M Sanjaume

Publications (3)5.51 Total impact

• Article: [Post-hospital mortality in patients re-admitted due to COPD. Utility of BODE index].

  M Sanjaume, P Almagro, M Rodríguez-Carballeira, B Barreiro, J L Heredia, J Garau
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  ABSTRACT: The BODE index can accurately predict mortality in ambulatory patients with COPD, although its utility in hospitalized patients is unknown. We prospectively evaluated all patients hospitalized during one year for acute exacerbation of COPD with one or more admissions in the previous year. On discharge, previous functional dependence, comorbidity, depression and quality of life, among other variables, were evaluated. Body mass index, 6-minute walking test, dyspnea scale and spirometry with a post-bronchodilator test were performed on the last day of hospitalization and the BODE index was calculated using these data. A total of 66 patients were included, with a mean age of 71.6 +/- 8.9 years. Of these patients, 42 (63.6%) died before the end of the study (median follow-up 1,490 days). A higher mortality was observed among the oldest patients (p < 0.004), those with more comorbidities (p < 0.05), worse score on the BODE index (p < 0.006; OR 1.3; CI 95%: 1.07-1.54) and the dyspnea scale (p < 0.008). Functional dependence (p < 0.02), and pCO2 > 45 mmHg at discharge (p < 0.001) were also significant predictors of mortality. In the multivariate analysis, only hypercapnia (p < 0.004; OR 3.48; CI 95% 1.49-8.14) and the BODE index (p < 0.0005; OR 1.47; CI 95%: 1.18-1.82) were independent predictors of mortality. The BODE index measured at hospital discharge is an accurate and reliable predictor of mortality in patients who require several admissions for acute exacerbations of COPD.
  Revista Clínica Española 09/2009; 209(8):364-70. · 2.01 Impact Factor
• Article: [Mammary, cutaneous and nodal tuberculosis without pulmonary affectation in patient without apparent immunosuppression].

  E Carrillo Casas, M Rodríguez Carballeira, M Sanjaume, J Martínez Lacasa, P Vives, J Garau
  Revista Clínica Española 07/2003; 203(6):312-3. · 2.01 Impact Factor
• Article: [Cerebral SPECT with thallium-201 in the differential diagnosis of focal cerebral lesions in patients with AIDS].

  M Sanjaume, M Rodríguez-Carballeira, E Mauri, J Martínez-Lacasa, J R García, J Garau
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  ABSTRACT: The aim of this study was to analyze the usefulness of cerebral SPECT with thallium-201 in patients with the acquired human immunodeficiency syndrome (AIDS) and focal cerebral lesions. Six patients with AIDS and focal cerebral lesions in whom a cerebral SPECT was performed with thallium-201 are described. Treatment was initiated with antiToxoplasma drugs in all patients. The clinical response, serology for positive toxoplasma and radiologic improvement were criteria for the diagnosis of encephalitis by Toxoplasma. In the remaining cases, cerebral biopsy and/or necropsy study were carried out. In the 2 patients in whom cerebral SPECT demonstrated enhancement of the lesion, the pathologic diagnosis was cerebral lymphoma. Of the 4 remaining cases in whom no enhancement was observed, three corresponded to cerebral toxoplasmosis and one to progressive multifocal leucoencephalopathy. Cerebral SPECT with thallium-201 is a simple, specific and useful technique for the differentiation of primary cerebral lymphoma from the remaining inflammatory cerebral lesions which may be present in AIDS patients.
  Enfermedades Infecciosas y Microbiología Clínica 02/1997; 15(1):28-31. · 1.49 Impact Factor