Hong-Der Tsai

Publications (1)3.97 Total impact

• Source

  Available from: Jyuer-Ger Yang

  Article: Androgen excess down-regulates connexin43 in a human granulosa cell line.

  Cheng-Hsuan Wu, Jyuer-Ger Yang, Jiann-Jou Yang, Yueh-Min Lin, Hong-Der Tsai, Ching-Yuang Lin, Pao-Lin Kuo
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  ABSTRACT: By use of a cell model, we found that high levels of androgen reduce connexin43 expression and impair gap junction intercellular communication between human granulosa cells through the androgen receptors. High levels of androgen may impair folliculogenesis and in turn lead to ovulatory dysfunction in polycystic ovary syndrome patients.
  Fertility and sterility 12/2010; 94(7):2938-41. · 3.97 Impact Factor