Publications (10)12.87 Total impact
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Article: [Circumcision-induced penodynia].
Annales de Dermatologie et de Vénéréologie 08/2012; 139(8-9):566-7. · 0.72 Impact Factor -
Article: [The value of biopsy in the diagnosis of penile dermatoses].
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ABSTRACT: Penile biopsy can be useful to establish an accurate diagnosis when managing male genital dermatoses. We investigated the value of genital biopsy by comparing suspected clinical diagnosis with final histologic diagnosis. We retrospectively examined the clinical file of men with genital dermatoses undergoing genital biopsy. We collected details of age, biopsy site, suspected diagnosis after clinical examination and histologic diagnosis. One hundred and thirty-eight male patients were enrolled in the study. Their mean age was 52 years. Most biopsies (41%) were performed on the glans. Microscopic examination failed to rule out a diagnosis in 14.5% of the cases. It confirmed the clinically suspected diagnosis in 29.7% of cases and ruled out a particular diagnosis from among several clinical hypotheses in 26.8% of cases. The histological diagnosis had not been suspected in 18.1% of cases. Penile biopsy has an important role in the diagnosis of penile dermatoses. In our study, in 44.9% of cases, a clinically unsuspected diagnosis was identified or a differential diagnosis was resolved.Annales de Dermatologie et de Vénéréologie 08/2012; 139(8-9):521-5. · 0.72 Impact Factor -
Article: [Metastatic extramammary Paget's disease of the scrotum].
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ABSTRACT: Extra-mammary Paget's disease (EMPD) is currently considered a slowly progressing in situ adenocarcinoma. It is much more rarely associated with an invasive underlying adenocarcinoma than in mammary sites, where this association is almost always seen. However, an invasive course is to be feared where EMPD has been progressing for several years. A 59-year-old man consulted for treatment of scrotal Paget's disease present for over 15 years and treated with topical emollients alone. Two infiltrated areas had recently appeared and their excision led to a diagnosis of invasive Paget's disease at these two points. Metastasis occurred 10 months later and rapidly proved fatal. Until now, non-invasive EMPD has been considered a fairly non-aggressive disease due to its indolent progression. However, it is characterised by considerable risk of relapse following surgical excision, regardless of the surgical margin. Despite a good prognosis at the intraepithelial stage, the rising life expectancy of the population means a greater likelihood of an invasive course or of the appearance of an underlying adenocarcinoma, and management of this condition can thus no longer be neglected. The present clinical case underscores the need for closer surveillance of the disease as of the intraepithelial stage.Annales de Dermatologie et de Vénéréologie 05/2012; 139(5):387-90. · 0.72 Impact Factor -
Article: Adjuvant prophylactic regional radiotherapy versus observation in stage I Merkel cell carcinoma: a multicentric prospective randomized study.
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ABSTRACT: The treatment of stage I Merkel cell carcinoma (MCC) usually includes wide local excision (WLE) combined with irradiation of the tumor bed (ITB). No randomized study has ever been conducted in MCC. The purpose of this study was to assess the efficacy and safety of prophylactic adjuvant radiotherapy on the regional nodes. In this randomized open controlled study, patients for a stage I MCC treated by WLE and ITB were randomly assigned to regional adjuvant radiotherapy versus observation. Overall survival (OS) and probability of regional recurrence (PRR) were primary end points. Progression-free survival (PFS) and tolerance of irradiation were secondary end points. Eighty-three patients were included before premature interruption of the trial, due to a drop in the recruitment mainly due to the introduction of the sentinel node dissection in the management of MCC. No significant improvement in OS (P = 0.989) or PFS (P = 0.4) could be demonstrated after regional irradiation, which, however, significantly reduced the PRR (P = 0.007) with 16.7% regional recurrence rate in the observation arm versus 0% in the treatment arm. The treatment was well tolerated. The adjuvant regional irradiation significantly decreased the PRR in MCC, but benefit in survival could not be demonstrated.Annals of Oncology 07/2011; 23(4):1074-80. · 6.43 Impact Factor -
Article: [Guidelines for clinical practice: Standards, Options and Recommendations 2005 for the management of adult patients exhibiting an M0 cutaneous melanoma, full report. National Federation of Cancer Campaign Centers. French Dermatology Society. Update of the 1995 Consensus Conference and the 1998 Standards, Options, and Recommendations].
Annales de Dermatologie et de Vénéréologie 01/2006; 132(12 Pt 2):10S3-10S85. · 0.72 Impact Factor -
Article: [Single erythroplastic vulvar lesion in a 70-year-old woman: Bowen disease].
Annales de Dermatologie et de Vénéréologie 01/2002; 128(12):1361-2. · 0.72 Impact Factor -
Article: [Asymmetric vulvar pigmentation in a 51-year-old woman].
Annales de Dermatologie et de Vénéréologie 04/2001; 128(3 Pt 1):280-1. · 0.72 Impact Factor -
Article: [Vulvar intra-epithelial neoplasias].
Annales de Dermatologie et de Vénéréologie 132(6-7 Pt 1):576-83. · 0.72 Impact Factor -
Article: [Pigmented vulvar lesions].
Annales de Dermatologie et de Vénéréologie 133(8-9 Pt 1):717-23. · 0.72 Impact Factor -
Article: [Premalignant penile lesions].
Annales de Dermatologie et de Vénéréologie 137(6-7):486-92; quiz 485, 493-4. · 0.72 Impact Factor
Top co-authors
Top Journals
Institutions
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2012
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Assistance Publique – Hôpitaux de Paris
Paris, Ile-de-France, France -
Hôpital Saint-Louis – Hôpitaux universitaires "Sant-Louis, Laboisière, Fernand-Widal"
Paris, Ile-de-France, France
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