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ABSTRACT: We present the clinical scenario of acute abdominal pain in a 27-year-old man with recent-onset type 1 diabetes mellitus. Evaluation of the patient revealed elevated levels of serum amylase, lipase, and transaminase without any biliary obstruction. He had elevated serum IgG4 levels, and his computed tomography scan showed features consistent with autoimmune pancreatitis. Further evaluation revealed celiac disease. He was treated as a patient with autoimmune pancreatitis and was started on steroids in addition to a gluten-free diet. His liver function improved in 6 weeks. He gained weight and his glycemic control also improved. Magnetic resonance cholangiopancreatography after 3 months revealed complete resolution of pancreatic enlargement. The patient is being followed up in our clinic since the past 3 years. To the best of our knowledge and according to the Medline search, this is the first case report of celiac disease as an association of autoimmune pancreatitis.
European Journal of Gastroenterology & Hepatology 11/2011; 23(12):1270–1272. · 1.76 Impact Factor
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ABSTRACT: The use of bee venom as a therapeutic agent for the relief of joint pains dates back to Hippocrates, and references to the treatment can be found in ancient Egyptian and Greek medical writings as well. Also known as apitherapy, the technique is widely used in Eastern Europe, Asia, and South America. The beneficial effects of bee stings can be attributed to mellitinin, an anti-inflammatory agent, known to be hundred times stronger than cortisone. Unfortunately, certain substances in the bee venom trigger allergic reactions which can be life threatening in a sensitized individual. Multiple stings are known to cause hemolysis, kidney injury, hepatotoxicity and myocardial infarction. The toxicity can be immediate or can manifest itself only weeks after the exposure. We describe hepatotoxicity in a 35-year-old female, following bee sting therapy for multiple sclerosis. She presented to our clinic 3 wk after therapy with a history of progressive jaundice. The patient subsequently improved, and has been attending our clinic now for the last 9 mo.
World journal of hepatology. 10/2011; 3(10):268-70.
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ABSTRACT: Bezoar is the accumulation of exogenous undigested materials in the gastrointestinal tract. Various names have been used to describe bezoars based on the accumulated material. Commonly seen types are phytobezoar (composed of vegetable matter and seeds of fruits), tricobezoar (hair) lactobezoar (milk cuds). Lithobezoar (composed of stones and rocks) is uncommon and only limited reports are available in the English literature. The authors report a case of gastrointestinal lithobezoar presenting with ulcer-like abdominal pain. Some of the stones were removed endoscopically and some got expelled out after the use of promotility drugs. Invariably, there are predisposing factors for such behaviour. This case emphasises a meticulous psychiatric evaluation in a given patient, in order to prevent recurrence of symptoms.
Case Reports 01/2011; 2011.
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ABSTRACT: We describe the clinical scenario of a young male with history of non ulcer dyspepsia who had endoscopic evidence of gastric polyposis in antral area. The polyps disappeared four months after proton pump inhibitors were stopped. Proton pump inhibitors have been linked to gastric fundal polyposis and not antral gland polyposis. This is the first report originating from an Asian country describing antral gland polyposis (AGPs) in a patient on long-term PPI therapy with no evidence of Helicobacter pylori. A case report with brief review is presented.
German medical science : GMS e-journal 01/2010; 8.