Purificación Gómez Jara

Universidad Católica San Antonio de Murcia, Murcia, Murcia, Spain

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Publications (25)20.07 Total impact

  • SEMERGEN - Medicina de Familia 01/2015;
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    ABSTRACT: Background and objectives 1) Nutritional assessment of the diet followed by patients with metabolic syndrome, and 2) biochemical analysis of the oxidation-reduction level in patients with metabolic syndrome. Material and methods A cross-sectional study was conducted in patients with metabolic syndrome in Murcia. Fifty-three patients, 33 with and 20 without (control group) metabolic syndrome, were selected. The intervention consisted of completion of a recall survey and a test to nutritionally assess dietary intake. Anthropometric and laboratory variables, including those related to antioxidant activity, were also tested. Results Antioxidant activity was within normal limits in both groups (1.7 ± 0.2 mmol/L in the control group and 1.8 ± 0.1 mmol/L in the metabolic syndrome group) (NS). Superoxide dismutase levels were not significantly different between the groups. Mean glutathione reductase levels (U/L) were higher in the control group as compared to patients with metabolic syndrome (P < .05). As regards oxidative stress biomarkers, mean isoprostane levels were higher in the control group (4.9 ± 6.2 ng/mL) than in metabolic syndrome patients (3.5 ± 3.9 ng/mL) (P < .05). Oxidized LDL values tended to be higher in metabolic syndrome patients (96 ± 23.2 U/L) as compared to the control group (86.2 ± 17.3 U/L), but differences were not significant. Conclusions There is a trend to a poorer nutritional and biochemical profile in patients with metabolic syndrome, who also tend to have a greater degree of oxidative stress.
    Endocrinología y Nutrición 06/2014; DOI:10.1016/j.endonu.2014.01.006
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    ABSTRACT: 1) Nutritional assessment of the diet followed by patients with metabolic syndrome, and 2) biochemical analysis of the oxidation-reduction level in patients with metabolic syndrome. A cross-sectional study was conducted in patients with metabolic syndrome in Murcia. Fifty-three patients, 33 with and 20 without (control group) metabolic syndrome, were selected. The intervention consisted of completion of a recall survey and a test to nutritionally assess dietary intake. Anthropometric and laboratory variables, including those related to antioxidant activity, were also tested. Antioxidant activity was within normal limits in both groups (1.7±0.2mmol/L in the control group and 1.8±0.1mmol/L in the metabolic syndrome group) (NS). Superoxide dismutase levels were not significantly different between the groups. Mean glutathione reductase levels (U/L) were higher in the control group as compared to patients with metabolic syndrome (P<.05). As regards oxidative stress biomarkers, mean isoprostane levels were higher in the control group (4.9±6.2ng/mL) than in metabolic syndrome patients (3.5±3.9ng/mL) (P<.05). Oxidized LDL values tended to be higher in metabolic syndrome patients (96±23.2U/L) as compared to the control group (86.2±17.3 U/L), but differences were not significant. There is a trend to a poorer nutritional and biochemical profile in patients with metabolic syndrome, who also tend to have a greater degree of oxidative stress.
    Endocrinología y Nutrición 02/2014;
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    ABSTRACT: To analyze the lifestyles associated with cardiovascular risk in a university population in university admission. A descriptive, observational, cross-sectional students of the Catholic University San Antonio of Murcia. Select a sample of 672 college students enrolled in the first year of the race. The instrument used to collect the data, is a self-completed questionnaire anonymous, with a total of 59 questions. With respect to smoking 242 are smokers (36%), 117 former smokers (17.4%), and 313 non-smokers (46.6%). When compared snuff consumption by sex, no differences are detected. By running the largest group of non-smokers often seen in students of physical sciences (59.1%) compared to the careers humanities (40.9%). 87.4% (587) of students surveyed report using alcohol, compared to 12.6% (85) no. According to the race group not detected association between race group and the fact consume alcohol or not. The 65.6% of students surveyed physical exercise commonly referred, being higher the frequency of exercise in men than in women (81.7% versus 49.4%) (P<.001). 54.3% of surveyed students follow a dietary pattern typical of the Mediterranean diet. The University does not exercise the role that could mean in terms of enhancing healthy lifestyles and abandonment of harmful health styles.
    Clinica e Investigacion en Arteriosclerosis 12/2013;
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    ABSTRACT: Objective To determine whether a stay in a treatment center with thermal and sulfur mineral water and topically applied peloids correlates with changes in blood pressure. Design Observational study of a cohort of individuals. Participants A total of 53 individuals. There was no age range and both hypertensive and non-hypertensive individuals were evaluated. Method Before and after balneotherapy, a total of 18 self blood-pressure measurements were taken, as well an isolated clinical blood pressure measurement (seated and standing). We also conducted a survey to evaluate adherence to the Mediterranean diet. Scores ranged from 0 points (non-adherence) and 10 points (complete adherence). Results Clinical measurement: systolic blood pressure (SBP) was 133.0 ± 13.9 mm Hg at baseline and 126.5 ± 12.3 mm Hg (P=.015) at the end of the study. The mean diastolic blood pressure (DBP) was 78.5 ± 7.8 mm Hg at baseline and 75.9 ± 6.5 mm Hg (ns) at the end of the study. Self-monitored blood pressure: The mean SBP after treatment was 2.3 mm Hg lower than before treatment (P=.008). The mean DBP was 1.1 mm Hg lower after treatment than before treatment (ns). Conclusions A 10-day stay in a spa with sulfur water correlates with decreased blood pressure mainly due to the decrease in SBP.
    Hipertensión y Riesgo Vascular 07/2013; 30(3):86–91. DOI:10.1016/j.hipert.2013.04.002
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    ABSTRACT: Objective To assess whether there are differences in the immigrant population in terms of the years since their arrival in Spain and their geographical area of origin.DesignA cross-sectional study was conducted in three immigrant groups.ParticipantsThe groups selected were: a group of Latin American immigrants (298), a group of North African immigrants (130) and a group from Eastern Europe (114). A control group of 100 from a Spanish population of similar age and sex was also included.Methods Anthropometric variables were measured, including biochemical inflammatory markers, blood pressure and cardiovascular risk estimation according to the tables of the European Societies of Hypertension and Cardiology.ResultsThe cardiovascular risk of the three groups of immigrants is similar between them (added cardiovascular risk high or very high at 5.5% in Latin Americans, 4.3% in North Africans, and 1.6% in immigrants from eastern countries), but significantly lower than the Spanish control group (28%). After 8 years in Spain, cardiovascular risk increases in the three groups of immigrants, with those from North Africa and eastern countries being comparable to the Spanish group (added cardiovascular risk high or very high of 18.5% in North Africans, and 20% in group from eastern countries). This cardiovascular risk was higher than the other groups, including the Spanish control group (Latin American immigrants 48.7% vs 28% in Spanish group).Conclusions The cardiovascular risk of immigrants increases over the years in Spain, with this increase being higher if they come from Latin America. This increase becomes clinically significant after the 8 years of stay in Spain.
    Atención Primaria 02/2013; 45(2):92–100. DOI:10.1016/j.aprim.2012.10.003 · 0.89 Impact Factor
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    ABSTRACT: Objective To analyze the lifestyles associated with cardiovascular risk in a university population in university admission. Material and methods A descriptive, observational, cross-sectional students of the Catholic University San Antonio of Murcia. Select a sample of 672 college students enrolled in the first year of the race. The instrument used to collect the data, is a self-completed questionnaire anonymous, with a total of 59 questions. Results With respect to smoking 242 are smokers (36%), 117 former smokers (17.4%), and 313 non-smokers (46.6%). When compared snuff consumption by sex, no differences are detected. By running the largest group of non-smokers often seen in students of physical sciences (59.1%) compared to the careers humanities (40.9%). 87.4% (587) of students surveyed report using alcohol, compared to 12.6% (85) no. According to the race group not detected association between race group and the fact consume alcohol or not. The 65.6% of students surveyed physical exercise commonly referred, being higher the frequency of exercise in men than in women (81.7% versus 49.4%) (P < .001). 54.3% of surveyed students follow a dietary pattern typical of the Mediterranean diet. Conclusions The University does not exercise the role that could mean in terms of enhancing healthy lifestyles and abandonment of harmful health styles.
    Clínica e Investigación en Arteriosclerosis 01/2013; DOI:10.1016/j.arteri.2013.10.007
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    ABSTRACT: OBJECTIVE: To assess whether there are differences in the immigrant population in terms of the years since their arrival in Spain and their geographical area of origin. DESIGN: A cross-sectional study was conducted in three immigrant groups. PARTICIPANTS: The groups selected were: a group of Latin American immigrants (298), a group of North African immigrants (130) and a group from Eastern Europe (114). A control group of 100 from a Spanish population of similar age and sex was also included. METHODS: Anthropometric variables were measured, including biochemical inflammatory markers, blood pressure and cardiovascular risk estimation according to the tables of the European Societies of Hypertension and Cardiology. RESULTS: The cardiovascular risk of the three groups of immigrants is similar between them (added cardiovascular risk high or very high at 5.5% in Latin Americans, 4.3% in North Africans, and 1.6% in immigrants from eastern countries), but significantly lower than the Spanish control group (28%). After 8 years in Spain, cardiovascular risk increases in the three groups of immigrants, with those from North Africa and eastern countries being comparable to the Spanish group (added cardiovascular risk high or very high of 18.5% in North Africans, and 20% in group from eastern countries). This cardiovascular risk was higher than the other groups, including the Spanish control group (Latin American immigrants 48.7% vs 28% in Spanish group). CONCLUSIONS: The cardiovascular risk of immigrants increases over the years in Spain, with this increase being higher if they come from Latin America. This increase becomes clinically significant after the 8 years of stay in Spain.
    Atención Primaria 11/2012; · 0.89 Impact Factor
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    ABSTRACT: Objectives1) To assess the monitoring of non-pharmacological recommendations for the treatment of hypertension. 2) Analyse the relationship between monitoring and non-pharmacological blood pressure control.
    SEMERGEN - Medicina de Familia 10/2011; 37(8):398-404. DOI:10.1016/j.semerg.2011.02.007
  • Journal of Hypertension 01/2011; 29:e539-e540. DOI:10.1097/00004872-201106001-01638 · 4.22 Impact Factor
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    ABSTRACT: Objectives Analyze if the factors that determine competitiveness between couples are associated to greater cardiovascular risk (CVR) in the male. Evaluate if the behavior model and quality of life are correlated with CVR.
    Hipertensión y Riesgo Vascular 11/2010; 27(6):233-238. DOI:10.1016/j.hipert.2010.05.003
  • Journal of Hypertension 01/2010; 28. DOI:10.1097/01.hjh.0000379203.38658.83 · 4.22 Impact Factor
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    ABSTRACT: Introduction1) To know the course over 5 years presented by patients who have suffered a hypertensive crisis. 2) To analyze whether these hypertensive crisis represent an increased risk of cardiovascular events in 5 years compared to hypertensive subjects with no hypertensive crisis.
    Hipertensión y Riesgo Vascular 11/2009; 26(6). DOI:10.1016/j.hipert.2009.04.002
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    ABSTRACT: To analyse the influence of a physical exercise programme of strength/stamina on cardiovascular risk factors in low-risk post-menopausal women. Six-month randomised clinical trial with post-menopausal women. Three health centres in the autonomous community of Murcia, Spain. Sixty-three post-menopausal women aged 45 to 59 at low cardiovascular risk. INTERVENTIONS AND MAIN MEASUREMENTS: They were split into 2 groups: a) control: 23 people with no specific intervention, and b) 40 people with an intervention of strength/stamina exercise with protocol for in water and on land. At their initial and final visits, everyone in the 2 groups had anamnesis, physical examination, and general analyses, including Apo A, Apo B, insulin, serum creatinine, creatinine clearance, creatinine in urine, albuminuria, ultrasensitive PCR, and HOMA index. The insulin levels increased in the control group by 2.02 mU/L and dropped in the experimental group by 0.13 mU/L (P=.021). At the start of the study, creatinine in the control group was 0.83+/-0.12 mg/dL; and at the end, 0.91+/-0.02 mg/dL. In the intervention group it was 0.84+/-0.12 mg/dL at the start and 0.90+/-0.13 mg/dL at the end (NS). Systolic blood pressure dropped in both groups, with a bigger drop in the exercise group (11.81 vs 0.17 mm Hg) (P=.0001). HDL-C values increased in the control group by 4.97 mg/dL; and in the experimental group, by 3.46 mg/dL (NS). A controlled programme of strength/stamina physical exercise reduces the cardiovascular risk of post-menopausal women.
    Atención Primaria 08/2008; 40(7):351-6. · 0.89 Impact Factor
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    ABSTRACT: Objective To analyse the influence of a physical exercise programme of strength/stamina on cardiovascular risk factors in low-riskpost-menopausal women. Design Six-month randomised clinical trial with post-menopausal women. Setting Three health centres in the autonomous community of Murcia, Spain. Participants Sixty-three post-menopausal women aged 45 to 59 at low cardiovascular risk. Interventions and main measurements They were split into 2 groups: a) control: 23 people with no specific intervention, and b) 40 people with an intervention of strength/stamina exercise with protocol for in water and on land. At their initial and final visits, everyone in the 2 groups had anamnesis, physical examination, and general analyses, including Apo A, Apo B, insulin, serum creatinine, creatinine clearance, creatinine in urine, albuminuria, ultrasensitive PCR, and HOMA index. Results The insulin levels increased in the control group by 2.02 mU/L and dropped in the experimental group by 0.13 mU/L (P=.021). Atthe start ofthe study, creatinine in the control group was 0.83±0.12 mg/dL; and atthe end, 0.91±0.02 mg/dL. In the intervention group it was 0.84±0.12 mg/dL at the start and 0.90±0.13 mg/dL atthe end (NS). Systolic blood pressure dropped in both groups, with a bigger drop in the exercise group (11.81 vs 0.17 mm Hg) (P=.0001). HDL-C values increased in the control group by 4.97 mg/dL; and in the experimental group, by 3.46 mg/dL (NS). Conclusions A controlled programme of strength/stamina physical exercise reduces the cardiovascular risk of post-menopausal women.
    Atención Primaria 07/2008; 40(7):351-356. DOI:10.1157/13124128 · 0.89 Impact Factor
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    Atención Primaria 02/2008; 40(1):43. · 0.89 Impact Factor
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    ABSTRACT: La asociación de diabetes e hipertensión arterial (HTA) es muy frecuente y en ella influyen mecanismos fisiopatológicos comunes en su desarrollo. La prevalencia de HTA en el paciente diabético es dos o tres veces superior que en las personas no diabéticas de iguales características. Alrededor del 40-50% de los diabéticos son hipertensos y la prevalencia aumenta con la edad, el peso, la duración de la diabetes, la proteinuria y la disminución de la función renal1-3. Objetivos Describir los factores de riesgo cardiovascular en hipertensos diabéticos seguidos en atención primaria y analizar su grado de control. Diseño Estudio descriptivo realizado en junio y julio de 2006. Emplazamiento Doce centros de salud de la Comunidad Autónoma de Murcia. Participantes Se incluyó a 150 pacientes (73 varones y 77 mujeres), con edades entre 40 y 75 años, con el diagnóstico conjunto de hipertensión arterial y diabetes mellitus tipo 2 y que acudieron a consulta médica por cualquier motivo. Mediciones principales Se determinó la presión arterial según las normas aceptadas por la SEH-LELHA, siempre en el brazo dominante de los pacientes. Se efectuaron tres mediciones en consulta separadas al menos 3 min. También se registró su peso y talla con el paciente descalzo y ropa ligera. Se midió el perímetro de cintura y se consignaron los datos analíticos, además de un electrocardiograma. Resultados La proporción de fumadores fue del 9,3%. Presentaban historia de enfermedad cardiovascular previa 21 (14%) sujetos, que fue negativa en 115 (76,7%). El índice de masa corporal (IMC) fue menor de 25 en el 13,3% de los sujetos, entre 25 y 30 en el 42,7% y mayor de 30 en el 42,7%. La presión arterial (PA) en diabéticos estaba controlada (PA ≤ 130/80 mmHg) en 33 (22%) sujetos. La glucohemoglobina (HbA1c) indicaba un control aceptable de la diabetes (HbA1c < 7) en el 42% de los pacientes. Respecto al grado de control general, 12 (8%) sujetos presentaban un control óptimo (PA < 130/80 mmHg + glucemia < 110 mg/dl + LDL < 100 mg/dl + IMC < 25). El 56% (84 individuos) cumplía criterios de síndrome metabólico. El aclaramiento de creatinina fue mayor de 70 ml/min en el 59,7% de los pacientes (90 sujetos). Los principales resultados se presentan en la tabla 1. TABLA 1 Principales resultados del estudio View Within Article Discusión y conclusiones Los resultados muestran el escaso grado de control logrado en nuestros pacientes diabéticos e hipertensos. También comprobamos que son pacientes con numerosos factores de riesgo añadidos y alto riesgo cardiovascular. Para controlar a estos pacientes, en ocasiones, modestos descensos de peso (4-8 kg) pueden mejorar tanto la HTA como el control glucémico y la dislipemia. Estos objetivos se consiguen con la prescripción de una dieta moderadamente hipocalórica, con modificación del comportamiento alimentario habitual y con la práctica de una actividad física adecuada (ejercicio aeróbico moderado 3- 4 veces por semana)4-6. En resumen, se puede considerar que el riesgo cardiovascular de los hipertensos diabéticos es alto. El grado de control de sus factores de riesgo es hasta ahora escaso. Será preciso emprender medidas correctoras para cambiar el panorama, y concienciar a los médicos sobre la importancia que adquiere el control adecuado de estos pacientes.
    Atención Primaria 01/2008; 40(1):43. DOI:10.1157/13114325 · 0.89 Impact Factor
  • Atención Primaria 01/2008; 39(12):675. · 0.89 Impact Factor
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    ABSTRACT: Objetivos Analizar la observancia terapéutica y el grado de control de la presión arterial en inmigrantes hipertensos. Estudiar el efecto de una intervención mínima para mejorar estos parámetros. Diseño Estudio de intervención no controlado. Emplazamiento Zona básica de salud de la periferia de Murcia. Participantes Se incluyó a 150 pacientes inmigrantes de 40 a 75 años, hipertensos esenciales de más de un año de evolución, en tratamiento farmacológico. A todos ellos se les aplicó una intervención mínima para mejorar la observancia terapéutica. Se excluyó a los que no poseían un manejo adecuado del castellano tanto oral como escrito. Intervenciones En la visita inicial, se medía la observancia terapéutica y la presión arterial, y se realizaba la intervención mínima, consistente en dar la posología por escrito en una plantilla diseñada para el estudio y comprobar que el paciente la había entendido, ya que se le pedía que explicase al médico lo que se indicaba en la plantilla. El idioma en que se expresaba la plantilla era el castellano. A los 4 meses, se volvía a medir la observancia terapéutica y el control o no de la presión arterial. Resultados En la visita inicial la observancia terapéutica fue muy buena en el 9,33% (n = 14) de los sujetos, y buena en el 12% (n = 18) (tabla 1). La presión arterial era < 140/90 mmHg en el 17,33% (n = 26) de los pacientes. En la visita final (a los 4 meses) la observancia terapéutica había mejorado significativamente, que fue muy buena en el 20% (n = 30) de los hipertensos, y buena, en el 32% (n = 48) (tabla 1). En la visita final la presión arterial era < 140/90 mmHg en el 33,33% (n = 50) de los pacientes. El análisis comparativo entre el grupo de inmigrantes magrebíes y sudamericanos no mostró diferencias en ninguna de las fases del estudio. Discusión y conclusions Los determinantes de salud de los inmigrantes se derivan de la dificultad de conseguir un traba TABLA 1 Valores de observancia y presión arterial antes y después de la intervención mínima View Within Article Los resultados de este estudio ponen de manifiesto que se debe diseñar algunas estrategias para lograr una mejor atención sanitaria al paciente inmigrante tanto desde la Administración como de los profesionales que trabajan en atención primaria. Algunas propuestas podrían ser la formación de profesionales sanitarios y no sanitarios para fomentar el conocimiento de aspectos relacionados con la inmigración (comunicación intercultural, enfermedades importadas, respeto a los valores de otras culturas, etc.). También sería de gran utilidad elaborar guías y protocolos de atención específicos para el paciente inmigrante. Los protocolos y guías de práctica clínica son elementos imprescindibles para garantizar la calidad de la asistencia sanitaria. La disponibilidad de hojas de anamnesis, órdenes de tratamiento y consejos de educación para la salud en varios idiomas mejoraría la calidad de la atención prestada1-6. En conclusión, la observancia terapéutica y el control de la presión arterial de nuestros pacientes hipertensos inmigrantes son muy deficientes, por lo que se precisan medidas específicas para mejorar la salud de estos pacientes.
    Atención Primaria 12/2007; 39(12):675-675. DOI:10.1157/13113963 · 0.89 Impact Factor