Ronald E Delanois

Sinai Hospital, Baltimore, Maryland, United States

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Publications (65)147.35 Total impact

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    ABSTRACT: Purpose: Postoperative dislocation is one of the most common complications following total hip arthroplasty (THA), and dual mobility articulations have been designed to provide greater hip stability. However, there are few studies that have assessed outcomes of these designs in revision THAs. Our purpose was to evaluate differences in dislocation rates, aseptic survivorship, and patient outcomes between dual mobility articulations and conventional arthroplasties in the revision setting. Methods: Patients who underwent revision THA with dual mobility articulations (n = 60) were matched (1:2) to patients who had conventional single articulation prostheses (n = 120). They were matched for body mass index, age, gender, and Paprosky acetabular defect classification, and were followed up for a mean of 30 months (range, 18 to 52 months). The outcomes were evaluated preoperatively and at final follow-up using Harris Hip Scores, the University of California Los Angeles activity scale, and the Short Form-36 questionnaires. Results: The dual mobility group had lower dislocation (1.7% (1 out of 60) versus 5.8% (7 out of 120)) and aseptic loosening rates (1.7% (1 out of 60) versus 4.2% (5 out of 120)) compared to the control group. There were no significant differences in functional outcomes, activity level, or overall physical and mental health status between the 2 cohorts. Conclusions: When used in the revision setting, dual mobility bearings had fewer dislocations. We believe that these designs may lead to clinically significant improvements in complications while also improving patient reported and functional outcomes, but larger cohort studies are necessary for evaluation.
    Hip international: the journal of clinical and experimental research on hip pathology and therapy 09/2015; DOI:10.5301/hipint.5000295 · 0.76 Impact Factor
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    ABSTRACT: Due to the high number of total hip arthroplasties (THA) revised due to instability, the use of large femoral heads to reduce instability is justifiable. It is critical to determine whether or not large femoral heads used in conjunction with thin polyethylene liners lead to increased wear rates, which can lead to osteolysis. Therefore, by using validated wear-analysis software, we evaluated linear wear rates in a consecutive cohort of patients who underwent primary THA with thin polyethylene liners. All patients were selected from a consecutive, prospectively collected database of 241 THAs performed at a single institution by two fellowship-trained joint-reconstruction surgeons between July 2007 and June 2011. These patients were 1:1 matched to a cohort of patients who had conventional-thickness polyethylene liners. No significant differences were observed between linear wear rates of thin or conventional-thickness liners. The Kaplan-Meier survivorship for both cohorts was 100 %, and no cases of polyethylene fracture were observed in either cohort. Our results suggest that according to a mean follow-up of 4 years, the use of thin liners in THA is promising. Longer follow-up is required to assess whether these outcomes are observed later.
    International Orthopaedics 07/2015; DOI:10.1007/s00264-015-2841-4 · 2.11 Impact Factor
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    ABSTRACT: Over the past three decades, non-vascularized bone grafts have been demonstrated to be viable treatments for pre- and early post-collapse osteonecrosis of the femoral head; however, there are limited reviews on this topic. Therefore, the purposes of this review are to (1) provide a summary of the different surgical techniques and their respective clinical outcomes and (2) evaluate new adjunct therapies. Originally, non-vascularized bone grafting was performed using the Phemister technique with varying results. More recently, newer techniques such as the lightbulb and trapdoor are used to place non-vascularized bone grafts with excellent results. The addition of various biological agents has demonstrated positive results; however, further studies are needed to confirm the best appropriate indications and to elucidate long-term results.
    Current Reviews in Musculoskeletal Medicine 05/2015; 8(3). DOI:10.1007/s12178-015-9282-y
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    ABSTRACT: The routine use of highly cross-linked ultra-high molecular weight polyethylene (UHMWPE) has remained controversial secondary to the possibility of decreased material properties when compared to conventional UHMWPE. The aim of the present study was to evaluate if thin, sequentially-irradiated, and annealed highly cross-linked UHMWPE tibial inserts would have improved wear properties, while maintaining mechanical integrity, compared to conventional UHMWPE during biomechanical testing under aligned and malaligned conditions. Polyethylene inserts (4.27 and 6.27mm) manufactured from GUR 1020-UHMWPE were cyclically loaded to analyze for wear. All wear scars were visually examined after loading using scanning electron microscopy (SEM). Volume loss was plotted versus cycle count with linear regression analysis yielding wear rates. There was no statistical difference in wear between both thicknesses for all testing conditions. During aligned condition testing, the volumetric wear rate for sequentially-irradiated and annealed polyethylene thicknesses of 4.27 and 6.27mm was 4.0 and 4.4mm3/million cycles; and during malaligned conditions, it was 13.9 and 15.1mm3/million cycles. For conventional polyethylene during aligned conditions, the volumetric wear rate was 33.0 and 22.8mm3/million cycles; and during malaligned conditions it was 50.0 and 50.8mm3/million cycles. By SEM evaluation, condylar wear surfaces for conventional and sequentially-irradiated and annealed polyethylene displayed surface ripples typical of adhesive wear. There were no observed visible differences between the wear scars for conventional compared to sequentially-irradiated and annealed polyethylene with no evidence of fatigue failure. This study demonstrated no differences between polyethylenes with thicknesses of 4.27 and 6.27mm. This strengthens the conclusion that sequentially-irradiated and annealed highly cross-linked UHMWPE can be utilized in total knee arthroplasty. The successful wear properties of 4.27mm liners could mean that smaller tibial resections leading to bone stock preservation could be utilized in patients undergoing total knee arthroplasty, although further in-vivo studies are needed.
    Surgical technology international 05/2015; 26:329-35.
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    ABSTRACT: Unfavorable outcomes from trunnion fretting and corrosion damage have been reported in the literature, gross failures of tapers in primary total hip arthroplasties have been less frequently reported. We report on 5 patients, who presented with gross trunnion failures of modular metal-on-polyethylene or ceramic-on-polyethylene bearings from 5 implant manufacturers, all necessitating revision surgery. None of these patients had an antecedent history of trauma, and the majority presented with pain or instability. No common factor was identified that may be predictive of these type of failures. Since there were 5 different stem designs, this suggests that it may be a rare generic phenomenon occurring with multiple designs. Currently, further investigations are necessary, including retrieval analysis, to identify risk factors that may predispose to such failures. Copyright © 2014 Elsevier Inc. All rights reserved.
    The Journal of Arthroplasty 11/2014; 30(4). DOI:10.1016/j.arth.2014.11.023 · 2.67 Impact Factor
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    ABSTRACT: The effect of acetabular component positioning on the wear rates of metal-on-polyethylene articulations has not been extensively studied. Placement of acetabular cups at abduction angles of more than 40° has been noted as a possible reason for early failure caused by increased wear. We conducted a study to evaluate the effects of different acetabular cup abduction angles on polyethylene wear rate, wear area, contact pressure, and contact area. Our in vitro study used a hip joint simulator and finite element analysis to assess the effects of cup orientation at 4 angles (0°, 40°, 50°, 70°) on wear and contact properties. Polyethylene bearings with 28-mm cobalt-chrome femoral heads were cycled in an environment mimicking in vivo joint fluid to determine the volumetric wear rate after 10 million cycles. Contact pressure and contact area for each cup abduction angle were assessed using finite element analysis. Results were correlated with cup abduction angles to determine if there were any differences among the 4 groups. The inverse relationship between volumetric wear rate and acetabular cup inclination angle demonstrated less wear with steeper cup angles. The largest abduction angle (70°) had the lowest contact area, largest contact pressure, and smallest head coverage. Conversely, the smallest abduction angle (0°) had the most wear and most head coverage. Polyethylene wear after total hip arthroplasty is a major cause of osteolysis and aseptic loosening, which may lead to premature implant failure. Several studies have found that high wear rates for cups oriented at steep angles contributed to their failure. Our data demonstrated that larger cup abduction angles were associated with lower, not higher, wear. However, this potentially "protective" effect is likely counteracted by other complications of steep cup angles, including impingement, instability, and edge loading. These factors may be more relevant in explaining why implants fail at a higher rate if cups are oriented at more than 40° of abduction.
    American journal of orthopedics (Belle Mead, N.J.) 10/2014; 43(10):466-71.
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    ABSTRACT: Manipulation under anesthesia has been reported to improve range of motion when other rehabilitative efforts fail to obtain adequate motion after total knee arthroplasty. The purpose of this study was to evaluate the effects of the timing of the manipulation on knee range of motion and clinical outcomes.
    The Journal of Bone and Joint Surgery 08/2014; 96(16):1349-57. DOI:10.2106/JBJS.M.00899 · 5.28 Impact Factor
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    Ronald E Delanois · Michael A Mont ·

    The Journal of Bone and Joint Surgery 11/2013; 95(22):e1791-2. DOI:10.2106/JBJS.M.01086 · 5.28 Impact Factor
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    ABSTRACT: Symptomatic osteonecrosis of the joint is a frequent debilitating complication in patients who have been infected with the human immunodeficiency virus (HIV). In earlier reports, outcomes of primary total joint arthroplasty in such patients have been poor due to early failures, high infection rates, and increased complication rates. We report on the clinical and radiographic outcomes of primary total hip arthroplasty (THA) in nonhemophilic, HIV-infected patients as compared with the outcomes in a cohort of osteonecrosis patients who did not have this disease. Thirty-four HIV-infected patients (forty-four hips) who underwent primary THA for the treatment of osteonecrosis during the period of 2001 through 2008 were compared with a control cohort of seventy patients (seventy-eight hips) who also underwent THA for the treatment of osteonecrosis but did not have HIV or other high-risk factors for revision. The patients in the HIV study group (eleven women and twenty-three men) had a mean age of forty-eight years (range, thirty-four to eighty years) and were followed for a mean of seven years (range, four to eleven years). Evaluated outcomes included implant survivorship, Harris hip score, infection rate, activity score, postoperative Short-Form 36 (SF-36) health survey score, and radiographic outcome. Kaplan-Meier survival analysis demonstrated no significant difference in aseptic implant survivorship between the HIV and comparison cohorts at the five-year (100% vs. 98%, respectively) and ten-year (95% vs. 96.5%, respectively) follow-up times. In addition, at the time of final follow-up, the mean postoperative Harris hip scores (85 points in the HIV group vs. 87 points in the comparison group), activity scores (5.7 points in the HIV group vs. 6.1 points in the comparison group), and SF-36 physical (43 points in the HIV group versus 46 points in the comparison group) and mental component summary scores (54 points in the HIV group versus 57 points in the comparison group) were statistically similar between the two cohorts. There were two late infections in the HIV cohort as compared with none in the comparison cohort. Our results demonstrated excellent implant survivorship, clinical and radiographic outcomes, and minimal complications at the time of midterm follow-up in the HIV-infected patient group. We believe that the outcomes associated with primary THA are improving in this patient population as a result of better medical management; however, late infections are potential complications. Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.
    The Journal of Bone and Joint Surgery 10/2013; 95(20):1845-50. DOI:10.2106/JBJS.L.01583 · 5.28 Impact Factor
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    ABSTRACT: The purpose of this study was to determine the clinical outcomes of manipulation under anesthesia (MUA) in a cohort who had developed knee stiffness following total knee arthroplasty (TKA). One-hundred and forty-five TKAs in 134 patients who had undergone MUA were compared to the remaining 1973 TKAs in 1671 patients who did not develop this condition. At a mean follow-up of 51months (range, 24 to 85months), the mean gains in flexion in the MUA cohort were 33° (range, 5° to 65°). The final range-of-motion in the MUA cohort was lower than the comparison cohort (114° versus 125°) however, this would meet the required flexion for activities of daily living. There were no differences in the Knee Society objective and functional scores between the two cohorts. It is encouraging that MUA cohort outcomes were comparable to outcomes of patients who did not develop knee stiffness.
    The Journal of arthroplasty 08/2013; 29(3). DOI:10.1016/j.arth.2013.07.046 · 2.67 Impact Factor
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    ABSTRACT: Dislocation remains the leading cause of revision THA. One approach to decreasing prosthetic dislocation risk has been the use of larger femoral head component sizes. The upper limit of head size in metal-on-polyethylene hip arthroplasty has historically been limited because of concerns about increased wear on thin polyethylene components. It is not known to what degree this concern should apply to more wear-resistant polyethylene components. We therefore determined (1) in vitro wear rates of polyethylene liners of varying thicknesses, (2) whether there were differences in the microscopic wear characteristics as a function of polyethylene thickness, and (3) whether thin polyethylene components resulted in early catastrophic failures. We used a hip wear simulator to compare the wear performance of 12 highly crosslinked polyethylene acetabular inserts. The internal diameter of all components was 36 mm, and there were three samples tested of each thickness (1.9, 3.9, 5.9, or 7.9 mm). Testing was conducted for 2.4 million cycles. Gravimetric mass loss was converted to volumetric loss, which was subsequently converted to theoretical linear penetration rates. Wear rates decreased with increasing polyethylene thickness. Mean ± SD wear rates for the 1.9-, 3.9-, 5.9-, and 7.9-mm groups were 5.0 ± 0.5, 3.2 ± 0.3, 2.5 ± 1.1, and 2.2 ± 1.3 mm(3)/million cycles, respectively (p < 0.016). Calculated penetration rates were 0.015, 0.012, 0.011, and 0.010 mm/million cycles, respectively (p < 0.016). There were no catastrophic failures in any group. Thinner polyethylene components demonstrated higher wear rates, although even the highest wear rate observed in the thinnest polyethylene specimen was lower than that commonly reported for noncrosslinked polyethylene components. While encouraging, these findings should be validated in vivo before clinical recommendations can be made.
    Clinical Orthopaedics and Related Research 07/2013; 472(2). DOI:10.1007/s11999-013-3153-x · 2.77 Impact Factor
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    ABSTRACT: The purpose of this study was to compare the outcomes of cementless primary total hip arthroplasty (THA) in sickle cell patients compared to the remaining cohort of osteonecrosis patients who did not have this disease. Thirty-two sickle cell patients (42 hips) who had a mean age of 37years and mean follow-up of 7.5years (range, 5-11years) were compared to 87 non-sickle cell osteonecrosis patients (102 hips) who had mean age of 43years and mean follow-up of 7years (range, 3-10.5years). Outcomes evaluated included implant survivorship, Harris hip scores, complication rates, radiographic outcomes, and Short Form-(SF-36) health questionnaire. There were no significant differences in aseptic implant survivorship (95 vs. 97%), Harris hip scores (87 vs. 88 points), SF-36 score, or radiographic findings between the two patient cohorts. In light of these findings, we believe that the outcomes of THA improved in sickle cell patients with optimized medical management and the use of cementless prosthetic devices.
    The Journal of arthroplasty 05/2013; 28(9). DOI:10.1016/j.arth.2013.03.017 · 2.67 Impact Factor
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    ABSTRACT: Nineteen patients (nineteen hips) who had undergone revision total hip arthroplasties using a proximally-coated primary cementless stem were evaluated to determine if a subset of revision arthroplasty patients could be identified where the use of this stem would be appropriate. Of these 19 revisions, 15 were performed for the second stage treatment of infection. The femoral bone deficiency was classified as Paprosky Type I in 6 hips and Type II in 13 hips. At a mean follow-up of 49months, aseptic stem survivorship was 95% with one revision due to aseptic stem failure. The mean Harris hip scores had improved from a mean of 44 points pre-operatively to 89 points post-operatively. Intra-operatively, there was one complication which included a peri-prosthetic fracture distal to the stem which was treated with an allograft strut with cerclage wires. The authors believe that in type I or II femoral defects, the use of this specific cementless stem may be beneficial in the setting of a revision total hip arthroplasty.
    The Journal of arthroplasty 05/2013; 29(1). DOI:10.1016/j.arth.2013.04.025 · 2.67 Impact Factor
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    ABSTRACT: The purpose of this study was to assess the clinical and radiographic outcomes of total hip arthroplasty (THA) in patients who had osteonecrosis to see if prior hip preserving surgery affected outcomes. Implant survivorship, Harris hip scores, and radiographic outcomes were compared between 87 patients (92 hips) who had undergone prior hip preserving procedures and 105 patients (121 hips) who had only undergone THA. Patients were also sub-stratified into low- and high-risk groups for osteonecrosis. At a mean follow-up of 75 months, there were no significant differences in survivorship, clinical, and radiographic outcomes among the cohorts. Higher revision rates were associated with patients who were in the high-risk group. The authors believe that hip joint preserving procedures may not adversely affect the outcomes of later THA in patients with osteonecrosis.
    The Journal of arthroplasty 05/2013; 29(1). DOI:10.1016/j.arth.2013.04.028 · 2.67 Impact Factor
  • D Alex Stroh · Kimona Issa · Aaron J Johnson · Ronald E Delanois · Michael A Mont ·
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    ABSTRACT: The purpose of this study was to compare the dislocation rates, functional outcomes, and radiographic results between large- and small-diameter femoral head components. A total of 225 patients (248-hips) who received total hip arthroplasties with large-diameter components (36mm or greater) were compared to 501 patients (559-hips) who received smaller diameter components (less than 36mm). Rates of dislocation and revision, Harris hip score, radiographic findings, and complications were compared between the groups. At a mean follow-up of approximately 5years, a significantly higher rate of dislocation was noted in the small-diameter group (10 of 559) compared to the large-diameter group (0 of 248). The overall implant survivorship, mean Harris hip scores, complication rates, and radiographic outcomes were similar for the two groups. The authors believe that large-diameter components significantly reduced the risk of dislocation in susceptible patients, while preserving good to excellent functional outcomes.
    The Journal of arthroplasty 04/2013; 28(8). DOI:10.1016/j.arth.2012.11.017 · 2.67 Impact Factor
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    ABSTRACT: Background Surgeons are often trying to decreased reinfection rates following two-stage reimplantation arthroplasty, which range from 3.2% to 13% because multiple staged revision procedures for infection can be costly and have high morbidity. We therefore asked: (1) Did the use of postoperative oral antibiotics reduce reinfection rates after 2-staged revision of THA? And (2) how did this compare with the infection rate after aseptic revision procedures? Methods We identified all patients who underwent two-stage revision THA for a periprosthetic deep hip infection and found 66 patients (67 hips) who had a minimum 24 months’ followup. Twenty-two of the 66 procedures (33%) were followed by a minimum of 14 days of postoperative oral antibiotics (mean, 36 days; range, 14 days to lifelong), while 44 were prescribed only immediate parenteral postoperative antibiotic therapy (mean, 1.3 days; range, 1–3 days). We then identified 407 patients (410 hips) who underwent aseptic revision hip arthroplasty and evaluated the infection rate in these patients for comparison; these patients were treated with 24 hours of postoperative parenteral antibiotics. The authors used previously described creteria to establish the presence of infection. Results There were no reinfections in the group receiving oral postoperative antibiotics compared to six reinfections (13.6%) in the 44 patients not receiving oral antibiotics. We observed infection in 2 of the 410 hips (0.5%) revised for aseptic reasons. Conclusions We believe that our findings warrant further investigation for using postoperative oral antibiotics after reimplantation for periprosthetic infection in an effort to decrease the likelihood and risks associated with additional revision arthroplasty procedures.
    BMC Musculoskeletal Disorders 04/2013; 14(1):123. DOI:10.1186/1471-2474-14-123 · 1.72 Impact Factor
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    Qais Naziri · Kimona Issa · Robert Pivec · Steven F Harwin · Ronald E Delanois · Michael A Mont ·
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    ABSTRACT: Cementless acetabular cups for primary total hip arthroplasty have had excellent results, with failure rates typically less than 5% at up to 10-year follow-up. Tritanium is a 3-dimensional metal interface that has been used for porous biological fixation. The purpose of this study was to review the clinical and radiographic results of the use of Tritanium cups (Stryker Orthopaedics, Mahwah, New Jersey) for primary total hip arthroplasty. Two hundred eighty-eight total hip arthroplasties performed using a porous titanium acetabular cup in 252 patients between 2008 and 2010 were reviewed. One hundred thirty-three men and 119 women with a mean age of 58 years (range, 18-88 years) were included. Mean follow-up was 36 months (range, 24-56 months). Outcomes evaluated were implant survivorship, Harris Hip Score, complications, and radiographic outcomes. At final follow-up, no cup failures had occurred. Mean Harris Hip Score improved from 53 points (range, 33-82 points) preoperatively to 91 points (range, 64-100 points) postoperatively. One complication occurred; a 64-year-old woman with recurrent postoperative effusions underwent hip exploration and required abductor mechanism repair. On radiologic evaluation, no signs existed of progressive radiolucencies or changes in cup position. The survivorship of the Tritanium cup and the low complication rate is comparable with previous studies using other porous-metal prostheses. Longer follow-up study is needed and assessment of the results of using this implant in the revision setting is important.
    Orthopedics 04/2013; 36(4):e390-e394. DOI:10.3928/01477447-20130327-10 · 0.96 Impact Factor
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    ABSTRACT: The purpose of this study was to compare the clinical and radiographic outcomes of primary total knee arthroplasty (TKA) in obese and nonobese patients. A total of 210 knees in 174 obese patients who had a mean body mass index (BMI) of 34 kg/m2 (range, 30 to 39.9 kg/m2) and who had undergone a primary TKA between 2006 and 2010 were reviewed. There were 115 women and 59 men who had a mean age of 62 years (range, 36 to 84 years) and a mean follow-up of 57 months (range, 24 to 82 months). These patients were compared with a group of nonobese patients who had a BMI of less than 30 kg/m2 (range, 19 to 29.9 kg/m2). The evaluated outcomes included implant survivorship, Knee Society objective and functional scores, complication rates, radiographic outcomes, University of California Los Angeles (UCLA) activity score, and the length of hospital stay between obese and nonobese patients. There were no significant differences in the overall septic and aseptic implant survivorship (98.8 vs. 98.6%) and mean postoperative Knee Society objective and function scores (90 and 87 points vs. 91 and 89 points), respectively. Obese patients had significantly higher complication rates (10.5 vs. 3.8%) and had achieved a significantly lower mean postoperative UCLA activity score (5 vs. 6 points). However, there were no differences in the length of hospital stay for the two cohorts. Although the authors encourage all patients to lose weight as much as possible prior to their TKA, it is encouraging that obese patients had achieved excellent clinical outcomes at early to mid-term follow-up.
    The journal of knee surgery 03/2013; 26(2). DOI:10.1055/s-0033-1341408 · 1.44 Impact Factor
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    ABSTRACT: This report includes a series of eight cases in which a dual-mobility prosthesis was utilized for difficult acetabular reconstructive hip arthroplasty cases. Most of the patients described had multiple reasons for hip instability (including prior multiple surgeries, abductor muscle insufficiency, prior infection). All patients were successfully managed with this device and this report includes a brief description of its use compared with other surgical reconstruction methods for instability.
    Surgical technology international 12/2012; XXI:234-240.
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    ABSTRACT: The purpose of this study was to compare the clinical outcomes of total knee arthroplasty in patients who reported a history of tobacco use with those who were nonsmokers. Between 2006 and 2009, there were 131 total knee arthroplasties performed in patients who were smokers and 490 in patients who did not smoke. At a mean follow-up of 47 months (range, 24-79 months), the patients who were smokers had a statistically decreased overall survivorship of 90% (13 revisions) compared with 99% (5 revisions) in the nonsmokers. Surgical complication rates were not significantly different between the 2 groups; however, there was a significant difference in medical complications. Total knee arthroplasty in smokers has a higher risk of negative clinical outcomes compared with nonsmokers.
    The Journal of arthroplasty 05/2012; 27(9):1690-1695.e1. DOI:10.1016/j.arth.2012.03.057 · 2.67 Impact Factor

Publication Stats

1k Citations
147.35 Total Impact Points


  • 2006-2014
    • Sinai Hospital
      Baltimore, Maryland, United States
  • 2009
    • Howard University Hospital
      Washington, Washington, D.C., United States
  • 2002
    • Naval Medical Center Portsmouth
      Portsmouth, Virginia, United States
  • 1998
    • Good Samaritan Hospital
      Cincinnati, Ohio, United States