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Publications (2)2.14 Total impact

  • Hui Zheng · Song Xue · Zhen-Lei Hu · Jiang-Gui Shan · Wen-Gang Yang ·
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    ABSTRACT: There is no agreement on whether statins influence the incidence of atrial fibrillation after coronary artery bypass grafting. We performed a meta-analysis of 12 studies that compared statins with controls. Statin therapy significantly reduced the incidence of postoperative atrial fibrillation (odds ratio, 0.50; 95% confidence interval (CI), 0.35-0.73) and length of hospital stay (weighted mean difference, -0.72; 95% CI, -0.99 to -0.45), an effect that survived detailed subgroup analysis. Meta-regression analysis revealed that patient characteristics did not influence the extent of improvement in the incidence of postoperative atrial fibrillation attributable to statins. In conclusion, patients undergoing coronary artery bypass grafting benefit from perioperative treatment with statins, which significantly reduce the incidence of postoperative atrial fibrillation and length of hospital stay.
    Journal of cardiovascular pharmacology 04/2014; 64(3). DOI:10.1097/FJC.0000000000000102 · 2.14 Impact Factor
  • Jiang-Gui Shan · Song Xue · Gen-Xing Xu · Wei-Jun Wang · Feng Lian · Sha Liu · Zhen-Lei Hu · Ri-Tai Huang ·
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    ABSTRACT: To explore the effect of acupuncture-drug compound anesthesia on immune function in patients with extracorporeal circulation undergoing cardiac surgery. Thirty cases undergoing cardiac surgery which included atrial septal defect neoplasty, ventricular septal defect neoplasty, mitral valve replacement and pulmonary valve coarctotomy were randomly divided into group A and group B, 15 cases in each group. Group A was given general anesthesia plus acupuncture at Neiguan (PC 6), Lieque (LU 7) and Yunmen (LU 2), and group B was given simple general anesthesia. Tumor necrosis factor-alpha (TNF-alpha), interleukin-2 (IL-2) and interleukin-10 (IL-10) levels before and after surgery were compared. The level of TNF-alpha was increased and the levels of IL-2 and IL-10 in the serum were decreased in both groups after extracorporeal circulation for 2 h and 24 h, and the ranges of all changes were more less in group A (all P < 0.05). Compared with simple general anesthesia, acupuncture-drug compound anesthesia can improve immune suppression partially in the perioperative periods under the same conditions of controlling anesthesia degree.
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion 07/2010; 30(7):585-8.