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Ceska gynekologie / Ceska lekarska spolecnost J. Ev. Purkyne 07/1995; 60(3):160-2.
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ABSTRACT: A rare case of extragenital carcinoma metastatic to endometrium was described. Diagnosis of primary mammary lobular carcinoma was established from curettment.
Ceskoslovenska patologie 03/1995; 31(1):31-2.
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ABSTRACT: Bronchopulmonary dysplasia is a most frequent contemporary lesion of the lung in early childhood. It is characterized by clinical symptoms (neonatal respiratory distress syndrome) and by X-ray picture reflecting progressive morphological changes in the respiratory tract, i.e. in trachea, bronchi, bronchioles, and pulmonary acini, followed by interstitial pulmonary lesion. As usual, bronchopulmonary dysplasia is forerun by hyaline membranes and may be associated with or followed by interstitial emphysema. Pathogenetic participants are toxicity of highly concentrated and long administered oxygen, artificial mechanical ventilation with an intermittently positive pressure, barotrauma first of immature lung causing emphysema and pneumothorax and pneumomediastinum, lung edema, shortage of A and E vitamins and ceruloplasmin deficiency. Morphological changes in bronchopulmonary dysplasia are alike diffuse alveolar damage in bigger children or adults. Nevertheless, neonatal changes differ from later pulmonary lesion by evolving in an immature tissue and by being complicated with necrotizing "obstructive" bronchiolitis.
Ceskoslovenska patologie 05/1993; 29(2):45-51.
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ABSTRACT: Aggressive angiomyxoma of pelvis and perineum was identified in two women (of 31 and 53). Its site was in the right fossa ischiorectalis and vulva. There was not observed any relaps in 60 and/or 9 months after surgery. Amorphous tumour mass was soft with finger-like projections. Spindle and starshaped tumour cells were spread in a loose edematous myxoid vascularized stroma; they had a benign character lacking of mitoses and nuclear atypia. Myxoid stroma could be stained rather faintly with Alcian blue at pH 1. Dilated capillaries, veins and arterioles were a substantial component of the tumour. Nerve and muscle fibres and their fragments were included here and there in the tumour. Tumour cells had a fibroblast ultrastructure which was supported by immunohistology. Discussion comprised differential diagnosis of myxoma, myxoid liposarcoma and myxoid type malignant fibrous histiocytoma among others.
Ceskoslovenska patologie 04/1991; 27(1-2):26-32.
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ABSTRACT: A retrospective analysis of 919 consecutive cervical biopsies from the year 1987 showed three different types of lesion--unspecified lymphocytic endocervicitis, herpetic changes and coilocytic changes. Attention was concentrated on their histo-cytologic picture as well as on a coincidence of dysplasia and collocytosis.
Ceskoslovenska patologie 12/1989; 25(4):217-25.
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ABSTRACT: A group of 2,576 autopsies of children of the age of 0 to 15 years (made between 1978 and 1987) comprised 14 congenital (neonatal) tumours (among 93 tumorous lesions). Teratomas were the most frequent congenital tumours followed by neuroblastomas (4 and 3 cases). Neuroblastomas grew from cervical and thoracoabdominal sympathicus and from the right adrenal medulla. The most frequent and most extent hematogenic dissemination concerned liver, microscopical examination found dissemination in various organs as well as a lymphatic spread to regional lymph nodes (in 2 cases). One case was characterized by an exclusive continual destructive growth in retroperitoneum and posterior mediastinum with 2 macroscopical secondaries in skeleton. Pathognomic differentiated structures were always found by light microscopy. Differential diagnosis of round cell tumours of infancy was discussed with a concise exposure of symptomatology and autoptic findings of neuroblastomas according to congenital cases from literature.
Ceskoslovenska patologie 09/1989; 25(3):160-6.
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ABSTRACT: A total of 7017 women were examined during a year in a specialized dispensary for prevention of cervical cancer and in a department of obstetrics. Diagnosis of PAP III or higher was established in 227 smears, i.e. 3,3% of cases. A correlation of positive cytology with following biopsy was performed. The influence of cervical inflammation and virus lesion on possible modification of suspect cytology was discussed.
Ceskoslovenska patologie 09/1984; 20(3):151-60.
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ABSTRACT: The technology of fine-needle aspiration of prostatic tissue was described and its results discussed in a group of 45 patients. Demonstration of findings included: normal cytology, adenomyomatous hyperplasia with mosaic pattern of epithelial cells, acute purulent inflammation, chronic inflammation with pseudoxanthomatous lipophages , seminal vesicles with atypical non-cohesive epithelial cells, and neoplasia.
Ceskoslovenska patologie 06/1984; 20(2):79-84.
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ABSTRACT: Detailed examination of 26 pleural exudations by transmissive and scanning electron microscopy gave new cytodiagnostical possibilities. In addition to confirming the light-microscopical criteria of malignancy transmissive electron microscopy characterized the cells of adenocarcinoma by microvilli with common structure, various length, irregular orientation and crossing over or branching. They tend to be a bit widened at their base or top and to cover all the surface of cells. Microvilli in the neighbouring parts of cells are less numerous, irregularly oriented, shortened and interdigitating. Not even here is the surface of carcinoma cells quite smoth in contrast to neighbouring mesotelial cells. Scanning electron-microscopical examination being neither technologically sophisticated nor time consuming enables a scope on cellular surfaces uniformly covered by countless microvilli densely distributed.
Ceskoslovenska patologie 12/1982; 18(4):207-14.
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ABSTRACT: Detailed examination of 48 pleural exudations showed that a sequence of morphological changes [desquamation, proliferation, activation, degeneration] was a uniform response of mesothelium to various pathological stimuli. Desquamated mesothelial cells grow round and bigger, their nuclei increase, multiply, become irregular and get a coarse chromatin pattern. Their cytoplasm is less often homogeneous, a bit basophil and mostly vacuolized to some extent; fusion of vacuoles can lead to a signet-ring appearance. Provided that highly activated mesothelial cells phagocytize foreign corpuscular material, they cannot be distinguished from the macrophages. Their cytoplasmic organelles multiply progressively. More frequent lysosomes occur sometimes with dense lamellated myelin-like bodies. Glycogen particles increase in number substantially in peripheric cytoplasmic zone. Tonofilaments are very conspicuous, arranged round the nucleus, but disappear during progressive mesothelial activation and degradation. Numerous microvilli are gradually reduced in number, change into voluminous plasmatic blebs, and finally, mesothelial surface grow irregular or smooth. In dubious cases, electron microscopy [transmissive and scanning] gives more precise features of organelles and surface structures in activated mesothelial cells and helps to differentiate them from other exudation cells especially the neoplastic ones.
Ceskoslovenska patologie 12/1982; 18(4):193-206.
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Ceskoslovenská gynekologie 02/1980; 45(10):724-6.
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ABSTRACT: Referring to their group of 325 patients examined by means of all-around endobronchial biopsy material withdrawal the authors present the results of cytological and histological diagnosis. Endobronchially material obtained by direct aspiration of bronchial secretions, by wash-outs, and by catheterization and brush biopsy represents, particularly in peripheral localizations, a significant and often decisive contribution to the objectivization of malignant affections. The authors present and discuss morphological criteria of malignity derived from endobronchially obtained material processed by the method of cytoblocks stressing, at the same time, the possibility of an accurate localization of the pathological process down to the particular segment involved.
Ceskoslovenska patologie 12/1979; 15(4):173-8.
