Publications (12)11.11 Total impact
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Article: Does a fitted abdominal corset makes colonoscopy more tolerable?
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ABSTRACT: The present study evaluated the usefulness of a fitted abdominal corset for colonoscopy, enabling proper compression of the abdomen during the entire examination. Patients undergoing colonoscopy were subjected to either traditional methods or to using a fitted abdominal corset. Two hundred and sixteen patients were divided into two groups: group 1 (conventional colonoscopy) and group 2 (colonoscopy with abdominal corset). Cecal intubation rate and time need for manual compression and change of position were recorded. At the end of each colonoscopic examination, the patient evaluated pain by an 11-point visual analog scale from 0 to 10 (0: no pain, 10: worst pain). Cecal intubation time was shorter, the need for extra manual compression and change of position decreased and patients felt less pain during the procedure as denoted by lower visual analog scale scores in the group using a fitted abdominal corset, when compared to the group without a corset, in a statistically proven manner. Our data confirm the usefulness of the abdominal corset in decreasing the degree of patient pain and it makes colonoscopy easier and quicker with less manipulation, so we propose using a fitted abdominal corset during routine colonoscopic procedures.Digestive Endoscopy 05/2012; 24(3):164-7. · 1.19 Impact Factor -
Article: New and Simple Approach for Preventing Postoperative Peritoneal Adhesions: Do not Touch the Peritoneum without Viscous Liquid-A Multivariate Analysis.
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ABSTRACT: Background. Postoperative peritoneal adhesions (PPAs) are an unsolved and serious problem in abdominal surgery. Method. Viscous liquids of soybean oil, octyl methoxycinnamate, flax oil, aloe vera gel, and glycerol were used in five experiments, using the same methodology for each. Liquids were applied in the peritoneal cavity before and after mechanical peritoneal trauma. Results were evaluated by multivariate analysis. Results. Compared with the control group, macroscopic and microscopic adhesion values before (P < .001) and after (P < .05) application of viscous liquids significantly reduced PPAs. Values were significantly lower when liquids were applied before rather than after peritoneal trauma (P < .0001). Discussion. Viscous liquids injected into the peritoneal cavity before or after mechanical peritoneal trauma decrease PPA. Injection before trauma was more effective than after trauma. In surgical practice, PPA formation may be prevented or decreased by covering the peritoneal cavity with an appropriate viscous liquid before abdominal surgery.Obstetrics and Gynecology International 01/2012; 2012:368924. -
Article: Comparative outcomes of antireflux treatment for laryngopharyngeal reflux symptoms and upper abdominal symptoms in patients with endoscopic esophagitis.
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ABSTRACT: The objectives of this prospective study are to determine the prevalence of laryngopharyngeal reflux (LPR) symptoms in patients with endoscopic esophagitis, to investigate the relationship between LPR symptoms and upper abdominal symptoms of gastroesophageal reflux disease (GERD) and to compare the treatment responses of both symptom groups. 120 consecutive patients having complaints of GERD were included. Group I consisted of 62 patients with a diagnosis of endoscopic esophagitis. The second group consisted of 58 subjects with no detectable pathology at gastroscopy. LPR symptoms and upper abdominal symptoms were graded. Proton pump inhibitors (PPI) were prescribed to patients. Both groups of symptoms were compared in two groups of patients. The improvement in symptoms was evaluated after treatment. The frequencies of LPR symptoms were statistically higher in patients with endoscopic esophagitis. All LPR symptoms were statistically relieved in their frequency after treatment. The decrease in LPR symptom scores after treatment in group I was statistically significant. FSSG (frequency scale for the symptoms of GERD) scores were statistically higher in group I than in group II before treatment. After treatment, FSSG scores were significantly decreased in group I. There was statistically significant positive correlation between the LPR symptom scores and FSSG scores before treatment. In conclusion, there is a high incidence of LPR symptoms and upper abdominal symptoms in patients with endoscopic esophagitis. LPR and upper abdominal symptoms responded well to antireflux treatment in patients with endoscopic esophagitis.Archives of Oto-Rhino-Laryngology 05/2011; 268(5):703-8. · 1.29 Impact Factor -
Article: Type of lateral internal sphincterotomy incision: parallel or vertical?
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ABSTRACT: The lateral internal sphincterotomy (LIS) technique is considered the optimal surgical treatment for chronic anal fissures (CAFs), although questions remain regarding the best technique. The present study investigated whether the type of anoderm incision (vertical or parallel to the anus) affects wound healing, wound-related complications, incontinence, and recurrence rates in CAF patients undergoing open LIS. This prospective randomized clinical study divided 52 patients undergoing LIS for CAF into two groups. In group 1 (n=25) the incision was made vertical to the anus; and in group 2 (n=27) it was made parallel to the anus. Incision sites were not sutured in either group. Wound site complications, wound healing times, perianal itching, incontinence, and recurrence rates were evaluated. Complications involving bleeding, hematoma, abscess formation, or fistulization were not observed in either group. Complications were observed in 5 patients of group 1 (1 wound infection, 1 ecchymosis, 2 flatus incontinence, 1 recurrence) and in three patients of group 2 (2 wound infections, 1 flatus incontinence). Overall wound complication, incontinence, and recurrence rates were 7.7, 5.8, and 1.9%, respectively. The two groups did not differ significantly in terms of wound complications, incontinence, or recurrence. Itching duration was significantly longer in group 1 (p<0.0001) Complete wound healing was slower in group 1 than group 2 (19.44±6.82 vs. 10.59±3.48 days, p<0.0001). Wound healing time and perianal itching duration were significantly reduced when anoderm incisions were made parallel to the anus compared to those made vertical to the anus.World Journal of Surgery 03/2011; 35(5):1137-41. · 2.36 Impact Factor -
Article: Laparoscopic cholecystectomy on the bikini line for invisible scar.
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ABSTRACT: A traditional laparoscopic cholecystectomy uses 4 trocar incisions on the upper abdomen, which may be the source of undesirable cosmetic outcomes. We describe here a modification of the traditional laparoscopic cholecystectomy by which scars remain underwear. Supplemental Digital Content 1, http://links.lww.com/SLE/A27. A 32-year-old woman and 43-year-old man with symptomatic cholelithiasis were chosen for laparoscopic cholecystectomy on the bikini line. Four trocar were used, all of them were positioned at the lower abdomen in the same parallel on the bikini line. All procedure was performed with standart laparoscopic instrumentation. Gallbladder was removed through the median suprapubical trocar site. Both procedures were technically successful with no skin incisions outside the bikini line. The total operation times were: 65 and 45 minutes, and the hospital stay were 2 days. There were no complications during or after surgery. We left no scar on the upper abdomen. Laparoscopic cholecystectomy on the bikini line is technically feasible, safe, and effective. There is no need for learning curve and extralaparoscopic instrumentation. The major advantage of this method is improved cosmetic outcome with no visible abdominal scars. This new technique carries the potential to be an option for the traditional laparoscopic cholecystectomy.Surgical laparoscopy, endoscopy & percutaneous techniques 02/2011; 21(1):e7-e10. · 1.23 Impact Factor -
Article: Histopathological changes of rat kidney with exposure to chronic thinner inhalation.
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ABSTRACT: Organic solvents are liquid substances commonly used in everyday life at home and in industrial workplaces. These solvents are found primarily in paint as thinner. Because other narcotics are hard to find, thinner is used as a narcotic especially among youngsters of low socioeconomic level. The aim of this study is to determine the histopathological changes of rat kidney with exposure to chronic thinner inhalation. Randomized trial--the study was conducted at the animal care facility of Haydarpasa Numune Education and Research Hospital. Forty albino Wistar male rats were used throughout the experiment. Three groups of rats inhaled thinner in a glass cage for 1, 3, and 5 weeks, respectively. Ten rats inhaled only the air in the room as the control group. We observed the development of inflammation in the kidneys that became more remarkable as exposure time extended. Development of inflammation because of thinner apparently differed between the groups of week 1 and week 5. There was no difference in granuloma development. If the experiment lasted longer, there might have been granuloma development. Based on histopathological evaluations, it was shown that exposure to chronic thinner inhalation causes detectable damage on the kidney, which becomes more prominent as exposure period extends. As we established disorders in movement and consciousness in the rats during thinner inhalation, we can conclude that thinner also has a damaging effect upon the central nervous system.Renal Failure 01/2011; 33(1):15-8. · 0.82 Impact Factor -
Article: Effects of contractubex on the prevention of postoperative peritoneal adhesion.
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ABSTRACT: There are numerus techniques and agents in use for reducing peritoneal adhesion formation. But in this research we believe this is the first research to reveal that contractubex (allium cepae, sodium heparin, and allantoin mixture) is reducing formed peritoneal adhesions. So it may be used to reduce the number of re-laparotomies/re-laparoscopies caused by peritoneal adhesions related complications. To evaluate the effects of contractubex (CT) in a rat model of postoperative peritoneal adhesion (PPA). Fifty rats were divided into four equal groups. In group 1, 1 g of CT was injected into the peritoneal cavity. In group 2, adhesions were generated. In group 3, adhesions were generated, and 1 g of CT was immediately applied into the peritoneal cavity. In group 4, adhesions were generated, and at postoperative d 7, 1 g of CT was applied into the peritoneal cavity. In group 5, adhesions were generated, and at postoperative d1, 3, 5, and 7, 1 g of CT was applied into the peritoneal cavity. The adhesions were scored both macroscopically and microscopically. The mean macroscopic adhesion scores in groups 1-5 were 0 ± 0, 2.9 ± 0.21, 2.3 ± 0.54, 0.8 ± 0.63, and 2.2 ± 0.72, respectively (P < 0.0001); the mean microscopic values were 0 ± 0, 2.8 ± 0.42, 2.8 ± 0.42, 0.6 ± 0.52, and 2.3 ± 0.48, respectively (P < 0.0001). The mean macroscopic adhesion score in group 4 was lower than that in group 2 (P = 0.001). The mean macroscopic adhesion scores in groups 3 and 5 were higher than those in group 4 (P = 0.045 and P = 0.038, respectively) but did not significantly differ from those in group 2 (P = 0.171 and P = 0.124, respectively). A single dose of contractubex did not prevent PPA formation but did diminish the amount of formed PPAs.Journal of Surgical Research 12/2010; 164(2):193-7. · 2.25 Impact Factor -
Article: A new approach to postoperative peritoneal adhesions: prevention of peritoneal trauma by aloe vera gel.
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ABSTRACT: Covering peritoneal surfaces with aloe vera gel may prevent peritoneal trauma and hence postoperative peritoneal adhesions. Forty Wistar albino out-bred female rats (mean weight, 180+/-25 g; mean age, 6 months) were divided into four groups. In Group 1, 0.1 mL aloe vera gel was injected into the peritoneal cavities. In Group 2, peritoneal adhesions were induced. In Group 3, adhesions were induced and the modeled area was covered by 0.1 mL aloe vera gel. In Group 4, the area was covered with aloe vera gel prior to adhesion induction. The rats were sacrificed on postoperative day 10 and the adhesions were scored both microscopically and macroscopically. The mean macroscopic adhesion score in the four groups was 0, 5.8+/-0.42, 5.2+/-0.79, and 1.1+/-1.2 respectively, with the difference between Group 4 and Groups 2 (p<0.001) and 3 (p<0.05) statistically significant. The mean histopathological fibrosis values were significantly higher in Group 3 than in Group 4 (2.6+/-0.51 vs 1.2+/-0.91, p=0.002). Aloe vera gel can effectively decrease adhesion formation if applied before, but not after, after peritoneal trauma. This effect is likely due not to its chemical properties but to its viscosity, providing a covering to prevent peritoneal trauma.European journal of obstetrics, gynecology, and reproductive biology 04/2010; 149(2):195-8. · 1.97 Impact Factor -
Article: Ability of the ankaferd blood stopper® to prevent parenchymal bleeding in an experimental hepatic trauma model.
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ABSTRACT: Hepatic parenchymal bleeding (HPB) is a major problem following both trauma and elective hepatic procedures. The present study investigated the effect of the Ankaferd Blood Stopper® (ABS) on HPB. Method(s): A total of 20 rats were used. After creating a laceration model in the left lateral hepatic lobe, the area was compressed for 3 minutes with the ABS in the rats in group 1 (n=10) and with 0.9% NaCl-soaked gauze in the rats in group 2 (n=10). RESULTS: The mean change in haematocrit levels between baseline and the 24 hour values in group 1 was lower than group 2 (p=0.045). The mean perioperative bleeding in group 1 was lower than group 2 (p=0.003). The histopa-thologic evaluation revealed that there were no differences between the groups with respect to areas of necrosis (p=0.107) or inflammation (p=0.135). CONCLUSION: Although the ABS does not stop HPB completely, it ensures a statistically significant reduction in HPB.International journal of clinical and experimental medicine 01/2010; 3(3):186-91. -
Article: A novel colonic anastomosis technique involving fixed polyglycolic acid mesh.
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ABSTRACT: Polyglycolic acid mesh (PAM) reinforcement of colonic anastomoses were evaluated. Twenty female albino rabbits were divided into two groups. Each rabbit underwent segmental colonic resection with single-layer anastomosis. In one group of rabbits, PAM of length equal to the circumference of the anastomosis was applied. Rabbits were sacrificed on postoperative day 10 and peritoneal adhesions, anastomosis burst pressure, and anastomosis histopathological characteristics were evaluated. The average burst pressure for the control and PAM groups was 149±15.95 mmHgand 224±124.5 mmHg, respectively (p=0.578). All control anastomoses burst, whereas only five (50%) PAM anastomoses burst (p<0.03). There was no anastomotic leakage in the control group, whereas three PAM group anastomoses leaked (p=0.210). The collagen fiber density and amount of neovascularization were lower in the PAM than the control group (p=0.001 and p=0.002, respectively). The average peritoneal adhesion value was 1.6±0.51 in the control group and 2.9±0.31 in the PAM group (p<0.0001). The new fixed PAM-reinforced anastomosis technique resulted in an increased risk of anastomosis leakage and peritoneal adhesion, but also higher in non-burst anastomoses.International journal of clinical and experimental medicine 01/2010; 3(4):341-6. -
Article: Torsion of a giant pedunculated liver hemangioma mimicking acute appendicitis: a case report.
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ABSTRACT: Hemangiomas are the most common benign neoplasms affecting the liver. They occur at all ages. Most cases are asymptomatic and do not require any treatment. Rarely, hemangiomas can be pedunculated. If they undergo torsion and infarction, they become symptomatic. Herein; we report the case of a 31 year old male presenting with features of acute appendicitis: continuous right iliac fossa pain, rebound, guarding tenderness at McBurney' s point, nausea, anorexia, shifted white blood cell count and a Mantrels score of 6. At laparotomy a normal appendix was observed and a torsioned pedinculated liver hemangioma turned out to be the cause.World Journal of Emergency Surgery 01/2010; 5:2. -
Article: MALT lymphoma of the rectum, presenting with rectal prolapsus: a case report.
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ABSTRACT: Up to now, there have been only a few reported cases of Mucosa-associated lymphoid tissue (MALT) lymphomas arising in the rectum. Its clinical presentation is indistinguishable from that of rectal carcinoma but the treatment is apparently different. Symptoms of primary lymphomas involving the rectum include; anorexia, weight loss, change in bowel habits, obstruction, and bleeding. These symptoms are not disease specific and can be seen in many other gastrointestinal disorders. Patients with polypoid masses may present with obstruction symptoms. In this rare case, a female patient admitted to the emergency service with prolapsus of a rectal mass.The optimal treatment of rectal MALT lymphoma is not well defined yet, given the rarity of the disease. Surgical resection of the localized lesion and following adjuvant chemotherapy has proved to be an effective treatment option. However, a close and long-lasting follow-up is important.Cases Journal 01/2010; 3(1):33.
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2011
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Kanuni Sultan Süleyman Training and Research Hospital Istanbul
İstanbul, Istanbul, Turkey
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