A.B.J. Prakken

Publications (134)4.06 Total impact

• Article: Auto-immuunziekten van het houdings- en bewegingsapparaat: juveniele idiopathische artritis

  J. van der Net, A. B. J. Prakken, W. Kuis, P. J. M. Helders
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  ABSTRACT: Juveniele idiopathische artritis (jia) is een systemische auto-immuunziekte die vooral de gewrichten treft. De gevolgen van de ziekte zijn veelzijdig en liggen op het gebied van de groei en psychosociale en motorische ontwikkeling. In dit reviewartikel worden de nieuwe ontwikkelingen op het gebied van classificatie, etiologie, pathofysiologie, prognose en behandeling van jia besproken. Juvenile idiopathic arthritis (jia) is a systemic autoimmune disease affecting primarily the joints. The disease has many consequences especially on growth, psychosocial and physical development. This review article discusses new developments in classification, aetiology, pathophysiology, prognosis and treatment of jia.
  Tijdschrift voor kindergeneeskunde 04/2012; 71(1):249-253.
• Article: The physiological and physical determinants of functional ability measures in children with juvenile dermatomyositis.

  T Takken, E Elst, N Spermon, P J M Helders, A B J Prakken, J van der Net
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  ABSTRACT: To study the relationships of muscle strength and maximal oxygen consumption (VO(2peak)) with Childhood Health Assessment Questionnaire (CHAQ) score, Childhood Myositis Assessment Score (CMAS) and Child Health Questionnaire [physical summary (CHQ-PhS) and psychosocial summary (CHQ-PsS)] scores in juvenile dermatomyositis. Fifteen patients (age 5-14 yr) participated. CMAS, CHAQ, CHQ, muscle strength and VO(2peak) were measured. Correlations revealed significant relationships between CHAQ and (i) muscle strength (r=-0.72) and (ii) absolute VO(2peak) (r=-0.68); between CMAS and relative VO(2peak) (r=0.73); and between CHQ-PhS and (i) muscle strength (r=0.57) and (ii) relative VO(2peak) (r=0.58). Backward regression analysis showed that muscle strength was the best indicator of variation in CHAQ. Age and relative VO(2peak) were the best indicators for CMAS. Body mass and age were the best indicators for CHQ-PsS. Body mass and muscle strength were the best indicators for CHQ-PhS. CMAS, CHAQ and CHQ correlate with muscle strength and VO(2peak). CMAS, CHAQ and CHQ depend on different physical and physiological variables.
  Rheumatology 05/2003; 42(4):591-5. · 4.06 Impact Factor
• Article: Nieuwe therapie opties: immunotherapie voor Juveniele Idiopathische Artritis met PanDR bindende HSP60 peptides

  A.B.J. Prakken, S.S.M. Kamphuis, M Boerhof, G Gordon, M Haverkamp, W. van Eden, G.T. Rijkers, W. Kuis, S. Albani
• Article: Monocytes and loss of HLA-dr expression following cardiac surgery in children

  A.W.L. Schadenberg, S.J. Vastert, F.C.M. Evens, W. Kuis, A.J. van Vught, A.B.J. Prakken, N.J.G. Jansen
• Article: Identification of Pan-DR binding T-cell epitopes of human and mycobacterial hsp60 in patients with Juvenile Idiopathic Arthritis

  A.B.J. Prakken, S.S.M. Kamphuis, G Gordon, I.M. de Kleer, A Martini, M Massa, W. van Eden, W. Kuis, S. Albani
• Article: Toename van gemelde HIV-1-infectie bij kinderen in Nederland, 1982-1997: meer verticale transmissie en groter aandeel van allochtone kinderen

  I.M. de Kleer, C.S.P.M. Uiterwaal, N. Nauta, R A Hirasing, A.B.J. Prakken, E R de Graeff-Meeder
• Article: Artificial antigen presenting cells as a tool for antigen specific T cell detection and isolation

  R. Vita, P Lanza, R Billetta, M. Klein, A.B.J. Prakken, S. Albani
• Article: Identification of joint inflammation-specific T cell responses in juvenile idiopathic arthritis: Potential targets for immunotherapy.

  S.S.M. Kamphuis, J.H.M. van Bilsen, M Haverkamp, G Gordon, W. Kuis, M.H.M. Wauben, A.B.J. Prakken
• Article: Arthritis protective regulatory potential of self-hsp cross-reactive T cells.

  W. van Eden, U Wendling, A.G.A. Paul, A.B.J. Prakken, P. van Kooten, R van der Zee
• Article: Op weg naar immunotherapie voor Juveniele Idiopathische Arthritis en Rheumatoide Arthritis:identificatie van pan-DR bindende T cel epitopen van heat shock protein 60

  A.B.J. Prakken, S.S.M. Kamphuis, M Boerhof, G Gordon, W. van Eden, G.T. Rijkers, W. Kuis, S. Albani
• Article: 18 Children after autologous stem cell transplantation for refractory juvenile idiopathic arthritis: 1 to 51 months of follow-up

  I.M. de Kleer, D. Brinkman, G.T. Rijkers, A.B.J. Prakken, R. ten Cate, W. Kuis, N.M. Wulffraat
• Article: Immunopotentiating heat shock proteins: negotiators between innate danger and control of autoimmunity

  W. van Eden, A.P. Koets, P. van Kooten, A.B.J. Prakken, R van der Zee
• Article: 15th Paediatric Rheumatology European Society Congress

  S.J. Vastert, J.F. Swart, A.B.J. Prakken
• Article: Mycobacterial Hsp70 immunization inhibits proteoglycan-induced arthritis

  S.E. Berlo, P. van Kooten, C.B.M. ten Brink, R van der Zee, M Singh, A.B.J. Prakken, T Glant, W. van Eden, C.P.M. Broeren
• Article: Current perspectives of autologous stem cell transplantation for severe juvenile idiopathic arthritis

  N.M. Wulffraat, EM Rooijen, R Tewarie, D. Brinkman, A.B.J. Prakken, W. Kuis
• Article: Meningococcal c vaccination does not aggravate juvenile idipathic arthritis and induces specific antibody titers

  A. Ronaghy, E. Huijssoon, M. van Rossum, G.T. Rijkers, E.A.M. Sanders, P.E. Vermeer-de Bondt, A.W. Hoes, J. van der Net, W. Kuis, M J D van Tol, C.W.A.M. Engels - Humblet, A.B.J. Prakken, N.M. Wulffraat
• Article: Vaccination does not exacerbate juvenile idiopathic arthritis disease activity in a cohort of Dutch patients.

  A. Ronaghy, E. Huijssoon, M. van Rossum, A.B.J. Prakken, G.T. Rijkers, P.E. Vermeer-de Bondt, M J D van Tol, A.W. Hoes, J. van der Net, W. Kuis, C.M.A. Rademaker, N.M. Wulffraat
• Article: Stress proteins as inducers and targets of regulatory T Cells in arthritis

  W. van Eden, F. Hauet-Broere, S.E. Berlo, L Paul, R van der Zee, I.M. de Kleer, A.B.J. Prakken, L.S. Taams
• Article: Hsp70 and cardiac surgery: molecular chaperone and inflammatory regulator with compartmentalized effects.

  P.R. de Jong, A.W.L. Schadenberg, N.J.G. Jansen, A.B.J. Prakken
• Article: Recognition of multiple HSP60 epitopes in patients with juvenile idiopathic arthritis opens the way for antigen-specific immunotherapy

  S.S.M. Kamphuis, W. de Jager, I.M. de Kleer, G Gordon, E Koffeman, M Massa, A Martini, G.T. Rijkers, W. van Eden, W. Kuis, A.B.J. Prakken, S. Albani