E Sgnaolin

Publications (4)11.15 Total impact

• Article: Guar‐enriched pasta and guar gum in the dietary treatment of type II diabetes

  G. Briani, D. Bruttomesso, G. Bilardo, C. Giorato, E. Duner, E. Iori, E. Sgnaolin, P. Pedrini, A. Tiengo
  [show abstract] [hide abstract]
  ABSTRACT: Guar gum in two forms of preparation decreased post-prandial glycemic profiles in patients when compared to controls. No differences were observed between the two guar gum preparations and no significant changes were exhibited in the FFA, lactate or pyruvate areas. From IRI and C-peptide curves the preparations containing guar gum produced slower and later responses when compared to controls. 30% of patients reported diarrhea after consumption of one guar gum preparation and 60% of patients found that one preparation was not palatable whereas the other preparation was considered to be pleasant.
  Phytotherapy Research 01/2006; 1(4):177 - 179. · 2.09 Impact Factor
• Article: Renal hemodynamics and albumin excretion rate in patients with diabetes secondary to acquired pancreatic disease.

  A Tiengo, G Briani, E Scaldaferri, F Riva, E Jori, E Sgnaolin, R Fenato, M D'Ambrosio, P Fioretto, R Nosadini
  [show abstract] [hide abstract]
  ABSTRACT: OBJECTIVE--To assess kidney function and AER in patients with PD. RESEARCH DESIGN AND METHODS--Thirty-three patients with PD (age 52 +/- 7 yr, duration of disease 11 +/- 6 yr, BMI 24 +/- 3 kg/m2) and 33 patients with IDDM were matched for sex, BMI, and duration of disease. GFR and RPF were determined by single injection of [51Cr]EDTA and [125I]hippurate. AER was measured by radioimmunoassay in a single timed overnight urine collection. RESULTS--GFR and RPF were, respectively, 113 +/- 35 and 441 +/- 145 ml.min-1.73 m2 in patients with PD and 123 +/- 30 and 549 +/- 94 (P < 0.001) in IDDM. FF was significantly higher in patients with PD (0.26 +/- 0.05 vs. 0.22 +/- 0.03; P < 0.001). Prevalence of hyperfiltration (GFR > 135 ml.min-1.1.73 m2) was similar in both groups (30% in patients with PD vs. 28% in those with IDDM). Geometric mean of urinary AER was 10.4 micrograms/min (range 1-186) in patients with PD and 11.2 (1-198) in IDDM patients. Some 30.3% of patients with PD and 18% of those with IDDM were microalbuminuric (AER > 20 micrograms/min). By multiple regression analysis, AER was significantly related to systolic (P < 0.04) and diastolic blood pressure (P < 0.01) and to BMI (P < 0.03) in patients with PD. Retinopathy was more frequent in microalbuminuric patients with PD than in those without elevated AER. CONCLUSIONS--We suggest that early renal abnormalities occur similarly in patients with PD and IDDM.
  Diabetes Care 12/1992; 15(11):1591-7. · 8.09 Impact Factor
• Article: Prevalence of microangiopathic complications in hyperglycemia secondary to pancreatic disease.

  G Briani, F Riva, E Midena, R Trevisan, E Sgnaolin, E Jori, R Munari, D Bruttomesso, T Segato, A Tiengo
  [show abstract] [hide abstract]
  ABSTRACT: Diabetes secondary to pancreatic disease (PD) represents a useful model for the study of the effects of chronic hyperglycemia on microangiopathic complications in the absence of those genetic factors predisposing to Type I diabetes. Our aim was to evaluate the prevalence of nephropathy and retinopathy in a group of 86 patients with PD. The genetic pattern, assessed by the determination of HLA antigens, was different than in patients with Type I diabetes. A family history of diabetes was present in 53% of the patients. The prevalence of retinopathy was 37%. Eighteen percent of the patients with duration of diabetes less than 10 years showed an albumin excretion rate (AER) greater than 40 mg/24 hr. The prevalence of pathologic microalbuminuria (greater than 40 mg/24 hr) was found in 29% of the patients with duration of diabetes greater than 10 years. The prevalence of pathologic microalbuminuria is related to the duration of diabetes. Both diastolic and systolic blood pressure is positively correlated to albumin excretion rate (p less than 0.02), suggesting a possible role of hypertension in the evolution of nephropathy. Sixty-one percent of the patients with AER greater than 40 mg/24 h had retinopathy, thus confirming the close association between renal and ocular complications. Abnormal microalbuminuria and retinopathy were not influenced by a family history of diabetes. We conclude that the prevalence of microangiopathic complications is similar to that seen in Type I diabetes, and the metabolic abnormalities of diabetes can play a direct role in the development of diabetic microangiopathy.
  Journal of Diabetic Complications 2(1):50-2.
• Article: [Early urinary markers of renal involvement in diabetic nephropathy].

  G Briani, B Baggio, D Bruttomesso, M R Munari, E Iori, E Cicerello, G Gambaro, E Duner, E Sgnaolin, A Tiengo
  Minerva endocrinologica 12(2):149-52. · 0.98 Impact Factor