ABSTRACT: Sarcoidosis of the central nervous system has been variously reported in 5-15% of all sarcoid patients. However, presentation of sarcoidosis as an isolated 'intracranial tumor' is rare. A 35-year-old African-American woman presented with intractable headaches. Neuroimaging revealed a tumor that was suggestive of a glioma or meningioma or metastasis. The symptoms did not respond to steroids, and an open biopsy of the lesion revealed non-caseating granuloma. A thorough work-up for systemic sarcoidosis was negative. The patient remains symptom-free at a 2-year follow-up. Primary sarcoid granuloma of the brain is rare. Once systemic disease has been excluded, early tissue diagnosis is crucial. This is particularly relevant for patients in the high-risk population before considering empirical radiosurgery.
Clinical Neurology and Neurosurgery 10/2002; 104(4):289-92. · 1.58 Impact Factor
The Journal of the Louisiana State Medical Society: official organ of the Louisiana State Medical Society 156(4):177-80.
The Journal of the Louisiana State Medical Society: official organ of the Louisiana State Medical Society 158(4):172-5.