Adnan Sadiq

Maimonides Medical Center, Brooklyn, New York, United States

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Publications (24)86.54 Total impact

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    ABSTRACT: Rare Disease Case Report PostersSESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Amyloid Cardiomyopathy is characterized by bi-ventricular thickening due to amyloid deposition leading to diastolic dysfunction. A 73 year old female with no past medical history presented to our emergency department (ED) with gradually worsening shortness of breath for few weeks. She denied any associated complaints of chest pain, palpitations or dizziness. On physical exam, the patient had bilateral rales at the lung bases. The electrocardiogram showed low voltage complexes with right bundle branch block and left anterior fascicular block. The laboratory work came back significant for an elevated BNP (1450 pg/ml) with a normal complete blood count, serum chemistry and negative cardiac biomarkers. The patient was treated with intravenous diuretics in the ED and admitted to a telemetry floor. The echocardiogram performed on admission revealed concentric bi-ventricular hypertrophy resulting in a restrictive pattern and highly echogenic myocardium with 'sparkling appearance', suggestive of Cardiac Amyloidosis. The LV systolic function was moderately decreased with global hypokinesis and there was bilateral atrial enlargement along with thickening of valve leaflets and inter-atrial septum. A Cardiac MRI also showed delayed nodular enhancement of the myocardium indicative of an infiltrative cardiomyopathy such as Amyloid. Patient underwent an abdominal wall fat pad biopsy which came positive for light-chain Amyloidosis. Amyloid Cardiomyopathy most commonly presents with heart failure, conduction abnormalities or exertional syncope due to inability to augment cardiac output. The combination of increased ventricular mass on echocardiogram and reduced electrocardiographic voltages, along with granular appearance of the myocardium is highly suggestive of Amyloid Cardiomyopathy. The diagnosis can be confirmed by demonstrating amyloid deposits on histologic examination of tissues from abdominal fat pad or kidney in patients with appropriate cardiac findings. Cardiac amyloidosis should be considered in any adult with unexplained heart failure and an echocardiogram showing increased wall thickness with a nondilated left ventricular cavity, particularly when associated with low voltage on electrocardiogram.Reference #1: N/ADISCLOSURE: The following authors have nothing to disclose: Sameer Chadha, On Chen, Sunday Olatunde, Adnan Sadiq, Gerald Hollander, Jacob ShaniNo Product/Research Disclosure Information.
    Chest 03/2014; 145(3 Suppl):558A. · 5.85 Impact Factor
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    ABSTRACT: Left ventricular (LV) pseudo aneurysm is a contained rupture of ventricular wall by adherent pericardium or scar tissue. We present a case of a 70 year-old male presented with exertional dyspnea for 2 months and found to have giant LV pseudo aneurysm on transthoracic echocardiogram, cardiac MRI and angiogram. To our knowledge such a large pseudo aneurysm involving LV apex and presenting as congestive heart failure is the first case in literature.
    Journal of Thrombosis and Thrombolysis 02/2014; · 1.99 Impact Factor
  • Herz 03/2013; · 0.78 Impact Factor
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    ABSTRACT: Tako-tsubo cardiomyopathy was first described in Japan in 1990. The clinical presentation of Tako-tsubo cardiomyopathy (TCM) is similar to an acute myocardial infarction with patients having chest pain, ST segment elevations on EKG and elevated cardiac biomarkers. In TCM, however, the elevation in cardiac enzymes is usually mild. We report a case of TCM where the patient had Troponin I elevation up to 42.3ng/ml. To the best of our knowledge, this is the first case in which such high troponins have been reported in a patient with Tako-tsubo cardiomyopathy.
    Heart Lung &amp Circulation 02/2013; · 1.25 Impact Factor
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    ABSTRACT: Infective endocarditis (IE) is usually caused by Streptococcus, Staphylococcus or Enterococcus species or slow-growing HACEK organisms. We report an extremely rare case of IE caused by Gemella sanguinis.
    The American Journal of the Medical Sciences 01/2013; · 1.33 Impact Factor
  • Arquivos brasileiros de cardiologia 01/2013; 100(1):e14-e15. · 1.32 Impact Factor
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    ABSTRACT: Aneurysms of the sinus of Valsalva are rare congenital lesions. Less often, they are encountered secondary to trauma, infective endocarditis or syphilis. The majority of these aneurysms arise from the right coronary sinus. The present report describes a rare case of an aneurysm arising from the noncoronary sinus of Valsalva and rupturing into the right atrium. Patients with unruptured aneurysms often remain asymptomatic. Rupture of the aneurysm usually causes the appearance of a continuous murmur in the left sternal border. Common sites of rupture include the right ventricle, right atrium or left atrium. Surgical repair is usually associated with a favourable outcome.
    Experimental and clinical cardiology 09/2012; 17(3):148-9. · 1.10 Impact Factor
  • QJM: monthly journal of the Association of Physicians 08/2012; · 2.36 Impact Factor
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    Journal of the American College of Cardiology 05/2012; 59(22):e43. · 14.09 Impact Factor
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    Journal of the American College of Cardiology 05/2012; 59(19):1729. · 14.09 Impact Factor
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    ABSTRACT: Tako-tsubo cardiomyopathy is a relatively recently recognized clinical entity, which presents similar to an acute myocardial infarction but there is no evidence of obstructive coronary artery disease on cardiac catheterization. It mostly affects postmenopausal women and an episode of acute illness or stress can often be identified preceding the presentation. Tako-tsubo cardiomyopathy (TCM) usually has a favorable outcome and an excellent prognosis but, in rare instances, it can be associated with life threatening complications. We report a unique case of TCM where the patient presented with a transient complete heart block.
    Heart & lung: the journal of critical care 03/2012; · 1.04 Impact Factor
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    ABSTRACT: A 27-year-old man was diagnosed with infective endocarditis due to Streptococcus agalactiae. Large vegetations were seen on the anterior mitral valve leaflet and also on the right ventricular side of a membranous ventricular septal defect. Streptococcus agalactiae is a rare cause of endocarditis, and it is very rare to find large vegetations around ventricular septal defect. The authors present this interesting case of unusual endocarditis with vegetations in both the right and left heart. This case is the first reported case of infective endocarditis involving the left and the right sides of the heart at the same time in a nonintravenous drug user.
    The American Journal of the Medical Sciences 01/2012; 343(4):328-9. · 1.33 Impact Factor
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    ABSTRACT: WEBSITE FEATURE.
    Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 01/2012; 39(3):446-7. · 0.67 Impact Factor
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    ABSTRACT: We present a case of a rare complication of atrial septal defect (ASD) device closure causing cor triatriatum dextro iatrogenica. A 29-year-old female presented with sudden onset dysarthria and ataxia and was found to have basilar and thalamic infarcts. Further evaluation using transthoracic echocardiography revealed an ASD which was repaired using the Gore HELEX septal occluder. Transesophageal echocardiography done after 2 months of ASD closure revealed an interesting finding termed cor triatriatum dextro iatrogenica. We briefly describe the case and discuss the relevant literature.
    Echocardiography 11/2011; 29(2):E45-7. · 1.26 Impact Factor
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    ABSTRACT: Bacterial pericarditis is a well-known although rare complication of Staphylococcus aureus infection in modern practice. We present a rare case of Staphylococcus pericarditis caused by an infected trichilemmal cyst present on patient's scalp. Our case emphasizes that all cases of bacterial pericarditis should be thoroughly investigated for a source of infection. Constrictive changes can be seen in the pericardium postinfection, as in our patient, and should be treated aggressively. To our knowledge, a case of an infected cyst causing bacterial pericarditis has never been reported previously in the literature.
    Journal of Infection and Chemotherapy 09/2011; 18(2):251-4. · 1.55 Impact Factor
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    ABSTRACT: Infective endocarditis is significantly more common and causes greater morbidity and mortality in patients receiving hemodialysis than in the general population. Episodes of bacteremia during hemodialysis are primarily the result of frequent vascular access through an arteriovenous fistula, a vascular graft, or an indwelling vascular catheter. This leads to dialysis access infection and secondary bacteremia. We describe 4 cases of patients receiving hemodialysis, with an indwelling intravascular dialysis catheter, who developed right-sided endocarditis with vegetations located exclusively on the superior vena cava and right atrium wall. All patients had persistent bacteremia with Staphylococcus, secondary to an indwelling intravascular hemodialysis catheter, which led to seeding of the right-sided cardiac wall, causing infective endocarditis. The rates of acceptance for hemodialysis are increasing, along with improved survival in this group of patients. This will probably lead to an increase in the incidence of infective endocarditis, with atypical presentations such as superior vena cava and right-sided cardiac wall endocarditis.
    Heart & lung: the journal of critical care 09/2011; 41(3):301-7. · 1.04 Impact Factor
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    Journal of the American College of Cardiology 07/2011; 58(5):e9. · 14.09 Impact Factor
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    ABSTRACT: Hypereosinophilic syndrome is a rare condition characterized by idiopathic eosinophilia with organ system involvement. Cardiac involvement portends a less favorable prognosis as it can be complicated by development of heart failure, valvular dysfunction, and restrictive cardiomyopathy. We present a rare case of hypereosinophilic syndrome with FIP1L1/PDGFRA fusion in a 50-year-old male associated with thrombus in left and right ventricle.
    Echocardiography 07/2010; 27(6):E57-9. · 1.26 Impact Factor
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    ABSTRACT: A young man presented with a new heart murmur. History revealed that the patient was from Ukraine, which was affected by the Chernobyl nuclear plant explosion in 1986. Physical examination revealed murmurs of mitral regurgitation and aortic stenosis. Transesophageal echocardiography revealed severely calcified mitral and calcified tricuspid aortic valves with mitral and aortic regurgitation and aortic stenosis. Following valve replacement surgery, pathologic examination of the valves showed severe dystrophic calcifications and changes suggestive of a chronic inflammatory process such as radiation-induced valve disease. In the absence of another etiology explaining such severe valve disease in a young man, it can only be surmised that heavy radiation exposure from the nuclear plant caused this significant valve damage.
    Journal of the American Society of Echocardiography: official publication of the American Society of Echocardiography 09/2009; 22(8):973.e1-3. · 2.98 Impact Factor
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    ABSTRACT: Intracardiac blood cysts are thin-walled cysts, lined by flattened, cobblestone-shaped epithelium, and filled with nonorganized blood. During autopsy, they are found on cardiac valves in approximately 50% of infants below the age of 2 months and are rarely found after the age of 2 years. We report a rare case of blood cyst attached to the mitral valve and a possible cause of an embolic stroke.
    Echocardiography 08/2009; 26(6):736-8. · 1.26 Impact Factor