Neil S Sharma

Macquarie University Hospital, Macquarie, Australian Capital Territory, Australia

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Publications (13)118.83 Total impact

  • Neil S Sharma, Maria Z Li, Ju-Lee Ooi
    Australian Journal of Rural Health 04/2012; 20(2):97-8. · 1.55 Impact Factor
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    Neil S Sharma, Ju-Lee Ooi, Maria Z Li
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    ABSTRACT: A man, 75 years of age, presents with a red, painful, watery right eye of 1 week duration. He describes photophobia but says his vision is not reduced or blurry. He was seen at another clinic after 2 days of symptoms and was prescribed topical chloramphenicol antibiotic eye drops. Despite using the eye drops for 5 days, there has been no improvement in his symptoms. The man has no significant ocular past history.
    Australian family physician 10/2009; 38(10):805-7. · 0.71 Impact Factor
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    ABSTRACT: Crystalline keratopathy can be successfully treated by the Nd:YAG laser. We present two cases of crystalline keratopathy managed this way. A 36-year-old female contact lens wearer presented with crystalline keratopathy following recent treatment with topical steroids and antibiotics for a corneal abscess. In this case crystalline keratopathy developed despite the intensive topical antibiotic treatment. A 55-year-old man with a history of acne rosacea, chronic myelomonocytic leukaemia, asthma and Crohn's disease presented with crystalline keratopathy following an episode of infectious keratitis. Treatment with the Nd:YAG laser to the area of involvement was instituted in both cases. Noticeable resolution occurred within days, with subsequent full recovery. No side-effects from the use of the Nd:YAG laser were noted. There have been only two cases previously reported using this treatment modality.
    Clinical and Experimental Ophthalmology 04/2009; 37(2):177-80. · 1.96 Impact Factor
  • The Medical journal of Australia 11/2008; 189(7):413. · 2.85 Impact Factor
  • New England Journal of Medicine 10/2008; 359(13):1410-1. · 54.42 Impact Factor
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    ABSTRACT: Ipratropium bromide is a commonly used bronchodilator which has been rarely reported to cause pharmacological mydriasis. We report a 22-year-old woman using 6-hourly nebulised ipratropium from a multi-dose preparation, who presented with a unilateral dilated pupil which resolved spontaneously over 24h after discontinuation of her ill-fitting nebuliser mask which had been directing the drug toward that eye. No alternative cause was found despite extensive investigations. Greater recognition of this iatrogenic cause of reversible pupillary dilatation may avoid the need for unnecessary investigations.
    Journal of Clinical Neuroscience 04/2008; 15(3):320-1. · 1.25 Impact Factor
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    ABSTRACT: To compare temporal artery biopsy specimen lengths from a tertiary care and a community hospital in New South Wales to recommended clinical guidelines in suspected giant cell arteritis. A retrospective observational study of all patients who underwent temporal artery biopsy at Bathurst Base Hospital (BBH) and Royal Prince Alfred Hospital (RPAH) over a 5-year period. Patients who underwent temporal artery biopsy during the 5-year period were identified using computerized hospital databases. A retrospective chart review was carried out on all cases. Data were collected regarding patient age, patient sex, length of biopsy specimen, histopathological results and surgical team carrying out the biopsy. During the 5-year period, 157 temporal artery biopsies were carried out at both hospitals, with 38/157(24%) at BBH and 119/157 (76%) at RPAH. There was no significant difference in biopsy length at the two hospitals. The mean specimen length at BBH was 12.1 mm compared with 11.7 mm at RPAH (t=0.35; P=0.73). At RPAH, there was no significant difference in specimen length between the surgical specialties carrying out the biopsy (ANOVA F=1.37; P=0.26). Specimens of length 20 mm or greater were 2.8 times more likely to show features of giant cell arteritis than those less than 20 mm. The mean length of temporal artery biopsy specimens at both hospitals was substantially shorter than recommended guidelines of a minimum 20 mm. We recommend all surgeons carrying out temporal artery biopsies ensure a specimen of sufficient length is obtained.
    ANZ Journal of Surgery 07/2007; 77(6):437-9. · 1.50 Impact Factor
  • Journal of Cataract and Refractive Surgery 06/2007; 33(5):757-8. · 2.53 Impact Factor
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    ABSTRACT: Hydroxyapatite orbital implants are widely used in enucleation surgery. Infection in this setting is an uncommon but severe complication. Herein a patient with a 3-year history of chronic socket discharge, orbital discomfort, conjunctival breakdown and implant exposure after enucleation and implantation of a hydroxyapatite sphere 7 years previously is reported. Repeated attempts at covering the exposed implant failed. Eventually the implant was removed, and Aspergillus fumigatus was cultured from the explanted material. This is the second reported case of Aspergillus infection of a hydroxyapatite orbital implant, and the first case where fungal cultures were positive.
    Clinical and Experimental Ophthalmology 05/2007; 35(3):294-5. · 1.96 Impact Factor
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    ABSTRACT: To investigate established pterygia using our newly developed ultraviolet fluorescence photography (UVFP) system. Prospective observational case series. setting: Prince of Wales Hospital, Sydney, Australia. study population: Fourteen patients (both eyes) attending the Ophthalmology Clinic at Prince of Wales Hospital for assessment of their established pterygia. There were eight men and six women, with an age range of 26 to 62 years. A total of 15 (75%) of 20 had primary pterygia, and five (25%) of 20 had recurrent pterygia. There were no specific exclusion criteria. observation procedures: Ultraviolet and standard (control) photographs were taken of the nasal and temporal interpalpebral regions bilaterally. main outcome measures: The presence of established pterygia detected by standard photography and the corresponding presence and patterns of areas of fluorescence detected by UVFP. In the 14 patients, 20 established pterygia were identified on standard photography. On UVFP, four patterns of fluorescence of established pterygia were identified. Of the 20 pterygia, six (30%) of 20 demonstrated fluorescence at the leading edge of the pterygium, seven (35%) of 20 demonstrated fluorescence at the limbus, three (15%) of 20 demonstrated fluorescence at both the leading edge and the limbus, and four (20%) of 20 demonstrated no visible fluorescence. In this study, we describe patterns of fluorescence in established pterygia by UVFP. We hypothesize that the areas of fluorescence represent areas of cellular activity within the pterygium. The patterns of fluorescence may be useful to further understand of pterygium growth and pathogenesis.
    American Journal of Ophthalmology 02/2007; 143(1):97-101. · 4.02 Impact Factor
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    ABSTRACT: To develop a method to detect precursors of ocular sun damage using ultraviolet fluorescence photography (UVFP). Observational cross-sectional study settings: Preschool, primary, and high school in Sydney, Australia. study population: 71 children ages 3 to 15 years old (both eyes). Inclusion criteria were children attending the schools who gave consent. There were no exclusion criteria. observation procedures: UV and standard (control) photographs were taken of the nasal and temporal interpalpebral regions bilaterally. main outcome measures: Presence of areas of increased fluorescence detected by UVFP, or presence of pinguecula detected by standard photography. Established pingueculae, on standard photography, were seen in seven of 71 (10%) children; all were 13 years of age or older. On UVFP, all of these pingueculae demonstrated fluorescence. In total, 23 of 71 (32%) had increased fluorescence detected on UVFP, including the seven of 23 (30%) with pingueculae. Of the remaining 16 of 23 (70%), the changes were only detectable using UVFP. Fluorescence on UVFP was seen in children ages 9 years and above, with prevalence increasing with age. The presence of fluorescence (in at least one region) was 0 of 15 (0%) for children ages 3 to 5 years, 0 of 12 (0%) of children ages 6 to 8 years, 6 of 23 (26%) for those ages 9 to 11 years, and 17 of 21 (81%) of those ages 12 to 15 years. We hypothesize that the areas seen to fluoresce on UVFP but not detectable on control photography represent precursors for ophthalmohelioses. Our preliminary data strongly suggests that UVFP is a sensitive method for detecting early ocular sun damage occurring many years before clinical manifestations.
    American Journal of Ophthalmology 03/2006; 141(2):294-8. · 4.02 Impact Factor
  • The Lancet 01/2004; 364(9432):415; author reply 415. · 39.21 Impact Factor
  • Neil S Sharma
    The Medical journal of Australia 189(11-12):669. · 2.85 Impact Factor

Publication Stats

70 Citations
118.83 Total Impact Points

Institutions

  • 2012
    • Macquarie University Hospital
      Macquarie, Australian Capital Territory, Australia
    • University of Wollongong
      • Graduate School of Medicine
      City of Greater Wollongong, New South Wales, Australia
  • 2009
    • University of Sydney
      Sydney, New South Wales, Australia
  • 2008
    • Sydney Hospital & Sydney Eye Hospital
      Sydney, New South Wales, Australia
  • 2007
    • Royal Prince Alfred Hospital
      Camperdown, New South Wales, Australia
  • 2006
    • University of New South Wales
      • Prince of Wales Hospital
      Kensington, New South Wales, Australia