Alexandros Charonis

Harokopion University of Athens, Athínai, Attica, Greece

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Publications (3)4.24 Total impact

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    ABSTRACT: To determine the safety and efficacy of fresh, human sclera allografts as a patch graft material in glaucoma drainage device (GDD) surgery. Retrospective, noncomparative, interventional, consecutive case series. All GDD cases operated between 2008 and 2013 in which fresh human corneoscleral rims were used immediately after the central corneal button was used for penetrating or endothelial keratoplasty. Surgery was performed by 2 surgeons at 2 facilities. The Ahmed Glaucoma Valve (FP-7) was used exclusively in this cohort. Sixty-four eyes of 60 patients were identified; demographic data were recorded along with intraocular pressure (IOP), medication requirements, visual acuity, complications, and subsequent interventions. Incidence of complications. IOP and medication requirements at the last follow-up. Quilified success utilizing Tube Versus Trabeculectomy study criteria. The mean age of the cohort was 66.2±19.1 years; the average preoperative IOP was 33.2±11.1 mm Hg on 4.2±1.3 IOP-lowering agents before GDD surgery. IOP decreased significantly to 14.1±4.7 mm Hg (P<0.001) on 1.6±1.2 IOP-lowering agents (P<0.001) after an average follow-up of 18.2±15.4 months. There were no cases of early or late blebitis or endophthalmitis, and there was 1 case of conjunctival erosion and tube/plate exposure (1.6%) occurring 30 days after surgery. Qualified success was estimated as 90.5% and 81% at 1 and 2 years, respectively, using Tube Versus Trabeculectomy study criteria. Heterologous, fresh, human donor sclera appears to be a safe material for GDD tube coverage. It provides a cost-efficient alternative compared with traditional patch graft materials associated with a low risk of pathogen transmission.
    Journal of glaucoma 06/2015; DOI:10.1097/IJG.0000000000000294 · 2.11 Impact Factor
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    ABSTRACT: To report the acute and transient (within 10 days) presentation of vitreomacular traction following routine cataract surgery. This is a case series of 5 patients with no evidence of posterior vitreous detachment preoperatively who presented with acute vitreomacular traction following routine cataract surgery. All patients presented the first postoperative day with dramatically reduced visual acuity. The patients underwent optical coherence tomography and if necessary fundus fluorescein angiography. Images were suggestive of vitreomacular syndrome. In all 5 cases, there was spontaneous resolution of the traction within 10 days. The latter was probably related to the development of posterior vitreous detachment due to the uncomplicated cataract surgery. In 2 cases there were significant retinal pigment epithelium changes and decreased retinal thickness following the resolution of the traction leaving permanent metamorphopsia and slightly decreased visual acuity. Cataract-related acute vitreomacular traction is a rare phenomenon and not well-recognized; however, it resolves spontaneously within 10 days.
    European journal of ophthalmology 01/2011; 21(1):20-3. DOI:10.5301/EJO.2010.521 · 1.07 Impact Factor
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    ABSTRACT: Lamellar macular hole (LMH) represents a well-defined clinical entity with variable pathophysiologic mechanisms and a controversial therapeutic approach. The purpose of the present work is to present a patient with an epiretinal membrane (ERM)-associated LMH on the background of exudative age-related macular degeneration (AMD) that was successfully managed with pars plana vitrectomy. Interventional case report. A 67-year-old man presented with progressive visual loss OS of 5 months' duration. He was diagnosed with an ERM-associated LMH with coexisting subretinal fluid arising by a neovascular membrane on the background of exudative AMD confirmed with fundus fluorescein angiography. He underwent a 3-port pars plana vitrectomy with ERM-internal limiting membrane peeling and gas tamponade (14% C3F8) for treatment of the LMH and ERM with a view to undergo anti-vascular endothelial growth factor treatment for the exudative AMD. Postoperative optical coherence tomography demonstrated complete closure of the LMH with simultaneous total subretinal fluid absorption that was maintained at the 2-month follow-up period. To our knowledge, this is the first report whereby pars plana vitrectomy in a patient with an ERM-associated LMH on the background of exudative AMD resulted in improvement of both clinical entities. The latter strengthens the role of vitreous traction elimination in exudative AMD and highlights the need for further research.
    European journal of ophthalmology 11/2010; 20(6):1086-8. · 1.07 Impact Factor

Publication Stats

1 Citation
4.24 Total Impact Points


  • 2011
    • Harokopion University of Athens
      Athínai, Attica, Greece