Akinyele O Adisa

Publications of Akinyele O Adisa

• Clinico-pathological profile of head and neck malignancies at University College Hospital, Ibadan, Nigeria.

  Authors: Akinyele O Adisa, Bukola F Adeyemi, Abideen O Oluwasola, Bamidele Kolude, Effiong E U Akang, Jonathan O Lawoyin

  Head & face medicine. 01/2011; 7:9.

  This retrospective study analysed head and neck malignancies seen over a 19-year period at the University College Hospital, Ibadan. One thousand, one hundred and ninety two patients with head andThis retrospective study analysed head and neck malignancies seen over a 19-year period at the University College Hospital, Ibadan. One thousand, one hundred and ninety two patients with head and neck malignancies were analysed according to age, gender, topography and histology. There was an annual hospital frequency of 62 cases per year. The overall mean age for these malignancies was 43.9 (SD ± 19.3) years. The lesions from the respiratory tract were the most frequent (43.2%) of all cases. The palate was the most frequent intra-oral site (13.8%). Epithelial malignancies constituted 73.4% of all cases with a male: female ratio of 2:1, a mean age of 48.1 (SD ± 17.5) years and were mostly located in the larynx (19.7%). Lymphomas constituted 17.5% of all head and neck cancers with a male: female ratio of 1.6:1, a mean age of 35.1 (SD ± 20.6) years and nodal involvement (39.7%) was most common. Sarcomas constituted 8.9% of all malignancies with a male: female ratio of 1.5:1, mean age of 27.1 (SD ± 16.7) years and the maxillofacial bones (42.5%) were most commonly involved. Neuroendocrine malignancies accounted for 0.2% of head and neck malignancies with a male: female ratio of 1:1, a mean age of 28.5 (SD ± 6.4) years and both cases involved the nose. This study has further confirmed that carcinomas remain the most frequent cancers of the head and neck region in south-western Nigeria.

• Immunohistochemical analysis of undifferentiated and poorly-differentiated head and neck malignancies at a tertiary hospital in Nigeria.

  Authors: Akinyele O Adisa, Abideen O Oluwasola, Bukola F Adeyemi, Bamidele Kolude, Effiong Eu Akang, Jonathan O Lawoyin

  Head & neck oncology. 11/2010; 2:33.

  This is a retrospective analysis of poorly-differentiated head and neck malignancies at University College Hospital, Ibadan. Eighty-six poorly-differentiated neoplasms were categorized as carcinomas,This is a retrospective analysis of poorly-differentiated head and neck malignancies at University College Hospital, Ibadan. Eighty-six poorly-differentiated neoplasms were categorized as carcinomas, sarcomas, lymphomas or neuroendocrine cancers with a panel of 7 antibodies (cytokeratin AE1/AE3, vimentin, desmin, myogenin, leukocyte common antigen and neuron-specific enolase). Immunohistochemical and original hematoxylin-eosin diagnoses were contrasted.The male: female ratio was 2.5:1, with mean age of 38.9 years. Nasopharynx, nose and maxillofacial bones were the most common locations. Immunohistochemistry confirmed 54.8% of carcinomas, 70.6% of sarcomas and 80% of lymphomas.Hematoxylin-eosin was able to distinguish between sarcoma and lymphoma but differentiation between a carcinoma and neuroendocrine lesion was poor. Further studies are required to maximize the role of immunohistochemistry as an ancillary diagnostic tool in the West African sub-region.

• Immunohistochemical analysis of undifferentiated and poorly-differentiated head and neck malignancies at a tertiary hospital in Nigeria

  Authors: Akinyele O Adisa, Abideen O Oluwasola, Bukola F Adeyemi, Bamidele Kolude, Effiong EU Akang, Jonathan O Lawoyin

• Congenital epulis.

  Authors: Bukola F Adeyemi, Abideen O Oluwasola, Akinyele O Adisa

  Indian journal of dental research : official publication of Indian Society for Dental Research. 21(2):292-4.

  Congenital epulis of the newborn is a very rare and unique tumor first described in 1871 by Neuman. It has a female predilection. It is a tumor with no tendency to recur after excision. TheCongenital epulis of the newborn is a very rare and unique tumor first described in 1871 by Neuman. It has a female predilection. It is a tumor with no tendency to recur after excision. The histogenesis of the lesion is unknown, but it is believed to be of mesenchymal origin. We report a 2-day-old female with tumor mass on the anterior mandibular alveolar ridge, which demonstrated immunoreactivity for vimentin, S-100 and neuron-specific enolase; thus, suggesting a similar histogenesis with granular cell tumor.