James Provenzale

Publications (7)4.43 Total impact

• Article: Diffusion tensor imaging for evaluation of the childhood brain and pediatric white matter disorders.

  Jared Isaacson, James Provenzale
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  ABSTRACT: Magnetic resonance (MR) imaging has been used by investigators and clinicians to assess the development of the brain in childhood to understand both patterns of normal growth and patterns by which a maturing brain may deviate from normal. Advanced MR techniques such as diffusion tensor imaging (DTI) have gained prominence as a means of assessing brain development. This review explains the sequence of brain maturation and the means by which DTI can be used to assess it in normal children.
  Neuroimaging Clinics of North America 02/2011; 21(1):179-89, ix. · 1.51 Impact Factor
• Article: Frequency of various brain parenchymal findings of early cerebral ischemia on unenhanced CT scans.

  Basar Sarikaya, James Provenzale
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  ABSTRACT: The purpose of the study was to determine the frequency of various unenhanced computed tomography (CT) findings of early cerebral ischemia within brain parenchyma, which could be useful to the radiologist who is interpreting CT studies by indicating the CT finding that is most likely to be present in early cerebral ischemia. We analyzed articles reporting the use of unenhanced CT in acute cerebral ischemia over the period 1976-2009 for frequency of the following brain parenchyma signs: loss of insular ribbon, obscuration of lentiform nucleus, sulcal effacement, and parenchymal hypodensity. We recorded data for the 2-, 3-, 6-, and 12-h intervals after symptom onset from various studies and (1) calculated percent of time intervals in which >50% of patients exhibited the finding in any study and (2) pooled results for patients reported as having a specific CT finding during a specific time interval. We hypothesized that CT findings indicating brain swelling, which would be expected to be a relatively late phenomenon, would be detected at a lower rate in the first 6 h than changes of decreased density of brain tissue and increased density of arteries. The loss of insular ribbon sign (83% of time intervals reported) and obscuration of lentiform nucleus sign (75%) were the most common signs present in >50% patients in a time interval in any article. Pooled results showed that the two most common findings in the first few hours were loss of insular ribbon (70% at 2 h; 77% at 3 h) and obscuration of lentiform nucleus (60% at 2 h; 82% at 3 h). At 6 h, parenchymal hypodensity (53%), loss of insular ribbon (46%), and obscuration of lentiform nucleus (46%) were most common, which validated our hypothesis. At 12 h, loss of insular ribbon (65%) and sulcal effacement (63%) were most common. Loss of insular ribbon and obscuration of lentiform nucleus appear to be the most common signs of early cerebral ischemia identified on unenhanced CT.
  Emergency Radiology 05/2010; 17(5):381-90.
• Article: CT evaluation of subarachnoid hemorrhage: a practical review for the radiologist interpreting emergency room studies.

  James M Provenzale, Lotfi Hacein-Bey
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  ABSTRACT: Radiologists working in an emergency radiology setting frequently interpret computed tomography (CT) studies of patients with suspected subarachnoid hemorrhage (SAH). This article reviews the sensitivity of CT for detection of SAH, some major patterns of SAH related to a ruptured aneurysm, and the differential diagnosis of SAH not due to aneurysmal rupture.
  Emergency Radiology 07/2009; 16(6):441-51.
• Article: MRI and MRA for evaluation of dissection of craniocerebral arteries: lessons from the medical literature.

  James M Provenzale
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  ABSTRACT: MR imaging and MR angiography have become first-line imaging techniques in assessment of the patient with suspected dissection of the carotid and vertebral arteries. This review describes the advantages of these two techniques for diagnosis and describes diagnostic pitfalls.
  Emergency Radiology 11/2008; 16(3):185-93.
• Article: Acute stroke imaging research roadmap.

  Max Wintermark, Gregory W Albers, Andrei V Alexandrov, Jeffry R Alger, Roland Bammer, Jean-Claude Baron, Stephen Davis, Bart M Demaerschalk, Colin P Derdeyn, Geoffrey A Donnan, [......], David S Liebeskind, Leif Ostergaard, William J Powers, James Provenzale, Peter Schellinger, Robert Silbergleit, Alma Gregory Sorensen, Joanna Wardlaw, Ona Wu, Steven Warach
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  ABSTRACT: The recent "Advanced Neuroimaging for Acute Stroke Treatment" meeting on September 7 and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, emergency physicians, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), industry representatives, and members of the US Food and Drug Administration (FDA) to discuss the role of advanced neuroimaging in acute stroke treatment. The goals of the meeting were to assess state-of-the-art practice in terms of acute stroke imaging research and to propose specific recommendations regarding: (1) the standardization of perfusion and penumbral imaging techniques, (2) the validation of the accuracy and clinical utility of imaging markers of the ischemic penumbra, (3) the validation of imaging biomarkers relevant to clinical outcomes, and (4) the creation of a central repository to achieve these goals. The present article summarizes these recommendations and examines practical steps to achieve them.
  American Journal of Neuroradiology 06/2008; 29(5):e23-30. · 2.93 Impact Factor
• Article: CT and MR imaging of acute cranial trauma.

  James Provenzale
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  ABSTRACT: A wide variety of imaging findings can be seen in the setting of acute head trauma. The purpose of this manuscript is to review the major computed tomography and magnetic resonance imaging findings of various types of traumatic head injuries with the intent of providing the reader with a means to diagnose these lesions quickly and accurately.
  Emergency Radiology 05/2007; 14(1):1-12.
• Article: MR imaging of spinal trauma.

  James Provenzale
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  ABSTRACT: Magnetic resonance (MR) imaging plays an increasingly important role in evaluation of the patient who has sustained spinal trauma. This review discusses the role of MR imaging relative to plain radiographs and computed tomography in the evaluation of the patient with spinal trauma and presents a method for systematic review of MR images for assessing spinal injury.
  Emergency Radiology 04/2007; 13(6):289-97.