Alp Erdin Koyuturk

Izmir Katip Celebi Universitesi, Temnos, İzmir, Turkey

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Publications (5)4.35 Total impact

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    ABSTRACT: The aims of this study were to evaluate the effect of an antibacterial monomer-containing self-etching adhesive in reducing enamel demineralization around orthodontic brackets in vivo and to compare it with the conventional adhesive system quantitatively. Fourteen orthodontic patients were randomly divided into 2 equal groups; they received brackets fitted to all their teeth, bonded with either Clearfil Protect Bond (Kuraray Medical, Okayama, Japan) (experimental group) or Transbond XT (3M Unitek, Monrovia, Calif) (control group). Block randomization to obtain equal numbers in each group was used. After 30 days, all first premolars were extracted with orthodontic indications and longitudinally sectioned. Demineralization was assessed by cross-sectional microhardness. Determinations were made at the bracket edge cementing limits and at occlusal and cervical points 100 and 200 μm away from the edge. In all of these positions, 6 indentations were made at depths of 10 to 90 μm from the enamel surface. Analysis of variance (ANOVA) and the Tukey post-hoc test were used. The statistical significance level was set at P <0.05. ANOVA showed statistically significant differences for adhesive type, position, depth, and their interactions (P <0.05). The multiple comparison test showed that the antibacterial monomer-containing adhesive was significantly more efficient than the conventional adhesive system, reducing enamel demineralization in almost all evaluations (P <0.05). The results indicated that using antibacterial monomer-containing adhesive for bonding orthodontic brackets successfully inhibited caries in vivo. This cariostatic effect was localized at the area around the brackets and was significant after 30 days.
    American journal of orthodontics and dentofacial orthopedics: official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 05/2011; 139(5):650-6. · 1.33 Impact Factor
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    T Uysal, M Amasyali, A E Koyuturk, S Ozcan
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    ABSTRACT: The aim of this study was to evaluate the in vivo and in vitro effects of a casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride containing topical agents in reducing enamel demineralization around orthodontic brackets, and to compare this with a control group. Twenty-one patients and 60 extracted premolars were divided into three groups: two experimental and one control. Tooth Mousse® (CPP-ACP gel; GC-Corp, Tokyo, Japan) and Fluoridin N5® (Fluoride gel; Voco-GmbH, Cuxhaven, Germany) were applied to tooth surfaces around orthodontic brackets in the experimental groups. Teeth were extracted after 60 days to evaluate the in vivo effects of the testing materials. For the in vitro experiment, samples were cycled for 14 days through a daily procedure of demineralization. All teeth were sectioned and evaluated by superficial microhardness analysis. An indentation was made from two positions (occlusal-cervical) and one depth (10 μm). Comparisons of occlusal and cervical microhardness scores for all specimens showed no statistically significant side differences. A multiple comparison test showed that the use of CPP-ACP and fluoride containing topical gels were more significantly efficient than the control group (p<0.001). No significant differences were detected between CPP-ACP and the fluoride groups against demineralization. In vivo and in vitro evaluations indicated that CPP-ACP and fluoride containing agents successfully inhibited caries around orthodontic brackets.
    Australian Dental Journal 09/2010; 55(3):268-74. · 1.37 Impact Factor
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    ABSTRACT: The aim of this study was to evaluate the in vivo effects of an amorphous calcium phosphate-containing orthodontic composite in reducing enamel demineralization around orthodontic brackets, and to compare it with the control. Fourteen orthodontic patients were divided into two equal groups. They received brackets fitted to all first premolars, bonded with either Aegis Ortho® (The Bosworth Co.), an ACP-containing orthodontic composite (experimental group), or Concise® (3M Dental Products), a resin-based orthodontic composite (control group). After 30 days, the teeth were extracted and longitudinally sectioned, and evaluated by superficial-microhardness analysis. The determinations were made at the bracket edge cementing limits and at occlusal and cervical points 100 and 200 μm away from the edge. In all of these positions, indentations were made at depths of 10, 20, 30, 50, 70, and 90 μm from the enamel surface. Analysis of variance (ANOVA) and Tukey post hoc test was used. The statistical significance level was set at p<0.05. The ANOVA showed statistically significant differences for position, material, depth, and their interactions (p<0.001). The multiple comparison test showed that the ACP-containing orthodontic composite was significantly more efficient than the control composite, reducing enamel demineralization in almost all evaluations (p<0.001). Present results indicated that ACP-containing orthodontic composite for bonding orthodontic brackets successfully inhibited demineralization in vivo. This effect was localized to the area around the brackets and was statistically significant after 30 days.
    Australian Dental Journal 09/2010; 55(3):285-91. · 1.37 Impact Factor
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    ABSTRACT: A preliminary study using laser fluorescence suggested that amorphous phosphate-containing orthodontic composites may prevent demineralisation around bonded orthodontic brackets. To compare the microhardness of the enamel around brackets bonded with an amorphous calcium phosphate-containing orthodontic composite (ACP-containing) with the microhardness of the enamel around brackets bonded with a conventional composite resin. Forty extracted upper premolars were used. Orthodontic brackets were bonded to the teeth with either an ACP-containing composite resin (N = 20) or a conventional composite resin (N = 20). The latter were used as the control. The crowns of all teeth were painted with an acid resistant varnish, leaving a 2 mm ring of exposed enamel around the brackets. The teeth were then subjected to a daily cycle of demineralisation for 6 hours and remineralisation for 18 hours for 21 days. Each tooth was sectioned and the microhardness of the enamel determined 25, 50, 75, 100 and 150 microm from the surface. The enamel was significantly harder 25 microm (p = 0.000) and 50 microm (p = 0.001) from the enamel surface in the teeth with brackets bonded with the ACP-containing composite resin as compared with the control teeth. ACP-containing orthodontic composite resins may reduce the enamel decalcification found in patients with poor oral hygiene.
    Australian orthodontic journal 05/2010; 26(1):10-5. · 0.28 Impact Factor
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    Tancan Uysal, Mihri Amasyali, Alp Erdin Koyuturk, Deniz Sagdic
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    ABSTRACT: The aim of this in vitro study was to compare the efficacy of Amorphous Calcium Phosphate (ACP)-containing orthodontic composite and resin-modified glass ionomer cement (RMGIC) on enamel demineralization adjacent to orthodontic brackets evaluated by a new laser fluorescence device. Sixty extracted maxillary premolars were used in the present study. Twenty orthodontic brackets were bonded with ACP-containing orthodontic adhesive (Aegis-Ortho), 20 were bonded with RMGIC (Fuji Ortho LC) and 20 were bonded with Transbond XT composite as the control. All samples were then cycled for 21 days through a daily procedure of demineralization for 6 hours and remineralization for 17 hours. After this procedure, demineralization evaluations were undertaken by a pen-type laser fluorescence device (DIAGNO-dent Pen). Analysis of variance (ANOVA) and Tukey test was used for statistical evaluation, at P<.05 level. According to ANOVA, significant demineralization variations (DeltaD) were determined among groups (F=6.650; P<.01). The ACP-containing composite showed the lowest (mean: 8.98+/-2.38) and the control composite showed the highest (mean:12.15+/-3.83) DeltaD, during 21 days demineralization process (P<.01). Significant difference was also observed between the DeltaD scores of the RMGIC (mean: 9.24+/-2.73) and control (P<.05). No significant differences was found in preventive effects of ACP-containing composite and RMGIC (P<.05) against demineralization. The use of both ACP-containing orthodontic composite and RMGIC should be recommended for any at-risk orthodontic patient to provide preventive actions and potentially remineralize subclinical enamel demineralization.
    European journal of dentistry 04/2009; 3(2):127-34.