Publications (1)3.7 Total impact
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Article: Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer.
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ABSTRACT: Peptide thioesters are important tools for protein synthesis and semi-synthesis through their use in Native Chemical Ligation (NCL). NCL can be employed to assemble site-specifically modified proteins that can help elucidate the mechanisms of biomolecular processes. In this article we explore the compatibility of phosphopeptide synthesis and glycopeptide synthesis with thioester production through N→S acyl transfer.Organic & Biomolecular Chemistry 11/2010; 8(22):5113-9. · 3.70 Impact Factor
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2010
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University College London
- Department of Chemistry
London, ENG, United Kingdom
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