Mary Fran Hazinski

Publications of Mary Fran Hazinski

• Importance and implementation of training in cardiopulmonary resuscitation and automated external defibrillation in schools: a science advisory from the American Heart Association.

  Authors: Diana M Cave, Tom P Aufderheide, Jeff Beeson, Alison Ellison, Andrew Gregory, Mary Fran Hazinski, Loren F Hiratzka, Keith G Lurie, Laurie J Morrison, Vincent N Mosesso, Vinay Nadkarni, Jerald Potts, Ricardo A Samson, Michael R Sayre, Stephen M Schexnayder

  Circulation. 02/2011; 123(6):691-706.

• Effect of defibrillation energy dose during in-hospital pediatric cardiac arrest.

  Authors: Peter A Meaney, Vinay M Nadkarni, Dianne L Atkins, Marc D Berg, Ricardo A Samson, Mary Fran Hazinski, Robert A Berg

  Pediatrics. 01/2011; 127(1):e16-23.

  To examine the effectiveness of initial defibrillation attempts. We hypothesized that (1) an initial shock dose of 2 ± 10 J/kg would be less effective for terminating fibrillation than suggested inTo examine the effectiveness of initial defibrillation attempts. We hypothesized that (1) an initial shock dose of 2 ± 10 J/kg would be less effective for terminating fibrillation than suggested in published historical data and (2) a 4 J/kg shock dose would be more effective. This was a National Registry of Cardiopulmonary Resuscitation prospective, multisite, observational study of in-hospital pediatric (aged ≤18 years) ventricular fibrillation or pulseless ventricular tachycardia cardiac arrests from 2000-2008. Termination of ventricular fibrillation or pulseless ventricular tachycardia and event survival after initial shocks of 2 J/kg were compared with historic controls and a 4 J/kg shock dose. Of 266 children with 285 events, 173 of 285 (61%) survived the event and 61 of 266 (23%) survived to discharge. Termination of fibrillation after initial shock was achieved for 152 of 285 (53%) events. Termination of fibrillation with 2 ± 10 J/kg was much less frequent than that seen among historic control subjects (56% vs 91%; P < .001), but not different than 4 J/kg. Compared with 2 J/kg, an initial shock dose of 4 J/kg was associated with lower rates of return of spontaneous circulation (odds ratio: 0.41 [95% confidence interval: 0.21-0.81]) and event survival (odds ratio: 0.42 [95% confidence interval: 0.18-0.98]). The currently recommended 2 J/kg initial shock dose for in-hospital cardiac arrest was substantially less effective than previously published. A higher initial shock dose (4 J/kg) was not associated with superior termination of ventricular fibrillation or pulseless ventricular tachycardia or improved survival rates. The optimal pediatric defibrillation dose remains unknown.

• Part 2: evidence evaluation and management of potential or perceived conflicts of interest: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Michael R Sayre, Robert E O'Connor, Dianne L Atkins, John E Billi, Clifton W Callaway, Michael Shuster, Brian Eigel, William H Montgomery, Robert W Hickey, Ian Jacobs, Vinay M Nadkarni, Peter T Morley, Tanya I Semenko, Mary Fran Hazinski

  Circulation. 11/2010; 122(18 Suppl 3):S657-64.

  In summary, the evidence review process has attempted to provide a systematic review of the scientific literature using a priori defined methods. The details and steps of the literature review areIn summary, the evidence review process has attempted to provide a systematic review of the scientific literature using a priori defined methods. The details and steps of the literature review are transparent and replicable. External opinions and community critique are highly valued, and the final products represent the combined labor of hundreds of participants.

• Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: John M Field, Mary Fran Hazinski, Michael R Sayre, Leon Chameides, Stephen M Schexnayder, Robin Hemphill, Ricardo A Samson, John Kattwinkel, Robert A Berg, Farhan Bhanji [......] Monica E Kleinman, Mark S Link, Laurie J Morrison, Robert E O'Connor, Michael Shuster, Clifton W Callaway, Brett Cucchiara, Jeffrey D Ferguson, Thomas D Rea, Terry L Vanden Hoek

  Circulation. 11/2010; 122(18 Suppl 3):S640-56.

  The goal of therapy for bradycardia or tachycardia is to rapidly identify and treat patients who are hemodynamically unstable or symptomatic due to the arrhythmia. Drugs or, when appropriate, pacingThe goal of therapy for bradycardia or tachycardia is to rapidly identify and treat patients who are hemodynamically unstable or symptomatic due to the arrhythmia. Drugs or, when appropriate, pacing may be used to control unstable or symptomatic bradycardia. Cardioversion or drugs or both may be used to control unstable or symptomatic tachycardia. ACLS providers should closely monitor stable patients pending expert consultation and should be prepared to aggressively treat those with evidence of decompensation.

• Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Robert A Berg, Robin Hemphill, Benjamin S Abella, Tom P Aufderheide, Diana M Cave, Mary Fran Hazinski, E Brooke Lerner, Thomas D Rea, Michael R Sayre, Robert A Swor

  Circulation. 11/2010; 122(18 Suppl 3):S685-705.

  The critical lifesaving steps of BLS are ● Immediate Recognition and Activation of the emergency response system ● Early CPR and ● Rapid Defibrillation for VF. When an adult suddenly collapses,The critical lifesaving steps of BLS are ● Immediate Recognition and Activation of the emergency response system ● Early CPR and ● Rapid Defibrillation for VF. When an adult suddenly collapses, whoever is nearby should activate the emergency system and begin chest compressions (regardless of training). Trained lay rescuers who are able and healthcare providers should provide compressions and ventilations. Contrary to the belief of too many in this situation, CPR is not harmful. Inaction is harmful and CPR can be lifesaving. However, the quality of CPR is critical. Chest compressions should be delivered by pushing hard and fast in the center of the chest (ie, chest compressions should be of adequate rate and depth). Rescuers should allow complete chest recoil after each compression and minimize interruptions in chest compressions. They should also avoid excessive ventilation. If and when available, an AED should be applied and used without delaying chest compressions. With prompt and effective provision of these actions, lives are saved every day.

• Part 7: CPR techniques and devices: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Diana M Cave, Raul J Gazmuri, Charles W Otto, Vinay M Nadkarni, Adam Cheng, Steven C Brooks, Mohamud Daya, Robert M Sutton, Richard Branson, Mary Fran Hazinski

  Circulation. 11/2010; 122(18 Suppl 3):S720-8.

  A variety of CPR techniques and devices may improve hemodynamics or short-term survival when used by well-trained providers in selected patients. All of these techniques and devices have theA variety of CPR techniques and devices may improve hemodynamics or short-term survival when used by well-trained providers in selected patients. All of these techniques and devices have the potential to delay chest compressions and defibrillation. In order to prevent delays and maximize efficiency, initial training, ongoing monitoring, and retraining programs should be offered to providers on a frequent and ongoing basis. To date, no adjunct has consistently been shown to be superior to standard conventional (manual) CPR for out-of-hospital basic life support, and no device other than a defibrillator has consistently improved long-term survival from out-of-hospital cardiac arrest.

• Part 11: adult stroke: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Edward C Jauch, Brett Cucchiara, Opeolu Adeoye, William Meurer, Jane Brice, Yvonne Yu-Feng Chan, Nina Gentile, Mary Fran Hazinski

  Circulation. 11/2010; 122(18 Suppl 3):S818-28.

  Advances in stroke care will have the greatest effect on stroke outcome if care is delivered within a regional stroke system designed to improve both efficiency and effectiveness. The ultimate goalAdvances in stroke care will have the greatest effect on stroke outcome if care is delivered within a regional stroke system designed to improve both efficiency and effectiveness. The ultimate goal of stroke care is to minimize ongoing injury, emergently recanalize acute vascular occlusions, and begin secondary measures to maximize functional recovery. These efforts will provide stroke patients with the greatest opportunity for a return to previous quality of life and decrease the overall societal burden of stroke.

• Part 13: pediatric basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Marc D Berg, Stephen M Schexnayder, Leon Chameides, Mark Terry, Aaron Donoghue, Robert W Hickey, Robert A Berg, Robert M Sutton, Mary Fran Hazinski

  Circulation. 11/2010; 122(18 Suppl 3):S862-75.

• Part 14: pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Monica E Kleinman, Leon Chameides, Stephen M Schexnayder, Ricardo A Samson, Mary Fran Hazinski, Dianne L Atkins, Marc D Berg, Allan R de Caen, Ericka L Fink, Eugene B Freid, Robert W Hickey, Bradley S Marino, Vinay M Nadkarni, Lester T Proctor, Faiqa A Qureshi, Kennith Sartorelli, Alexis Topjian, Elise W van der Jagt, Arno L Zaritsky

  Circulation. 11/2010; 122(18 Suppl 3):S876-908.

• Part 15: neonatal resuscitation: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: John Kattwinkel, Jeffrey M Perlman, Khalid Aziz, Christopher Colby, Karen Fairchild, John Gallagher, Mary Fran Hazinski, Louis P Halamek, Praveen Kumar, George Little, Jane E McGowan, Barbara Nightengale, Mildred M Ramirez, Steven Ringer, Wendy M Simon, Gary M Weiner, Myra Wyckoff, Jeanette Zaichkin

  Circulation. 11/2010; 122(18 Suppl 3):S909-19.

• Part 16: education, implementation, and teams: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Farhan Bhanji, Mary E Mancini, Elizabeth Sinz, David L Rodgers, Mary Ann McNeil, Theresa A Hoadley, Reylon A Meeks, Melinda Fiedor Hamilton, Peter A Meaney, Elizabeth A Hunt, Vinay M Nadkarni, Mary Fran Hazinski

  Circulation. 11/2010; 122(18 Suppl 3):S920-33.

  Optimizing the links in the Chain of Survival improves outcomes and saves lives. The use of evidence-based education and implementation strategies will allow organizations and communities toOptimizing the links in the Chain of Survival improves outcomes and saves lives. The use of evidence-based education and implementation strategies will allow organizations and communities to strengthen these links in the most effective and efficient manner.

• Part 6: Defibrillation: 2010 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations.

  Authors: Kjetil Sunde, Ian Jacobs, Charles D Deakin, Mary Fran Hazinski, Richard E Kerber, Rudolph W Koster, Laurie J Morrison, Jerry P Nolan, Michael R Sayre

  Resuscitation. 10/2010; 81 Suppl 1:e71-85.

• Part 5: Adult basic life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

  Authors: Michael R Sayre, Rudolph W Koster, Martin Botha, Diana M Cave, Michael T Cudnik, Anthony J Handley, Tetsuo Hatanaka, Mary Fran Hazinski, Ian Jacobs, Koen Monsieurs, Peter T Morley, Jerry P Nolan, Andrew H Travers

  Circulation. 10/2010; 122(16 Suppl 2):S298-324.

• Part 6: Defibrillation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

  Authors: Ian Jacobs, Kjetil Sunde, Charles D Deakin, Mary Fran Hazinski, Richard E Kerber, Rudolph W Koster, Laurie J Morrison, Jerry P Nolan, Michael R Sayre

  Circulation. 10/2010; 122(16 Suppl 2):S325-37.

• Pediatric basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

  Authors: Marc D Berg, Stephen M Schexnayder, Leon Chameides, Mark Terry, Aaron Donoghue, Robert W Hickey, Robert A Berg, Robert M Sutton, Mary Fran Hazinski

  Pediatrics. 10/2010; 126(5):e1345-60.

• Part 5: Adult basic life support: 2010 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations.

  Authors: Rudolph W Koster, Michael R Sayre, Martin Botha, Diana M Cave, Michael T Cudnik, Anthony J Handley, Tetsuo Hatanaka, Mary Fran Hazinski, Ian Jacobs, Koen Monsieurs, Peter T Morley, Jerry P Nolan, Andrew H Travers

  Resuscitation. 10/2010; 81 Suppl 1:e48-70.

• Part 4: Conflict of interest management before, during, and after the 2010 International Consensus Conference on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

  Authors: Michael Shuster, John E Billi, Leo Bossaert, Allan R de Caen, Charles D Deakin, Brian Eigel, Mary Fran Hazinski, Robert W Hickey, Ian Jacobs, Monica E Kleinman [......] Henrietta Munoz, Vinay M Nadkarni, Jerry P Nolan, Robert E O'Connor, Jeffrey M Perlman, Sam Richmond, Michael R Sayre, Jasmeet Soar, Jonathan Wyllie, David Zideman

  Resuscitation. 10/2010; 81 Suppl 1:e41-7.

• Part 12: Education, implementation, and teams: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

  Authors: Jasmeet Soar, Mary E Mancini, Farhan Bhanji, John E Billi, Jennifer Dennett, Judith Finn, Matthew Huei-Ming Ma, Gavin D Perkins, David L Rodgers, Mary Fran Hazinski, Ian Jacobs, Peter T Morley

  Resuscitation. 10/2010; 81 Suppl 1:e288-330.

• Part 11: Neonatal resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

  Authors: Jonathan Wyllie, Jeffrey M Perlman, John Kattwinkel, Dianne L Atkins, Leon Chameides, Jay P Goldsmith, Ruth Guinsburg, Mary Fran Hazinski, Colin Morley, Sam Richmond, Wendy M Simon, Nalini Singhal, Edgardo Szyld, Masanori Tamura, Sithembiso Velaphi

  Resuscitation. 10/2010; 81 Suppl 1:e260-87.

• Part 2: International collaboration in resuscitation science: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

  Authors: Jerry P Nolan, Vinay M Nadkarni, John E Billi, Leo Bossaert, Bernd W Boettiger, Douglas Chamberlain, Saul Drajer, Brian Eigel, Mary Fran Hazinski, Robert W Hickey, Ian Jacobs, Walter Kloeck, William H Montgomery, Peter T Morley, Robert E O'Connor, Kazuo Okada, Michael Shuster, Andrew H Travers, David Zideman

  Resuscitation. 10/2010; 81 Suppl 1:e26-31.