abstract] ABSTRACT: Osteochondromas are the most frequently occurring bone tumors. However, they rarely arise in subungual locations. Clinically they appear as slow-growing masses causing deformity of the overlying nail. Here we evaluate a case of subungual osteochondroma of the little finger that is very rare in the literature. Radiological findings were diagnostic, and local tumor excision was the treatment of choice. The diagnosis was performed by a plain radiographic film and the lesion was completely detached from the nail bed. If a dense lesion detected in little finger of a young patient, it should be bear in mind that the lesion may be osteochondroma and complete removal may be chosen instead of biopsy.