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ABSTRACT: Ten cases of acute febrile neutrophilic dermatosis or Sweet's disease have been studied clinically and histologically. Seventy percent of the patients were females with mean age of 43.1 +/-9 years. All of them presented the typical skin lesions consisting of papules and painful erythematous--edematous plaques in face, neck and upper chest. Fever was observed in seven patients and painful joints in four cases. One case presented polyarthritis of the big joints and there was one other case of conjuntivitis. The analytical data revealed a constant increase in sedimentation rate observed in 90% of patients. Leukocytosis was observed in 30% of patients and neutrophilia in 40%. Histologically, the lesions showed a neutrophilic infiltration of the skin without signs of vasculitis. Eight patients received treatment with Prednisone per os, one of whom, because of his relapses, was later given Potassium Iodine. Another patient was treated with Indomethacin, and one patient did not received any treatment. The evolution was favorable in all cases with sustained remissions. Sweet's Syndrome has been described associated mainly with acute myeloid leukemia in 10-20% of patients and in isolated instances with other systemic and neoplasic diseases. The concomitant conditions in 50% of our cases were: Ulcerative colitis, nodular sclerotic Hodgkin disease, infiltrative ductal carcinoma of the breast, carcinoma of the uterus neck and Crohn's disease; these last two associations had not been previously described in the literature.
Revista Clínica Española 05/1990; 186(6):264-9. · 2.01 Impact Factor
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Revista Clínica Española 04/1990; 186(5):241. · 2.01 Impact Factor
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Revista Clínica Española 04/1989; 184(4):212-4. · 2.01 Impact Factor
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Revista Clínica Española 11/1988; 183(5):279-80. · 2.01 Impact Factor
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ABSTRACT: We report two cases of cutis marmorata telangiectatica congenita (CMTC) a rare vascular anomaly which is manifested by a reticulate vascular pattern at birth. We comment the clinical aspects and review the previous reports.
Medicina cutánea ibero-latino-americana 02/1988; 16(5):393-6.
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Medicina cutánea ibero-latino-americana 02/1988; 16(5):430-1.
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Medicina cutánea ibero-latino-americana 02/1988; 16(5):431-2.
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ABSTRACT: We report a new case of localized Darier's disease or keratosis follicularis with successful response to topical retinoic acid treatment. We comment the clinical histopathological features and differential diagnosis of these uncommon variant which has only been reported in 10% of the patients.
Medicina cutánea ibero-latino-americana 02/1988; 16(2):161-3.
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Revista Clínica Española 12/1987; 181(8):410-2. · 2.01 Impact Factor
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Revista Clínica Española 04/1987; 180(4):209-13. · 2.01 Impact Factor
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ABSTRACT: Acquired digital fibrokeratomas are uncommon benign fibrous tumors frequently situated on fingers. Histopathologic findings include an acanthotic hyperkeratotic epidermal envelope that surrounds a core of normal appearing connective tissue. Clinical, histopathological aspects and differential diagnosis are discussed.
Medicina cutánea ibero-latino-americana 02/1987; 15(4):337-40.
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Anales espanoles de pediatria 01/1986; 23(8):605-8.
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Archives of Dermatology 11/1985; 121(10):1242. · 3.89 Impact Factor
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Revista Clínica Española 10/1985; 177(4):175-80. · 2.01 Impact Factor
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Revista Clínica Española 06/1985; 176(9):476-8. · 2.01 Impact Factor
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Revista Clínica Española 05/1984; 173(2):129-32. · 2.01 Impact Factor
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Revista Clínica Española 04/1984; 172(6):311-3. · 2.01 Impact Factor
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ABSTRACT: A case of congenital cutaneous candidiasis is reported. This is a rare infection of the new born, which is usually benign and autolimited unless it becomes generalized. Laboratory data which allows the differentiation of this disease from others clinically similars and the relevant literature are reviewed.
Medicina cutánea ibero-latino-americana 02/1984; 12(3):269-72.
