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ABSTRACT: Synaptogyrins are conserved components of the exocytic apparatus and function as regulators of Ca(2+)-dependent exocytosis. The synaptogyrin family comprises three isoforms: two neuronal (synaptogyrin-1 and -3) and one ubiquitous (synaptogyrin-2) form. Although the expression patterns of the exocytic proteins synaptotagmin-1, SNAP-25, synaptobrevin-2 and synaptophysin have been elucidated in taste buds, the function and expression pattern of synaptogyrin-1 in rat gustatory tissues have not been determined. Therefore, we examined the expression patterns of synaptogyrin-1 and several cell-specific markers of type II and III cells in rat gustatory tissues. Reverse transcription/polymerase chain reaction assays and immunoblot analysis revealed the expression of synaptogyrin-1 mRNA and its protein in circumvallate papillae. In fungiform, foliate and circumvallate papillae, the antibody against synaptogyrin-1 immunolabeled a subset of taste bud cells and intra- and subgemmal nerve processes. Double-labeling experiments revealed the expression of synaptogyrin-1 in most taste cells immunoreactive for aromatic L-amino acid decarboxylase and the neural cell adhesion molecule. A subset of synaptogyrin-1-immunoreactive taste cells also expressed phospholipase Cβ2, gustducin, or sweet taste receptor (T1R2). In addition, most synaptogyrin-1-immunoreactive taste cells expressed synaptobrevin-2. These results suggest that synaptogyrin-1 plays a regulatory role in transmission at the synapses of type III cells and is involved in exocytic function with synaptobrevin-2 in a subset of type II cells in rat taste buds.
Cell and Tissue Research 05/2013; · 3.11 Impact Factor
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Shinji Kito,
Hirofumi Koga,
Masaaki Kodama,
Manabu Habu,
Shinya Kokuryo,
Noriaki Yamamoto,
Masafumi Oda,
Takanobu Nishino,
Min Zhang,
Kou Matsuo, [......],
Daigo Yoshiga,
Takeshi Kaneuji,
Shinnosuke Nogami,
Izumi Yoshioka,
Yoshihiro Yamashita,
Tasturou Tanaka,
Ikuya Miyamoto,
Chiaki Kitamura,
Kazuhiro Tominaga,
Yasuhiro Morimoto
Dentomaxillofacial Radiology 04/2013; · 1.08 Impact Factor
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Shinji Kito,
Hirofumi Koga,
Masaaki Kodama,
Noriaki Yamamoto,
Shinya Kokuryo,
Manabu Habu,
Kou Matsuo,
Takanobu Nishino,
Kohzoh Kubota,
Kosuke Muraoka, [......],
Shinobu Matsumoto-Takeda, Yuji Seta,
Tatsurou Tanaka,
Ikuya Miyamoto,
Yoshihiro Yamashita,
Chiaki Kitamura,
Keisuke Nakashima,
Tetsu Takahashi,
Kazuhiro Tominaga,
Yasuhiro Morimoto
[show abstract]
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ABSTRACT: OBJECTIVES: To elucidate whether fluorine-18-labeled ((18)F) fluoro-2-deoxy-d-glucose (FDG) accumulation can reflect the extent of periodontal inflammation, periapical inflammation, or dental caries. STUDY DESIGN: (18)F-FDG accumulations on positron emission tomography (PET)-computed tomography (CT) were retrospectively compared with the size of the bone resorption areas caused by periodontal inflammation, periapical inflammation, or dental caries on panoramic radiographs, CT, and magnetic resonance imaging (MRI) in 44 subjects. RESULTS: A significant correlation was found between the size of the bone resorption area caused by periodontal (r = 0.595, P < .01) or periapical (r = 0.560, P < .01) inflammation and the highest standardized uptake value (SUVmax) of (18)F-FDG accumulation. A significant correlation was found between the periodontal (r = 0.622, P < .01) or periapical (r = 0.394, P < .01) inflammatory findings on MRI and the SUVmax of (18)F-FDG accumulation. The SUVmax of (18)F-FDG around most teeth with caries was under 1.5. CONCLUSIONS: (18)F-FDG accumulation reflects the extent of dental inflammation, not dental caries.
Oral surgery, oral medicine, oral pathology and oral radiology. 09/2012;
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Izumi Yoshioka,
Tatsurou Tanaka,
Manabu Habu,
Masafumi Oda,
Masaaki Kodama,
Shinya Kokuryo,
Shinji Kito,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda, Yuji Seta,
Yuki Fukudome,
Kazuhiro Tominaga,
Sumio Sakoda,
Yasuhiro Morimoto
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ABSTRACT: PURPOSE: The purpose of this study is to elucidate the criteria and limitations for selecting a sagittal split ramus osteotomy (SSRO) alone for patients with skeletal mandibular prognathism and open bite. STUDY DESIGN: The relationship between the mandibular relapse after 1 year and the extent of vertical movement following SSRO alone was investigated for patients with skeletal mandibular prognathism and open bite and the criteria were determined. RESULTS: The limitation in SSRO alone was found to be 3-mm vertical movement at the gonion. There was a significant difference in the mandibular relapse between the patients with >3-mm change and <3-mm change. CONCLUSIONS: For patients with skeletal mandibular prognathism and open bite, if the vertical movement at the gonion is <3 mm, SSRO alone could be an effective treatment. However, if the movement is >3 mm, SSRO alone should be avoided and bimaxillary osteotomies may be a preferable treatment.
Oral surgery, oral medicine, oral pathology and oral radiology. 09/2012;
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Shunji Shiiba,
Tatsurou Tanaka,
Eiji Sakamoto,
Masafumi Oda,
Shinji Kito,
Kentaro Ono,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda, Yuji Seta,
Yoshiki Imamura,
Osamu Nakanishi,
Kiyotoshi Inenaga,
Yasuhiro Morimoto
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ABSTRACT: OBJECTIVES: Whether NVC volume on magnetic resonance (MR) cisternography might be related to the success of local anesthetic block by tetracaine (TNB) as an additional treatment after carbamazepine (CBZ) treatments in patients with trigeminal neuralgia (TN) was evaluated. STUDY DESIGN: Detectable NVC volumes were measured from MR cisternography in 65 patients with TN treated by TNB after CBZ treatments. The correlation between the success of TNB and the NVC volume or the improvement in pain by CBZ was evaluated retrospectively. RESULTS: A significant difference was found between the improvement in pain by CBZ and the success of TNB, but not between NVC volume on MR cisternography and the success of TNB. CONCLUSIONS: The present results suggest that the success of CBZ as initial treatment, but not NVC volume on MR cisternography, may be a significant predictor of the success of TNB as additional therapy in patients with TN.
Oral surgery, oral medicine, oral pathology and oral radiology. 08/2012;
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Masafumi Oda,
Tatsurou Tanaka,
Shinji Kito,
Shinobu Matsumoto-Takeda,
Kozue Otsuka,
Yuki Hayashi,
Nao Wakasugi-Sato,
Izumi Yoshioka,
Manabu Habu,
Shinya Kokuryo, [......],
Noriaki Yamamoto,
Ayataka Ishikawa,
Min Zhang,
Kou Matsuo,
Shunji Shiiba, Yuji Seta,
Yoshihiro Yamashita,
Tetsu Takahashi,
Kazuhiro Tominaga,
Yasuhiro Morimoto
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ABSTRACT: To evaluate fresh blood imaging (FBI), a magnetic resonance imaging technique that does not use contrast, for identifying hemangiomas and feeding arteries in the oral and maxillofacial regions.
For 16 patients with hemangiomas, FBI visualizations of hemangiomas and feeding arteries in the oral and maxillofacial regions were compared with those from 3-dimensional (3D) phase-contrast magnetic resonance angiography (PC-MRA). Comparisons were based on the conspicuities of blood vessels and the 3D relationships of hemangiomas with the surrounding blood vessels.
The conspicuity of hemangiomas, feeding arteries, and blood vessels were significantly better with FBI than with PC-MRA. After differentiating arteries from veins, 3D visualizations of hemangiomas and arteries or veins could be performed with FBI.
FBI is a useful method in oral and maxillofacial regions for identifying the relationships between hemangiomas and the surrounding arteries or veins.
Oral surgery, oral medicine, oral pathology and oral radiology. 04/2012; 113(4):559-66.
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Masafumi Oda,
Tatsurou Tanaka,
Shinji Kito,
Manabu Habu,
Masaaki Kodama,
Shinya Kokuryo,
Ikuya Miyamoto,
Daigo Yoshiga,
Kensuke Yamauchi,
Shinnosuke Nogami, [......],
Ayataka Ishikawa,
Ikuko Nishida,
Katsura Saeki,
Kazumasa Morikawa,
Kou Matsuo, Yuji Seta,
Yoshihiro Yamashita,
Kenshi Maki,
Kazuhiro Tominaga,
Yasuhiro Morimoto
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ABSTRACT: The present paper provides general dentists with an introduction to the clinical applications and significance of magnetic resonance angiography (MRA) in the oral and maxillofacial regions. Specifically, the method and characteristics of MRA are first explained using the relevant MR sequences. Next, clinical applications to the oral and maxillofacial regions, such as identification of hemangiomas and surrounding vessels by MRA, are discussed. Moreover, the clinical significance of MRA for other regions is presented to elucidate future clinical applications of MRA in the oral and maxillofacial regions.
International Journal of Dentistry 01/2012; 2012:865369.
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Tatsurou Tanaka,
Yasuhiro Morimoto,
Shinji Kito,
Ayataka Ishikawa,
Shinya Kokuryo,
Noriaki Yamamoto,
Manabu Habu,
Ikuya Miyamoto,
Masaaki Kodama,
Shinobu Matsumoto-Takeda,
Masafumi Oda,
Nao Wakasugi-Sato,
Kozue Otsuka,
Shunji Shiiba, Yuji Seta,
Yoshihiro Yamashita,
Izumi Yoshioka,
Kou Matsuo,
Tetsu Takahashi,
Kazuhiro Tominaga
11/2011; , ISBN: 978-953-307-723-9
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ABSTRACT: To examine the relationship between the anatomical position and the bone quality of the inferior alveolar nerve (IFAN) canal and long-term neurosensory disturbance (NSD) of the IFAN after a sagittal split ramus osteotomy (SSRO).
CT images were taken of patients with mandibular prognathism. The location of the IFAN and the bone density around the IFAN were measured on CT images. Whether NSD at 6 months and 1 year after SSRO was related to the position and bone quality of the IFAN canal was analyzed.
Significant correlations were found between the anatomical position and the bone quality of the IFAN canal and the period to the resolution of NSD of the IFAN from 3 months to 1 year after SSRO. If the HU values around the IFAN were greater than 300 HU and/or the distance from the buccal aspect of the IFAN canal to the outer buccal cortical margin was less than 6 mm, NSD of the IFAN at 1 year after SSRO was significantly increased.
It is important to pay particular attention to the anatomical position of the IFAN and the bone quality around the IFAN to predict long-term NSD of the IFAN after SSRO.
Journal of cranio-maxillo-facial surgery: official publication of the European Association for Cranio-Maxillo-Facial Surgery 10/2011; 40(6):e178-83. · 1.25 Impact Factor
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Tatsurou Tanaka,
Masafumi Oda,
Shinji Kito,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda,
Kozue Otsuka,
Izumi Yoshioka,
Manabu Habu,
Shinya Kokuryo,
Masaaki Kodama, [......],
Ikuya Miyamoto,
Noriaki Yamamoto,
Ayataka Ishikawa,
Kou Matsuo,
Shunji Shiiba, Yuji Seta,
Yoshihiro Yamashita,
Tetsu Takahashi,
Kazuhiro Tominaga,
Yasuhiro Morimoto
[show abstract]
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ABSTRACT: The aim of this study was to evaluate the 3-dimensional images of thinner main peripheral vessels in oral and maxillofacial regions made without contrast medium by using a new technique, fresh blood imaging (FBI). A second objective was to discern arteries from veins by using the combination of FBI with the subtraction technique.
Images from FBI were compared with those from 3-dimensional phase-contrast magnetic resonance angiography (MRA) of blood vessels in 20 healthy subjects. All images were scored for visualization and image quality of the main blood vessels. In addition, appropriate flow-spoiled gradient pulses were applied to differentiate arteries from veins in the peripheral vasculature using a combination of FBI sequences and subtraction between systole- and diastole-triggered images.
The scores of MRA using FBI for the visualization of thin blood vessels were significantly better than those using phase contrast, whereas scores for the visualization of main blood vessels were equal. Additionally, we succeeded in our initial attempt to differentiate arteries from veins with a reasonable acquisition time.
Our initial experience shows that FBI could be a useful method to identify 3-dimensional vasculature and to differentiate arteries from veins among thinner peripheral vessels in the oral and maxillofacial regions without using contrast medium.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 08/2011; 112(4):493-501. · 1.50 Impact Factor
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ABSTRACT: Taste receptors and their downstream signaling molecules are activated by sugars and sweeteners in the gut and participate in the regulation of glucose transport into enterocytes. The glucose transporter families GLUT and SGLT are responsible for the absorption of glucose, GLUT4 and SGLT1 being expressed preferentially in T1R3-positive taste cells. However, the expression patterns of the other glucose transporters in mouse gustatory tissues have not yet been elucidated. Therefore, we have examined the expression patterns of the glucose transporters (GLUT1-4 and SGLT1-3) in mouse gustatory tissues. Reverse transcription/polymerase chain reaction assays have revealed that GLUT1, 3, and 4 and SGLT1 mRNAs are expressed in the circumvallate papillae. Immunohistochemical analysis has shown that SGLT1 is expressed in a subset of the epithelial cells: from the basal cell layer to the prickle cell layer and in intragemmal and extragemmal epithelium cells in the circumvallate, foliate, and fungiform papillae. GLUT1, GLUT3, and GLUT4 are expressed in the prickle cell layers and/or basal cell layers in these papillae. Moreover, GLUT1, but not GLUT3 or GLUT4, is expressed in a subset of intragemmal and extragemmal epithelium cells in these papillae. Double-labeling experiments have demonstrated that GLUT1-positive taste bud cells coexpress gustducin and inositol 1,4,5-triphosphate receptor type III. These results suggest that SGLT1 and GLUT1 play a role in glucose-sensing and/or transport in mouse taste buds.
Cell and Tissue Research 08/2011; 345(2):243-52. · 3.11 Impact Factor
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Shinobu Matsumoto-Takeda,
Noriaki Yamamoto,
Ikuko Nishida,
Katsura Saeki,
Masafumi Oda,
Kensuke Yamauchi,
Ikuya Miyamoto,
Tatsurou Tanaka,
Shinji Kito,
Nao Wakasugi-Sato, Yuji Seta,
Shunji Shiiba,
Yoshihiro Matsumoto,
Yoshihiro Yamashita,
Kenshi Maki,
Tetsu Takahashi,
Yasuhiro Morimoto
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ABSTRACT: In the present case of a 9-year-old girl with prominent swelling in the mental and facial regions after trauma, repeated magnetic resonance (MR) examinations were performed to evaluate areas of incision, because the swelling became worse and more prominent despite intravenous antibiotic treatment. However, there was no evidence of respiratory tract impingement or deformation, including obliteration, on MR imaging. Therefore, surgical treatment involving an incision because of facial region swelling was cancelled, and the intravenous antibiotic therapy was continued. To prevent misdiagnosis and over-treatment of young children with inflammation of the oral and maxillofacial regions, dentists, including pediatric dentists, should be aware of the clinical usefulness of MR examinations. In particular, MR examinations are non-invasive for young children, because there is no X-ray exposure, and they can be used repetitively. At the same time, the present case demonstrated that it is very difficult to understand and predict changes in the inflammation process associated with children's facial trauma.
Dental Traumatology 04/2011; 27(4):300-4. · 1.20 Impact Factor
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ABSTRACT: Mash1 is expressed in subsets of neuronal precursors in both the central nervous system and the peripheral nervous system. However, involvement of Mash1 in taste cell differentiation has not previously been demonstrated. In this study, we investigated the role of Mash1 in regulating taste bud differentiation using Mash1 KO mice to begin to understand the mechanisms that regulate taste bud cell differentiation. We found that aromatic L-amino acid decarboxylase (AADC) cells were not evident in either the circumvallate papilla epithelia or in taste buds in the soft palates of Mash1 KO mice. However gustducin was expressed in taste buds in the soft palates of Mash1 KO mice. These results suggest that Mash1 plays an important role in regulating the expression of AADC in type III cells in taste buds, which supports the hypothesis that different taste bud cell types have progenitor cells that are specific to each cell type.
Developmental Dynamics 02/2011; 240(4):775-84. · 2.54 Impact Factor
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Izumi Yoshioka,
Tatsurou Tanaka,
Amit Khanal,
Manabu Habu,
Shinji Kito,
Masaaki Kodama,
Masafumi Oda,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda,
Yasuhiro Fukai,
Takatoshi Tokitsu,
Megumi Tomikawa, Yuji Seta,
Kazuhiro Tominaga,
Yasuhiro Morimoto
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ABSTRACT: To elucidate the relationship between the anatomic position of the inferior alveolar nerve (IAN) at the mandibular second molar and the occurrence of neurosensory disturbances of the IAN after sagittal split ramus osteotomy (SSRO) in patients with mandibular prognathism. Also, the present study evaluated the difference in anatomic position of the IAN between patients with and without mandibular prognathism.
Computed tomography images were taken of 28 patients with mandibular prognathism and 30 without prognathism. On these scans, the IANs from the mandibular second molar region to the mandibular foramen in the mandibular ramus were identified. The present study was designed as a cross-sectional study. The distance from the buccal aspect of the IAN canal to the outer buccal cortical margin of the mandible in the mandibular second molar regions was measured on the computed tomography images. Also, the linear distance between the superior aspect of the IAN canal and the alveolar crest in these regions was calculated. In addition, we investigated the presence or absence of contact between the IAN canal and the inner buccal cortical margin of the mandible from the mandibular second molar to the mandibular foramen in the mandibular ramus. Next, we examined whether neurosensory disturbances occurring after SSRO were related to the position of the IAN at the mandibular second molar.
A significant difference was found in the occurrence of neurosensory disturbances of the IAN after SSRO between men and women (χ(2) test, P < .05). For the distance from the buccal aspect of the IAN canal to the outer buccal cortical margin of the mandible in the mandibular second molar region, a significant difference was found between groups with and without neurosensory disturbances (Student's t test, P < .01). The shorter the distance from the buccal aspect of the IAN canal to the outer buccal cortical margin, the more frequent the occurrence of neurosensory disturbances of the IAN.
The present results have demonstrated that gender and the anatomic position of the IAN canal at the mandibular second molar are significantly related to the occurrence of neurosensory disturbances of the IAN after SSRO. Therefore, surgeons should clearly inform patients of the increased possibility of neurosensory disturbances after SSRO when the patients are female and are found to have a shorter distance from the buccal aspect of the IAN canal to the outer buccal cortical margin.
Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 12/2010; 68(12):3022-7. · 1.58 Impact Factor
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Izumi Yoshioka,
Tatsurou Tanaka,
Amit Khanal,
Manabu Habu,
Shinji Kito,
Masaaki Kodama,
Masafumi Oda,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda, Yuji Seta,
Kazuhiro Tominaga,
Sumio Sakoda,
Yasuhiro Morimoto
[show abstract]
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ABSTRACT: Our aim was to find out whether the quality of bone around the inferior alveolar nerve is correlated with neurosensory disturbance to the nerve after sagittal split ramus osteotomy (SSRO) in patients with mandibular prognathism. Computed tomograms (CT) were taken of 35 patients with mandibular prognathism and 35 without. To assess the density of bone around the inferior alveolar nerve, the width of the buccal cortical bone in the mandibular second molar regions was measured on CT. The Hounsfield units (HU) in the same regions were also measured. The number of HU in the mandible around the second molar regions was significantly higher (p<0.01) in those with neurosensory disturbance (p<0.01). The quality of bone measured by HU is associated with an increased risk of neurosensory disturbance, but the width of buccal bone is not.
British Journal of Oral and Maxillofacial Surgery 11/2010; 49(7):552-6. · 1.95 Impact Factor
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Noriaki Yamamoto,
Yoshihiro Yamashita,
Tatsurou Tanaka,
Ayataka Ishikawa,
Shinji Kito,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda,
Masafumi Oda,
Ikuya Miyamoto,
Kensuke Yamauchi,
Shunji Shiiba, Yuji Seta,
Kou Matsuo,
Hirofumi Koga,
Tetsu Takahashi,
Yasuhiro Morimoto
[show abstract]
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ABSTRACT: To elucidate the clinical significance of imaging modalities for detection of stitch abscess after surgery in patients with oral squamous cell carcinoma (SCC). In 137 patients with oral SCC suspected of having lymph node metastases, local recurrence of tumor, or stitch abscess after surgery, the characteristic imaging findings related to lymph node metastases, local recurrence of tumor, and stitch abscess on ultrasonography (US), computed tomography (CT), magnetic resonance (MR), and (18)fluorodeoxyglucose (18FDG)-positron emission tomography (PET) images were identified and analyzed. In all six patients with stitch abscess, characteristic findings were demonstrated on US, different from those of metastatic lymph nodes and local recurrence on CT, MRI, and 18FDG-PET images. Our results suggest that ultrasonography may be a very useful tool for diagnosis of postoperative stitch abscess and may help improve the quality of life of oral SCC patients.
Oral Oncology 11/2010; 47(3):163-9. · 2.86 Impact Factor
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Nao Wakasugi-Sato,
Tetsuro Wakasugi,
Masafumi Oda,
Yoshihiro Yamashita,
Izumi Yoshioka,
Noriaki Yamamoto,
Manabu Habu,
Masaaki Kodama,
Shinya Kokuryo,
Hisashi Ichimiya,
Ikuya Miyamoto,
Tatsurou Tanaka,
Shinji Kito,
Shinobu Matsumoto-Takeda,
Ayataka Ishikawa, Yuji Seta,
Kou Matsuo,
Tetsu Takahashi,
Kazuhiro Tominaga,
Yasuhiro Morimoto
[show abstract]
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ABSTRACT: The objective of this study was to evaluate the clinical significance of ultrasonography (US) for screening for thyroid gland diseases when surveying the cervical lymph nodes to detect metastasis in subjects with oral squamous cell carcinoma (SCC).
The detection rates and characteristics of abnormal thyroid findings detected by US in 301 subjects with oral SCC were analyzed. Subjects with abnormal findings were referred to thyroid specialists and the diagnoses and treatments from these specialists were noted. The ratio of subjects who consulted a thyroid specialist after indications of thyroid gland abnormalities to analyze subject compliance was also examined. Follow-up examinations were regularly conducted to assess any changes in the thyroid gland.
Of the 301 subjects with oral SCC, 91 had abnormal thyroid gland findings on US. As subject age increased, the rate of detection of abnormal thyroid gland findings on US significantly increased. The rate of detection of abnormal findings in women by US was significantly higher than that in men, but the male-to-female ratio was lower compared with that in previous reports. It was demonstrated that oral SCC in the floor of the mouth was associated with the highest prevalence of abnormal findings in the thyroid gland (40%), followed by oral SCC of the maxillary gingiva (39%). Of the 91 subjects with abnormal findings, 10 showed enlargement in the size of the lesion on follow-up examination with US. Eleven subjects with no abnormal findings on initial examination showed abnormal findings on follow-up examination.
The results suggest that subjects with oral SCC have a relatively high rate of abnormal findings in the thyroid gland that can be detected by US. Scans that include the thyroid gland should be performed when surveying cervical lymph nodes for metastasis during US examination. Particular attention should be paid to thyroid gland-related diseases in older men who have oral cancer and to thyroid gland abnormalities if patients had oral SCC in the floor of the mouth or of the maxillary gingiva. It is recommended that follow-up US examinations be regularly performed in cases of oral SCC.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 06/2010; 109(6):e78-85. · 1.50 Impact Factor
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Nao Wakasugi-Sato,
Masaaki Kodama,
Kou Matsuo,
Noriaki Yamamoto,
Masafumi Oda,
Ayataka Ishikawa,
Tatsurou Tanaka, Yuji Seta,
Manabu Habu,
Shinya Kokuryo,
Hisashi Ichimiya,
Ikuya Miyamoto,
Shinji Kito,
Shinobu Matsumoto-Takeda,
Tetsuro Wakasugi,
Yoshihiro Yamashita,
Izumi Yoshioka,
Tetsu Takahashi,
Kazuhiro Tominaga,
Yasuhiro Morimoto
[show abstract]
[hide abstract]
ABSTRACT: Various kinds of diseases may be found in the oral and maxillofacial regions and various modalities may be applied for their diagnosis, including intra-oral radiography, panoramic radiography, ultrasonography, computed tomography, magnetic resonance imaging, and nuclear medicine methods such as positron emission tomography. Of these modalities, ultrasound imaging is easy to use for the detection of noninvasive and soft tissue-related diseases. Doppler ultrasound images taken in the B-mode can provide vascular information associated with the morphology of soft tissues. Thus, ultrasound imaging plays an important role in confirming the diagnosis of many kinds of diseases in such oral and maxillofacial regions as the tongue, lymph nodes, salivary glands, and masticatory muscles. In the present article, we introduce three new applications of ultrasonography: guided fine-needle aspiration, measurement of tongue cancer thickness, and diagnosis of metastasis to cervical lymph nodes.
International Journal of Dentistry 01/2010; 2010:639382.
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Shinji Kito,
Souichi Hirashima,
Izumi Yoshioka,
Manabu Habu,
Masaaki Kodama,
Shinya Kokuryo,
Masafumi Oda,
Tatsurou Tanaka,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda, Yuji Seta,
Kazuhiro Tominaga,
Yasuhiro Morimoto
[show abstract]
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ABSTRACT: Infectious arthritis of the temporomandibular joint (TMJ) is rare, and previous reports have identified malocclusion resulting from condylar deformity and displacement of the condyle as one of the clinical characteristics of the disease. Here we report the case of a 33-year-old man with chronic infectious arthritis of the TMJ without malocclusion associated with osteomyelitis of the right mandible. Based on radiological findings of more prominent inflammation at the TMJ than in other regions and on the observed efficacy of antibiotic administration, we made a diagnosis of suppurative arthritis of the TMJ. Based on our empirical experience, including the present case, we speculate that refusal to cooperate with medical care may be a factor in the development of infectious arthritis of the TMJ.
The Open Dentistry Journal 01/2010; 4:29-32.
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Yasuhiro Morimoto,
Tatsurou Tanaka,
Noriaki Yamamoto,
Masaaki Kodama, Yuji Seta,
Manabu Habu,
Masafumi Oda,
Shinji Kito,
Nao Wakasugi-Sato,
Shinobu Matsumoto-Takeda,
Yasuhiro Fukai,
Takatoshi Tokitsu,
Megumi Tomikawa,
Kazunari Matoba,
Yoshihiro Yamashita,
Izumi Yoshioka,
Tetsu Takahashi,
Kazuhiro Tominaga
[show abstract]
[hide abstract]
ABSTRACT: Various modalities are available for the diagnosis of diseases affecting the oral and maxillofacial regions. The currently used imaging modalities include intra-oral radiographs, panoramic radiographs, magnetic resonance imaging (MRI), computed tomography (CT) including cone-beam (CB) CT, ultrasonography (US), and nuclear medicine including positron emission tomography (PET). In the present review, we describe the application and significance of each modality in the diagnostic process of oral and maxillofacial diseases.
Current Medical Imaging Reviews 10/2009; 5(4):226-237. · 0.71 Impact Factor