Nancy Doring

Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada

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Publications (2)1.8 Total impact

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    ABSTRACT: Assessment of nutritional status in children with cancer is important but measures based on weight can be problematic at diagnosis, especially in those with advanced disease. Likewise, dual energy x-ray absorptiometry may be confounded by other radiological procedures and is not commonly available in low-income countries where most children with cancer live. Arm anthropometry is not subject to these constraints. In a study sample of 99 Canadian patients with cancer at diagnosis, mid-upper arm circumference correlated well with lean body mass as measured by dual energy x-ray absorptiometry but triceps skin fold thickness was a poor predictor of fat mass. Arm anthropometry can be a useful tool for the measurement of nutritional status in children with cancer. However, further studies, particularly in low-income countries and in children with solid tumors at diagnosis, are required to determine the full extent of its utility.
    Journal of Pediatric Hematology/Oncology 03/2011; 33(3):e101-4. DOI:10.1097/MPH.0b013e3182002a65 · 0.90 Impact Factor
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    ABSTRACT: The nutritional status of children with cancer is clinically important. In an effort to separate the influences of disease and treatment, we studied children at the time of diagnosis. A total of 99 children underwent assessment by 24 hours dietary recall, measurement of body mass index (BMI), and analysis of body composition by dual energy x-ray absorptiometry (DXA scan). The group averages for calorie intake and BMI were close to the median population norms but ranged widely among individuals. As a group the study participants exceeded the Dietary Reference Intake for protein. Nine children (9%) had a BMI <fifth percentile. There were statistically significant but at best moderate correlations between dietary intake and body composition by DXA scan. Twenty-four hours dietary recall may not provide accurate assessment of nutritional status in individual children with cancer at diagnosis. However, DXA scans cannot be undertaken in a timely fashion on all children at this point. Alternative methods of assessment are being explored.
    Journal of Pediatric Hematology/Oncology 10/2010; 32(8):e299-303. DOI:10.1097/MPH.0b013e3181e9e43c · 0.90 Impact Factor