M P Agarwal

University College of Medical Sciences, Delhi, NCT, India

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Publications (15)15.3 Total impact

  • Atherosclerosis Supplements 05/2008; 9(1):98-98. · 4.33 Impact Factor
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    ABSTRACT: The bark powder of Terminalia arjuna, an indigenous plant has been found to have antianginal, decongestive and hypolipidemic effect. We planned a study to evaluate the role of T. arjuna in ischemic mitral regurgitation (IMR) following acute myocardial infarction (AMI). 40 patients with fresh AMI showing IMR were randomly divided into 2 groups of 20 each. They were given placebo or 500 mg of T. arjuna in addition to anti-ischemic treatment. After 1 and 3 months of follow up, patients receiving adjuvant T. arjuna showed significant decrease in IMR, improvement in E/A ratio and considerable reduction in anginal frequency.
    International Journal of Cardiology 01/2005; 100(3):507-508. · 6.18 Impact Factor
  • S Dwivedi, S Singh, M P Agarwal, S Rajpal, A Aneja
    The Journal of the Association of Physicians of India 05/2004; 52:340-2.
  • Tropical Doctor 05/2003; 33(2):110-1. · 0.61 Impact Factor
  • S Dwivedi, M P Agarwal, P Gangwal
    Indian Journal of Medical Sciences 11/2002; 56(10):535. · 1.67 Impact Factor
  • S Dwivedi, G Singh, M P Agarwal
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    ABSTRACT: To study clinical profile of hypertension in elderly subjects. Two hundred and five consecutive subjects aged 60 years and above reporting to preventive cardiology clinic with cardiovascular disorders were studied. One hundred fifty six subjects (76.09%) were found to have essential hypertension (HTN). Newly detected hypertensives were classified as per JNC-VI classification. Detailed clinical examination and laboratory investigations were carried out to find evidence of associated ailments with HTN. Most of the patients belonged to 60-70 years age group. Mean age was 67.36 +/- 6.23 years (range 60 to 90 years) and male to female ratio was 1.44:1. Out of hypertensives 99 (63.46%) had HTN for long period, while 28 (17.94%), 17 (10.89%) and 12 (7.67%) belonged to mild, moderate and severe HTN categories, respectively. Out of newly detected hypertensives 14 (24.56%) were having isolated systolic HTN. Associated clinical conditions in hypertensives were coronary artery disease (CAD), non-insulin dependent diabetes mellitus (NIDDM), cerebrovascular disease (CVD), left ventricular hypertrophy (LVH) and chronic obstructive pulmonary disease (COPD) in 69 (57.05%), 49 (31.41%), 37 (23.71%), 20 (12.80%) and 10 (6.4%) subjects, respectively. HTN alone was found in 31 (19.87%) subjects only. Since most of these patients had other concomitant illnesses such as CAD. NIDDM etc. therapy was initiated accordingly. Four (20%) patients with LVH died within short period of 1 to 12 weeks. HTN is the commonest cardiovascular disorder in elderly subjects. CAD, NIDDM and CVD are commonly associated clinical conditions. Patients with associated LVH have very high short term mortality.
    The Journal of the Association of Physicians of India 12/2000; 48(11):1047-9.
  • M Jain, M P Agarwal, J S Wasir, S Dwivedi
    The Journal of the Association of Physicians of India 01/2000; 47(12):1205-6.
  • S Dwivedi, M P Agarwal, R Jauhari
    Tropical Doctor 08/1998; 28(3):180. · 0.61 Impact Factor
  • S Dwivedi, A K Jain, M P Agarwal, A Aneja
    Tropical Doctor 05/1998; 28(2):117. · 0.61 Impact Factor
  • Tropical Doctor 05/1995; 25(2):82-3. · 0.61 Impact Factor
  • S Dwivedi, M P Agarwal
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    ABSTRACT: The effect of bark powder of Terminalia arjuna, an indigenous drug, on anginal frequency, blood pressure, body mass index, blood sugar, cholesterol and HDL-cholesterol was studied in 15 stable (Group A) and 5 unstable (Group B) angina patients before and 3 months after T. arjuna therapy. Tread mill test (TMT) and echocardiographic left ventricular ejection fraction was evaluated in some cases. There was 50% reduction in anginal episodes in Group A cases (P < 0.01). TMT performance improved from moderate to mild changes in 5 patients and one with mild changes became negative for ischemia. The time to the onset of angina and appearance of ST-T changes on TMT after T. arjuna was delayed significantly. However, in patients with unstable angina there was an insignificant reduction in anginal frequency. These patients also needed diltiazem, B-blockers and nitroglycerine in addition to T. arjuna. The drug lowered systolic blood pressure and body mass index to a significant level (p < 0.05) and increased HDL-cholesterol only slightly along with marginal improvement in left ventricular ejection fraction in stable angina patients. There were no deleterious effects on liver or kidney functions. Our results suggest that monotherapy with T. arjuna is fairly effective in patients with symptoms of stable angina pectoris. However, it has a limited role in unstable angina.
    The Journal of the Association of Physicians of India 04/1994; 42(4):287-9.
  • S Dwivedi, M P Agarwal
    The Journal of the Association of Physicians of India 03/1994; 42(2):176.
  • D D Bhadoria, M P Agarwal, S Dwivedi
    Indian Journal of Pathology and Microbiology 05/1993; 36(2):190-1. · 0.68 Impact Factor
  • S Dwivedi, M P Agarwal, C P Suthar, G Dwivedi
    Indian heart journal 56(3):258-9.
  • S. Dwivedi, G. Singh, M. P. Agarwal
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    ABSTRACT: The increase in longevity due to control of communicable diseases and improved nutrition and health care facilities has led to surge in both elderly population (>60 years) and cardiovascular ailments worldwide including India. Cardiovascular and associated medical illnesses are major ailments responsible for considerable morbidity and mortality among elderly subjects. The present article briefly highlights common cardiovascular disorders including principal risk factors, associated medical ailments and their preventive and treatment strategies. Common cardiovascular disorders in this population include hypertension (HTN), coronary artery disease (CAD) including myocardial infarction, angina pectoris, congestive heart failure, arrhythmias, ischaemic cardiomyopathy and cerebrovascular diseases (CVD). HTN and smoking are the principal risk factors both for CAD as well as CVD. Left ventricular hypertrophy (LVH) is a major predictor for sudden cardiac death in elderly people. Important associated medical conditions in conjunction with cardiovascular disorders include diabetes, chronic obstructive pulmonary disease (COPD), benign prostatic hypertrophy (BPH), cataract, pneumonias and bronchial asthma. Adverse factors which influence mortality include-age > 68 years, extensive infarction cardiogenic shock, LVH, arrhythmias, intracerebral haemorrhage, cerebral infarction and respiratory failure.
    Social change 29(1-2):158-170.