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ABSTRACT: Bei 8 Patienten mit implantiertem Schrittmacher (3 unipolare, 5 bipolare Systeme) wurde das Risiko einer Beeinflussung der
regulären Schrittmacherfunktion durch Thermotherapie bei einer Frequenz von 434 MHz und einer maximalen Leistung von 110 Watt
untersucht. Das Ergebnis unserer Studie zeigt, daß bei Patienten mit implantiertem Schrittmacher die Thermotherapie zur Behandlung
der benignen Prostatahypertrophie ohne Risiko einer Schrittmacherfunktionsstörung angewendet werden kann.
In 8 patients with implanted pacemaker (3 unipolar, 5 bipolar systems) the risk of interference of a regular pacemaker function
and an energy source with a capacity of 110 Watt and a frequency of 434 MHz was investigated. The results show that thermotherapy
in patients with prostatic hypertrophy can be used without the risk of interference with regular pacemaker function.
Herzschrittmachertherapie & Elektrophysiologie 04/1997; 8(1):68-71.
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ABSTRACT: In 8 patients with implanted pacemaker (3 unipolar, 5 bipolar systems) the risk of interference of a regular pacemaker function and an energy source with a capacity of 110 Watt and a frequency of 434 MHz was investigated. The results show that thermotherapy in patients with prostatic hypertrophy can be used without the risk of interference with regular pacemaker function.
Herzschrittmachertherapie & Elektrophysiologie 04/1997; 8(1):68-71.
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ABSTRACT: This study for the first time elaborates on cells of the immune system present in benign prostatic hyperplasia (BPH). Compared with normal prostate, all BPH-derived specimens revealed a marked increase of CD45+ leukocytes, characterization of which demonstrated three major cell types, i.e., CD3+ T lymphocytes, CD11c+ macrophages and CD20+ B lymphocytes. Frequencies of CD3+ cells/mm2 of cryocut sections were increased at least 10 times in BPH specimens, and the CD8+:CD4+ T suppressor/cytotoxic:T helper cell ratio was reversed. The infiltrating leukocytes predominantly populate the interstitium and accumulate around epithelial ducts which, however, were found to be invaded and/or destroyed only in a number of cases. Phenotypic alterations of surface antigen expression on prostate epithelial cells in BPH that might be due to the presence of lymphocytes were examined by using monoclonal antibodies (mAb) directed against human leukocyte antigens (HLA). Whereas anti-HLA-DR reactivity in normal prostate is restricted to small numbers of macrophages and includes neither prostate epithelial cells nor prostate T cells, it was found to be dramatically increased in BPH, comprising CD45+ cells and prostate epithelial cells as demonstrated by double-staining with anti-cytokeratin or anti-prostate-specific antigen. A mean of 40% of analyzed epithelial glands in BPH reacted with anti-HLA-DR, but not with anti-DQ or -DP monoclonal antibodies. A new method for the enrichment of prostate-derived lymphocytes was established to facilitate phenotypic analysis by flow cytometry, demonstrating 70 to 80% of enriched CD45+ cells to stain for CD3, approximately 60% thereof for CD4, 30% for CD8, and the remaining 10% with anti-CD20, a pan-B-cell marker. Flow cytometry showed that, in contrast to peripheral T cells, both CD4+ and CD8+ prostatic T cells were positive for the T cell activation markers HLA-DR and interleukin-2-receptor.
Laboratory Investigation 02/1992; 66(1):96-107. · 3.64 Impact Factor
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ABSTRACT: The survival rate among patients with colorectal cancer classified as Dukes' B or C who underwent extended resection due to infiltration of neighboring structures is significantly lower than among patients in the same Dukes' stage without infiltration of adjacent structures. Seventy-one patients with rectosigmoid cancer (37 primary and 34 recurrent tumors) involving the urogenital tract were retrospectively analyzed. Patients with primary tumors had a markedly higher mean survival rate after radical surgery (60.7 months) than after palliative procedures (28.2 months), while no such difference was seen among patients with recurrent tumors (17.6 or 14.1 months, respectively). From the urologic point of view, radical intervention is mandatory in cases of primary rectosigmoid carcinoma involving the urogenital tract. Aggressive surgery for recurrent tumors appears questionable, however; in these cases, priority should be given to improving the quality of life, recommending palliative surgery as the preferable approach.
European Urology 02/1992; 22(3):213-7. · 8.49 Impact Factor
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ABSTRACT: The urinary stone, serum and 24-hour urine concentrations of 14 trace elements were determined in urinary stone patients by inductively coupled plasma atomic-emission spectroscopy. The data obtained for 25 active stone patients and 32 whose last stone episode had occurred at least 12 months previously were compared with those of 25 healthy individuals. Urinary nickel, manganese and lithium excretion, and serum nickel, manganese and cadmium concentrations were statistically significantly lower for active stone patients compared to those with previous stone episodes and healthy individuals. No difference in the concentrations of trace elements could be found, however, for patients with previous stone episodes and healthy individuals. Nickel, manganese, lithium and cadmium could be of significance in the pathological mechanism of stone formation, not from mineralogical or crystallographic viewpoints but for the smooth flow of enzymatic reactions in biological systems.
The Journal of Urology 02/1991; 145(1):93-6. · 3.75 Impact Factor
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ABSTRACT: In 111 patient suffering from calcium oxalate lithiasis more than 168 citrate and calcium analyses have been performed in 24 hour urine. In 69 patients with a single stone episode no significant difference of citrate concentration was found in comparison with 63 healthy volunteers. However, in 42 recurrent stone formers was the citrate concentration significantly diminished (p less than 0.005). The calcium/citrate ratio was in recurrent stone formers markedly higher (5.19 +/- 8.6) than in patients with a single stone episode (3.34 +/- 4.9). However, because great deviation of citrate values the calcium/citrate ratio may not be suitable for evaluation of stone formation risk.
Zeitschrift für Urologie und Nephrologie 12/1990; 83(11):597-602.
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ABSTRACT: 30 patients who developed an irradiation bladder after radiotherapy of carcinoma uteri were treated with submucosal infiltration of orgotein. In this homogeneous series (same cancer, dosage and exposition of radiation, same sex) the success rate of 86% improvement of subjective symptoms or complete healing was excellent, not to be reached by any other mode of treatment. In one patient an anaphylactic shock was seen. Despite of this event--which happens in great published series in only 1 permille--orgotein infiltration should be the therapy of choice in actinic damaged urinary bladders.
Zeitschrift für Urologie und Nephrologie 06/1988; 81(5):305-8.
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ABSTRACT: The beneficial effect of allopurinol treatment in metaphylaxis of hyperuricosuric calcium oxalate lithiasis has been analyzed in a retrospective study covering 10 years. 83 patients with hyperuricosuric calcium oxalate lithiasis (48 recurrent stone formers, 35 patients with a single stone episode) were treated with 300 mg allopurinol for 33.1 +/- 11.5 months. Subsequently, each patient was controlled for 43.9 +/- 27 months without therapy. The overall relapse rate was 28.9% but there is no statistically significant difference between treatment with and without allopurinol (Mann-Whitney: p = 0.16). The only striking difference was the fact that, with one exception, stone relapses occurred only in the group of recurrent stone formers, whereas the group with single stone formation seemed to be at a clearly decreased risk for stone recurrence during follow-up. This would suggest that factors other than those investigated in this study are responsible for the phenomenon of recurrent stone formation.
European Urology 02/1988; 15(3-4):227-9. · 8.49 Impact Factor
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ABSTRACT: iCT was determined in 74 patients by direct RIA. A highly significant increase (371 pg/ml) compared with normal serum concentration (100 pg/ml) was observed. There was no correlation between iCT concentration and ejaculate parameters. In addition monomeric bioactive CT and from the same RNA derived KT were determined from a seminal plasma pool gathered from 25 patients. The measured amounts were similar to those found in plasma. Monomeric CT or KT is not responsible for high amounts of iCT in seminal plasma found by direct radioimmunoassay. High amounts of iCT or iKT are due to two heterogenous peptides with greater molecular mass but have no influence on fertility.
Experimental and clinical endocrinology 12/1986; 88(1):89-94.
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ABSTRACT: In 12 patients with bladder tumors and in 15 undergoing multiple biopsies of grossly normal bladder mucosa to monitor the course of their bladder cancer, attempted staining of the mucosa with methylene blue failed to show any correlation with tumor histology. While histologically normal mucosal areas picked up the stain well, nonstaining areas were found to be dysplastic in 22% of the cases and showed endophytic masses in 2 patients. In 48% of patients excessive staining prevented adequate evaluation so that repeated endoscopy was necessary to confirm the absence of tumorous tissue. For these reasons, staining of the bladder mucosa with methylene blue is unsuited for the diagnosis of endophytic bladder tumors.
European Urology 02/1985; 11(4):217-9. · 8.49 Impact Factor
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ABSTRACT: The present paper demonstrates the various methods in surgical treatment of complicated nephrolithiasis. The techniques of extended intrasinusal pyelocalicotomy, multiple radial nephrotomies, classic anatrophic nephrotomy, doppler-guided nephrotomies and highly selective anatrophic nephrotomy are described. The advantages and disadvantages of these methods are summarized and the results of treatment in 58 patients are presented.
Der Urologe 02/1984; 23(1):13-9. · 0.50 Impact Factor
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ABSTRACT: The infiltration of the ureters, bladder or urethra by recurrent colorectal carcinoma raises both urodynamic and surgical problems. These include the question of whether reconstruction or urinary diversion is indicated. The present paper describes the surgical procedures carried out in 19 patients with tumour extention of recurrent colorectal carcinoma to the urinary tract. In the majority of cases the treatment of choice can be decided only intraoperatively. It is important to choose the procedure which guarantees both surgical radicality and minimal discomfort to the patient.
Wiener klinische Wochenschrift 05/1983; 95(9):286-91. · 0.81 Impact Factor
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ABSTRACT: In the rabbit model renal cortical blood flow after 60 min of normothermic ischemia is seen to rise significantly in the early reperfusion period. Under otherwise identical conditions this phenomenon is absent after hypothermic ischemia produced by surface cooling of the kidney and in sham-operated kidneys. It is still unclear whether postischemic hyperemia is a physiologic counterregulatory mechanism in response to 60-min normothermic ischemia of the rabbit kidney or a contributory factor in the development of acute postischemic renal failure.
Urologia Internationalis 02/1983; 38(4):209-12. · 0.99 Impact Factor
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ABSTRACT: Of 264 patients with urolithiasis those with pure uric acid or urate stones were compared to those with other types of calculi for differences in epidemiologic factors and uric acid, calcium and phosphate metabolism. Patients with uric acid stones were predominantly older men. These patients had comparatively lower incomes and spent less money on food but consumed more alcohol. The urinary pH was lower than in the other groups. The absence of abnormally elevated serum uric acid levels and elevated 24-hour urinary uric acid excretion suggests this variety of uric acid lithiasis to be idiopathic in nature. This finding is supported by the results of standardized oral purine loading, which showed no post-loading differences in serum levels and revealed urinary concentrations in 12 patients with pure uric acid stones and 10 normal subjects. However, there is evidence to suggest that this condition may be a precursor of primary gout. Hereditary mechanisms are absent and the relapse rate is the same as in patients with other stones. Therefore, our results suggest the existence of an idiopathic variety of uric acid lithiasis that, at least in central Europe, occurs more frequently than previously assumed. The condition is not inherited, alcohol consumption is a major etiologic factor and there is no evidence of a causative role of abnormalities in purine metabolism.
The Journal of Urology 01/1983; 128(6):1219-23. · 3.75 Impact Factor
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O Zechner
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ABSTRACT: The present study describes the mode of prophylactic management of urinary stone disease as carried out at the Department of Urology. University of Vienna Medical School. A carefully directed prophylactic regimen results in a significant decrease in the recurrence rate of stone formation.
Wiener klinische Wochenschrift 11/1981; 93(20):619-24. · 0.81 Impact Factor
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ABSTRACT: The social infrastructure was investigated in 379 patients with urinary stones. The rates of 50% for employees and 32% for old-age pensioners were surprisingly high. 16% of the patients were employed in jobs with hard manual labour. Only 9% of the patients went in for regular physical activity in their leisure. A significant increase in urinary excretion of calcium and uric acid (p - 0.01) and inorganic phosphate (p less than 0.001) was seen in connexion with increase in net income. On the other hand, urinary pH was lowest in the highest income group (p = 0.01). According to these findings an increased net income combined with a lack of physical exercise seems to enhance the risk of stone formation.
Wiener klinische Wochenschrift 11/1981; 93(20):635-8. · 0.81 Impact Factor
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ABSTRACT: Oral purine loading: a diagnostic procedure in stone forming patients. 95 stone formers (83 patients with calcium oxalate and calcium phosphate, 12 patients with uric acid stones) and 10 healthy volunteers were given 2 g guanosine as an oral purine load. Calcium oxalate and caldium phosphate stone formers showed two different patterns of uric acid excretion after oral purine loading, correlating with different incidence of recurrent stone formation. Patients with uric acid lithiasis showed initially lower values of urate excretion, after oral purine load no difference of uric acid excretion compared to normal controls was seen.
Helvetica chirurgica acta 09/1981; 48(3-4):485-8.
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ABSTRACT: The relationships between eating and drinking habits, and serum as well as 24-hour urinary concentrations of calcium, inorganic phosphate uric acid and urinary pH were studied in 379 patient in whom stones form. The 24-hour urinary calcium excretion was found to be increased in patients who preferably eat animal proteins and farinaceous foods (p less than 0.1). Regarding drinking habits, urinary calcium and inorganic phosphate excretion was found to increase significantly as a function of alcohol ingestion (p less than 0.01 and p less than 0.001, respectively). Similarly, an increased alcohol intake was found to be associated with higher serum uric acid concentrations (p less than 0.01). A significant increase in urinary pH was confined to patients preferably eating vegetables (p less than 0.005). The results of our study suggest alcohol consumption to be a potentiating factor for the risk of stone formation.
The Journal of Urology 02/1981; 125(1):51-4. · 3.75 Impact Factor
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ABSTRACT: We present a model for oral uric acid loading which may be used to study the relapsing tendency of stone-formers. The oral administration of 2 g of guanosine was associated with two different response patterns of urinary uric acid excretion in patients with urolithiasis. The two groups also had considerably different relapse rates. The relapsing tendency in the group with the comparatively decreased reaction of urate excretion was less pronounced than in the group with enhanced uric acid excretion after oral purine loading.
Investigative urology 10/1980; 18(2):115-8.
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ABSTRACT: The causes of, and physiopathological factors underlying the most common metabolic disorders implicated in the formation of renal stones are reviewed. These include hypercalciuria, hyperoxaluria, renal tubular acidosis, cystinuria and disturbances of purine metabolism. Apart from metabolic disorders the risk of stone formation is also influenced by a low inhibitor activity in urine. Though some aspects in the pathogenesis of urolithiasis remain uncertain, the exact knowlege of important aetiological factors of stone formation is the basis of correct treatment and the prevention of recurrence of urinary calculi.
Wiener klinische Wochenschrift 09/1979; 91(15):503-9. · 0.81 Impact Factor
