M J Kim

Publications (849)1981.48 Total impact

• Article: Evidence for B_s^0 -> Lambda_c^+ Lambda-bar pi^-

  Belle Collaboration, E. Solovieva, R. Chistov, I. Adachi, D. M. Asner, T. Aushev, A. M. Bakich, A. Bala, V. Bhardwaj, B. Bhuyan, [......], Y. Watanabe, K. M. Williams, E. Won, B. D. Yabsley, Y. Yamashita, S. Yashchenko, Y. Yook, Z. P. Zhang, V. Zhilich, A. Zupanc
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  ABSTRACT: Using 121.4 fb^{-1} of data collected with the Belle detector at the Y(5S) resonance at the KEKB asymmetric-energy e^+e^- collider, we report evidence for the B_s^0 -> Lambda_c^+ Lambda-bar pi^- decay mode with a measured branching fraction (3.6 +- 1.1[stat.] {+0.3 -0.5}[syst.] +- 0.9[Lambda_c^+] +- 0.7[N_{Bs}]) * 10^{-4} and a significance of 4.4 standard deviations. This is the first evidence for a baryonic B_s^0 decay.
  04/2013;
• Article: Evidence for the decay B0 --> K+K-pi0

  The Belle Collaboration, V. Gaur, G. B. Mohanty, T. Aziz, I. Adachi, H. Aihara, D. M. Asner, V. Aulchenko, T. Aushev, A. M. Bakich, [......], M. Watanabe, Y. Watanabe, K. M. Williams, E. Won, B. D. Yabsley, Y. Yamashita, S. Yashchenko, Y. Yusa, V. Zhilich, A. Zupanc
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  ABSTRACT: We report a search for charmless hadronic decays of neutral B mesons to the final state K+K-pi0. The results are based on a 711 fb^-1 data sample that contains 772x10^6 BB-bar pairs, and was collected at the Y(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. We find the first evidence for this decay with a significance of 3.5 standard deviations and measure its branching fraction as BF(B0 --> K+K-pi0) = [2.17 +/- 0.60(stat) +/- 0.24 (syst)]x10^-6.
  04/2013;
• Article: Exclusion of exotic top-like quarks with -4/3 electric charge using jet-charge tagging in single-lepton ttbar events at CDF

  CDF Collaboration, T. Aaltonen, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, J. A. Appel, T. Arisawa, [......], K. Yi, J. Yoh, K. Yorita, T. Yoshida, G. B. Yu, I. Yu, A. M. Zanetti, Y. Zeng, C. Zhou, S. Zucchelli
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  ABSTRACT: We report on a measurement of the top-quark electric charge in ttbar events in which one W boson originating from the top-quark pair decays into leptons and the other into hadrons. The event sample was collected by the CDF II detector in sqrt(s)=1.96 TeV proton-antiproton collisions and corresponds to 5.6 fb^(-1). We find the data to be consistent with the standard model and exclude the existence of an exotic quark with -4/3 electric charge and mass of the conventional top quark at the 99% confidence level.
  04/2013;
• Article: Evidence of a new narrow resonance decaying to $\chi_{c1}\gamma$ in $B \to \chi_{c1} \gamma K$

  Belle Collaboration, V. Bhardwaj, K. Miyabayashi, I. Adachi, H. Aihara, D. M. Asner, V. Aulchenko, T. Aushev, T. Aziz, A. M. Bakich, [......], J. Yamaoka, Y. Yamashita, S. Yashchenko, Y. Yook, C. Z. Yuan, C. C. Zhang, Z. P. Zhang, V. Zhilich, V. Zhulanov, A. Zupanc
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  ABSTRACT: We report measurements of $B \to \chi_{c1} \gamma K$ and $\chi_{c2} \gamma K$ decays using $772 \times 10^{6}$ $B\bar{B}$ events collected at the $\Upsilon(4S)$ resonance with the Belle detector at the KEKB asymmetric-energy $e^+e^-$ collider. Evidence of a new resonance in the $\chi_{c1} \gamma$ final state is found with a statistical significance of $3.8 \sigma$. This state has a mass of $3823.1 \pm 1.8 {(stat)} \pm 0.7 {(syst)}$ MeV/$c^2$, a value that is consistent with theoretical expectations for the previously unseen $1^3 D_2$ $c\bar{c}$ meson. We find no other narrow resonance and set upper limits on the branching fractions of the $X(3872) \to \chi_{c1} \gamma$ and $\chi_{c2} \gamma$ decays.
  04/2013;
• Article: Study of $e^+ e^- \to \pi^+ \pi^- J/\psi$ and Observation of a Charged Charmonium-like State at Belle

  Belle Collaboration, Z. Q. Liu, C. P. Shen, C. Z. Yuan, I. Adachi, H. Aihara, D. M. Asner, V. Aulchenko, T. Aushev, T. Aziz, [......], B. D. Yabsley, J. Yamaoka, Y. Yamashita, S. Yashchenko, Y. Yook, Y. Yusa, C. C. Zhang, Z. P. Zhang, V. Zhilich, A. Zupanc
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  ABSTRACT: The cross section for $e^+ e^- \to \pi^+ \pi^- J/\psi$ between 3.8 GeV and 5.5 GeV is measured with a 967 fb$^{-1}$ data sample collected by the Belle detector at or near the $\Upsilon(nS)$ ($n = 1,\ 2,\ ...,\ 5$) resonances. The Y(4260) state is observed, and its resonance parameters are determined. In addition, an excess of $\pi^+ \pi^- J/\psi$ production around 4 GeV is observed. This feature can be described by a Breit-Wigner parameterization with properties that are consistent with the Y(4008) state that was previously reported by Belle. In a study of $Y(4260) \to \pi^+ \pi^- J/\psi$ decays, a structure is observed in the $M(\pi^\pm\jpsi)$ mass spectrum with $5.2\sigma$ significance, with mass $M=(3894.5\pm 6.6\pm 4.5) {\rm MeV}/c^2$ and width $\Gamma=(63\pm 24\pm 26)$ MeV/$c^{2}$, where the errors are statistical and systematic, respectively. This structure can be interpreted as a new charged charmonium-like state.
  03/2013;
• Article: Search for B -> h(*) nu nubar with the full Belle Y(4S) data sample

  O. Lutz, S. Neubauer, M. Heck, T. Kuhr, A. Zupanc, I. Adachi, H. Aihara, D. M. Asner, T. Aushev, T. Aziz, [......], P. Wang, M. Watanabe, Y. Watanabe, K. M. Williams, E. Won, H. Yamamoto, Y. Yamashita, Z. P. Zhang, V. Zhilich, V. Zhulanov
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  ABSTRACT: We report a search for the rare decays B -> h(*) nu nubar, where h(*) stands for K+, Ks0, K*+, K*0, pi+, pi0, rho+, rho0 and phi. The results are obtained from a 711 fb-1 data sample that contains 772 million BB pairs collected at the Y(4S) resonance with the Belle detector at the KEKB e+e- collider. We search for signal candidates by fully reconstructing a hadronic decay of the accompanying B meson and requiring a single h(*) meson left on the signal side. No significant signal is observed and we set upper limits on the branching fractions at 90% confidence level. The measurements of B+ -> K*+ nu nubar, B+ -> pi+ nu nubar, B0 -> pi0 nu nubar and B0 -> rho^0 nu nubar provide the world's currently most restrictive limits.
  03/2013;
• Article: Measurement of the Cross Section for Prompt Isolated Diphoton Production Using the Full CDF Run II Data Sample.

  T Aaltonen, S Amerio, D Amidei, A Anastassov, A Annovi, J Antos, G Apollinari, J A Appel, T Arisawa, A Artikov, [......], K Yi, J Yoh, K Yorita, T Yoshida, G B Yu, I Yu, A M Zanetti, Y Zeng, C Zhou, S Zucchelli
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  ABSTRACT: This Letter reports a measurement of the cross section for producing pairs of central prompt isolated photons in proton-antiproton collisions at a total energy sqrt[s]=1.96 TeV using data corresponding to 9.5 fb^{-1} integrated luminosity collected with the CDF II detector at the Fermilab Tevatron. The measured differential cross section is compared to three calculations derived from the theory of strong interactions. These include a prediction based on a leading order matrix element calculation merged with a parton shower model, a next-to-leading order calculation, and a next-to-next-to-leading order calculation. The first and last calculations reproduce most aspects of the data, thus showing the importance of higher-order contributions for understanding the theory of strong interaction and improving measurements of the Higgs boson and searches for new phenomena in diphoton final states.
  Physical Review Letters 03/2013; 110(10):101801. · 7.37 Impact Factor
• Article: Measurement of the CP Violation Parameters in B0 -> pi+ pi- Decays

  Belle Collaboration, I. Adachi, K. Adamczyk, H. Aihara, K. Arinstein, Y. Arita, D. M. Asner, T. Aso, V. Aulchenko, T. Aushev, [......], L. M. Zhang, Z. P. Zhang, L. Zhao, V. Zhilich, P. Zhou, V. Zhulanov, T. Zivko, A. Zupanc, N. Zwahlen, O. Zyukova
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  ABSTRACT: We present a measurement of the time-dependent CP violation parameters in B0 -> pi+ pi- decays. The results are obtained from the final data sample containing 772 million BBbar pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. We obtain the CP violation parameters Acp = +0.33 +/- 0.06 (stat) +/- 0.03 (syst) and Scp = -0.64 +/- 0.08 (stat) +/- 0.03 (syst), where Acp and Scp represent direct and mixing-induced CP violation, respectively. From an isospin analysis including results from other Belle measurements, we rule out 23.8 < phi2 < 66.8 degrees at the 1 sigma level.
  02/2013;
• Article: Precision measurement of charged pion and kaon multiplicities in electron-positron annihilation at Q = 10.52 GeV

  Belle Collaboration, M. Leitgab, R. Seidl, M. Grosse Perdekamp, A. Vossen, I. Adachi, H. Aihara, D. M. Asner, V. Aulchenko, T. Aushev, [......], J. Wang, M. -Z. Wang, P. Wang, M. Watanabe, Y. Watanabe, K. M. Williams, E. Won, Y. Yamashita, V. Zhilich, V. Zhulanov
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  ABSTRACT: Precise measurements of inclusive multiplicities of charged pions and kaons produced in electron-positron annihilation have been carried out at a center-of-mass energy of 10.52 GeV. The measurements were performed with the Belle detector at the KEKB electron-positron collider using a data sample containing 113 million e+e- -> qqbar events, where q={u,d,s,c}. We present charge-integrated multiplicities 1/N_evts * dN_h+-/dz for h+- = pi+-, K+- as a function of the relative hadron energy z = 2*E_h / sqrt{s} from 0.2 to 0.98 (0.97) for pions (kaons). The combined statistical and systematic uncertainties for pi+- (K+-) are 4% (5%) at z ~ 0.6 and 18% (51%) at z ~ 0.9. The multiplicities are the first measurements of the z-dependence of pion and kaon multiplicities for z > 0.7 as well as the first precision multiplicity measurements at a center-of-mass energy far below the Z^0 resonance used by the experiments at LEP and SLC.
  01/2013;
• Source

  Available from: A. Ruiz

  Article: Updated search for the standard model Higgs boson in events with jets and missing transverse energy using the full CDF data set

  CDF Collaboration, T. Aaltonen, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, J. A. Appel, T. Arisawa, [......], K. Yi, J. Yoh, K. Yorita, T. Yoshida, G. B. Yu, I. Yu, A. M. Zanetti, Y. Zeng, C. Zhou, S. Zucchelli
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  ABSTRACT: We present an updated search for the Higgs boson produced in association with a vector boson in the final state with missing transverse energy and two jets. We use the full CDF data set corresponding to an integrated luminosity of 9.45 fb${}^{-1}$ at a proton-antiproton center-of-mass energy of $\sqrt{s}=1.96$ TeV. New to this analysis is the inclusion of a $b$-jet identification algorithm specifically optimized for $H\to b\bar{b}$ searches. Across the Higgs boson mass range $90 \le m_H \le 150$ GeV$/c^2$, the expected 95% credibility level upper limits on the $V H$ production cross section times the $H\to b\bar{b}$ branching fraction are improved by an average of 14% relative to the previous analysis. At a Higgs boson mass of 125 GeV$/c^2$, the observed (expected) limit is 3.06 (3.33) times the standard model prediction, corresponding to one of the most sensitive searches to date in this final state.
  01/2013;
• Article: Search for heavy neutrinos at Belle

  Belle Collaboration, D. Liventsev, I. Adachi, H. Aihara, K. Arinstein, D. M. Asner, V. Aulchenko, T. Aushev, A. M. Bakich, A. Bay, [......], Y. Watanabe, K. M. Williams, E. Won, B. D. Yabsley, H. Yamamoto, Y. Yamashita, C. C. Zhang, Z. P. Zhang, V. Zhilich, A. Zupanc
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  ABSTRACT: We report on a search for heavy neutrinos in B-meson decays. The results are obtained using a data sample that contains 772x10^6 BB-bar pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. No signal is observed and upper limits are set on mixing of heavy neutrinos with left-handed neutrinos of the Standard Model in the mass range 0.5 - 5.0 GeV/c^2.
  01/2013;
• Article: Measurement of the inclusive semileptonic branching fraction Bf(B_s^0 -> X^- l^+ nu) at Belle

  Belle Collaboration, C. Oswald, P. Urquijo, J. Dingfelder, I. Adachi, H. Aihara, K. Arinstein, D. M. Asner, T. Aushev, A. M. Bakich, [......], M. Watanabe, Y. Watanabe, K. M. Williams, E. Won, H. Yamamoto, Y. Yamashita, C. C. Zhang, Z. P. Zhang, V. Zhilich, A. Zupanc
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  ABSTRACT: We report a measurement of the inclusive semileptonic B_s^0 branching fraction in a 121 fb^{-1} data sample collected near the Upsilon(5S) resonance with the Belle detector at the KEKB asymmetric energy e^+ e^- collider. Events containing B_s^0 pairs are selected by reconstructing a tag side D_s^+ and identifying a signal side lepton l^+ (l = e, mu) that is required to have the same-sign charge to ensure that both originate from different B_s^0 mesons. The B_s^0 -> X^- l^+ nu branching fraction is extracted from the ratio of the measured yields of D_s^+ mesons and D_s^+ l^+ pairs and the known production and branching fractions. The inclusive semileptonic branching fraction is measured to be [10.6 +/- 0.5(stat) +/- 0.7(syst)] %.
  12/2012;
• Article: Search for CP Violation in the Decay $D^+\rightarrow K^0_S K^+$

  B. R. Ko, E. Won, I. Adachi, H. Aihara, K. Arinstein, D. M. Asner, T. Aushev, A. M. Bakich, K. Belous, V. Bhardwaj, [......], G. Varner, C. H. Wang, M. -Z. Wang, P. Wang, Y. Watanabe, K. M. Williams, Y. Yamashita, C. C. Zhang, V. Zhilich, A. Zupanc
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  ABSTRACT: We search for CP violation in the decay $D^+\rightarrow K^0_S K^+$ using a data sample with an integrated luminosity of 977 fb$^{-1}$ collected with the Belle detector at the KEKB $e^+e^-$ asymmetric-energy collider. No CP violation has been observed and the CP asymmetry in $D^+\rightarrow K^0_S K^+$ decay is measured to be $(-0.25\pm0.28\pm0.14)%$, which is the most sensitive measurement to date. After subtracting CP violation due to $K^0-\bar{K}^0$ mixing, the CP asymmetry in $D^+\rightarrow\bar{K}^0 K^+$ decay is found to be $(+0.08\pm0.28\pm0.14)%$.
  12/2012;
• Article: Study of B^0 -> rho^0 rho^0 decays, implications for the CKM angle phi_2 and search for other four pion final states

  I. Adachi, K. Adamczyk, H. Aihara, K. Arinstein, Y. Arita, D. M. Asner, T. Aso, V. Aulchenko, T. Aushev, T. Aziz, [......], L. M. Zhang, Z. P. Zhang, L. Zhao, V. Zhilich, P. Zhou, V. Zhulanov, T. Zivko, A. Zupanc, N. Zwahlen, O. Zyukova
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  ABSTRACT: We present a study of the branching fraction of the decay B^0 -> rho^0 rho^0 and the fraction of longitudinally polarized \rho^0 mesons in this decay. The results are obtained from the final data sample containing $772 \times 10^{6}$ $B\bar{B}$ pairs collected at the $\Upsilon(4S)$ resonance with the Belle detector at the KEKB asymmetric-energy e^+e^- collider. We find $166 \pm 59$ B^0 -> rho^0 rho^0 events, corresponding to a branching fraction of ${\cal B}(B^0 -> rho^0 rho^0) = (1.02\pm 0.30 (\rm stat) \pm 0.22 (\rm syst))\times 10^{-6} $ with a longitudinally polarization fraction $f_L = 0.21^{+0.18}_{-0.22} (\rm stat) \pm 0.11 (\rm syst)$. The branching fraction's upper limit is ${\cal B}(B^0 -> rho^0 rho^0) < 1.5 \times 10^{-6}$ at 90% confidence level. We use the longitudinal polarization fraction to determine the Cabibbo-Kobayashi-Maskawa matrix angle $\phi_2 = (91.0 \pm 7.2)^{\circ}$ through an isospin analysis in the $B\to\rho\rho$ system. We furthermore obtain ${\cal B}(B^0 -> rho^0 f_0) \times {\cal B}(f_0 -> \pi^+\pi^-) = (0.86 \pm 0.27 (\rm stat) \pm 0.15 (\rm syst))\times 10^{-6}$, corresponding to $149 \pm 49$ $B^0 -> rho^0 f_0$ events with a significance of 3.0 standard deviations and upper limits at 90% confidence level on the (product) branching fractions for possible decays with the same final state, ${\cal B}(B^0 -> pi^+\pi^-pi^+\pi^-) < 11.7 \times 10^{-6} $, ${\cal B}(B^0 -> rho^0 pi^+\pi^-) < 12.2 \times 10^{-6}$, ${\cal B}(B^0 -> f_0 pi^+\pi^-) \times {\cal B}(f_0->\pi^+\pi^-) < 3.1 \times 10^{-6}$ and ${\cal B}(B^0 -> f_0 f_0) \times {\cal B}(f_0->\pi^+\pi^-)^{2} < 0.2 \times 10^{-6}$.
  12/2012;
• Article: Evidence for the η_{b}(2S) and Observation of h_{b}(1P)→η_{b}(1S)γ and h_{b}(2P)→η_{b}(1S)γ

  R Mizuk, D M Asner, A Bondar, T K Pedlar, I Adachi, H Aihara, K Arinstein, V Aulchenko, T Aushev, T Aziz, [......], M Watanabe, Y Watanabe, K M Williams, E Won, B D Yabsley, J Yamaoka, Y Yamashita, C Z Yuan, Z P Zhang, V Zhilich
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  ABSTRACT: We report the first evidence for the η_{b}(2S) using the h_{b}(2P)→η_{b}(2S)γ transition and the first observation of the h_{b}(1P)→η_{b}(1S)γ and h_{b}(2P)→η_{b}(1S)γ transitions. The mass and width of the η_{b}(1S) and η_{b}(2S) are measured to be m_{η_{b}(1S)}=(9402.4±1.5±1.8) MeV/c^{2}, m_{η_{b}(2S)}=(9999.0±3.5_{-1.9}^{+2.8}) MeV/c^{2}, and Γ_{η_{b}(1S)}=(10.8_{-3.7-2.0}^{+4.0+4.5}) MeV. We also update the h_{b}(1P) and h_{b}(2P) mass measurements. We use a 133.4 fb^{-1} data sample collected at energies near the Υ(5S) resonance with the Belle detector at the KEKB asymmetric-energy e^{+}e^{-} collider.
  Physical Review Letters 12/2012; 109(23):232002. · 7.37 Impact Factor
• Article: 41 RAPID PRODUCTION OF α-1,3-GALACTOSYLTRANSFERASE-DEFICIENT MINIATURE PIGS BY NUCLEAR TRANSFER FOLLOWING NEONATAL SKIN BIOPSY AND LOSS OF HETEROZYGOSITY.

  Y J Kim, M J Kim, J S Ahn, J H Ryu, S Y Heo, S M Park, J H Kang, Y J Choi, K S Ahn, H Shim
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  ABSTRACT: Production of α-1,3-galactosyltransferase (αGT)-deficient pigs is a fundamental task to overcome hyperacute rejection in pig-to-human xenotransplantation. However, the procedure to produce such pigs requires a great deal of cost, time, and labor. Heterozygote αGT knockout (KO) pigs should be bred at least for 2 generations to ultimately produce homozygote progenies. Here, we show that αGT-deficient miniature pigs could be produced in much reduced time using mitotic recombination in neonatal ear skin fibroblasts. Miniature pig fetal fibroblasts were transfected with αGT-targeting vector and treated with neomycin. Eighty-seven colonies were screened by PCR, and 2 among them were identified as homologous recombinants with monoallelic disruption of αGT (targeting efficiency=2.3%). One of the two colonies was chosen and used for subsequent NT. In total, 559 nuclear transfer embryos reconstructed with αGT gene-targeted fetal fibroblasts were transferred to 5 surrogate gilts. Three gilts became pregnant and developed to term with 3 live piglets delivered. Being analyzed by PCR, all piglets born were found to be αGT gene targeted. Fibroblasts were isolated from ear skin biopsies of a 10-day-old αGT gene-targeted miniature pig. To increase the number of mitotic recombination that occurs spontaneously during cell proliferation, fibroblasts were cultured for 6 to 8 passages. Then, these cells were treated with IB4-conjugated Dynabeads; IB4 lectin binds to galactose-α-1,3-galactose (αGal), the antigen formed by αGT, and is responsible for hyperacute rejection (HAR). Using a magnetic column, fibroblasts bound to IB4 lectin were removed. Remaining cells lacking αGal were cultured further until colony formation. A total of 22 fibroblast colonies were screened by PCR, and 15 among them were confirmed as loss of heterozygosity (LOH) with biallelic disruption of αGT by mitotic recombination (LOH efficiency=68%). One of these clonal cultures of αGT-deficient fibroblasts was chosen and used for subsequent NT. In total, 729 nuclear transfer embryos reconstructed with αGT-deficient neonatal ear skin fibroblasts were transferred to 4 surrogate gilts. Two gilts became pregnant, and 3 live piglets were produced. Based on PCR, both αGT alleles were targeted in all piglets born. Only 8 months were required from the production of heterozygote to homozygote KO in contrast to approximately 2 years consumed for conventional breeding of heterozygotes. The present study demonstrates that the time required for the production of αGT-deficient miniature pigs could be reduced significantly by neonatal skin biopsies and subsequent selection of mitotic recombinants. Such a procedure may be beneficial for the production of other homozygote KO animals, especially in species that require substantial periods of gestation such as pigs.
  Reproduction Fertility and Development 12/2012; 25(1):168. · 2.11 Impact Factor
• Article: Claudin-1 induces epithelial-mesenchymal transition through activation of the c-Abl-ERK signaling pathway in human liver cells.

  Y Suh, C-H Yoon, R-K Kim, E-J Lim, Y S Oh, S-G Hwang, S An, G Yoon, M C Gye, J-M Yi, M-J Kim, S-J Lee
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  ABSTRACT: Claudins (CLDNs) are a family of integral membrane proteins central to the formation of tight junctions, structures that are involved in paracellular transport and cellular growth and differentiation, and are critical for the maintenance of cellular polarity. Recent studies have provided evidence that CLDNs are aberrantly expressed in diverse types of human cancers, including hepatocellular carcinomas (HCCs). However, little is known about how CLDN expression is involved in cancer progression. In this study, we show that CLDN1 has a causal role in the epithelial-mesenchymal transition (EMT) in human liver cells, and that the c-Abl-Ras-Raf-1-ERK1/2 signaling axis is critical for the induction of malignant progression by CLDN1. Overexpression of CLDN1 induced expression of the EMT-regulating transcription factors Slug and Zeb1, and thereby led to repression of E-cadherin, β-catenin expression, enhanced expression of N-cadherin and Vimentin, a loss of cell adhesion, and increased cell motility in normal liver cells and HCC cells. In line with these findings, inhibition of either c-Abl or ERK clearly attenuated CLDN1-induced EMT, as evidenced by a reversal of N-cadherin and E-cadherin expression patterns, and restored normal motility. Collectively, these results indicate that CLDN1 is necessary for the induction of EMT in human liver cells, and that activation of the c-Abl-Ras-Raf-1-ERK1/2 signaling pathway is required for CLDN1-induced acquisition of the malignant phenotype. The present observations suggest that CLDN1 could be exploited as a biomarker for liver cancer metastasis and might provide a pivotal point for therapeutic intervention in HCC.Oncogene advance online publication, 19 November 2012; doi:10.1038/onc.2012.505.
  Oncogene 11/2012; · 6.37 Impact Factor
• Article: Outbreaks and Diagnosis of Foot-and-Mouth Disease Serotype O in the Republic of Korea, April-June 2010.

  J-H Park, K-N Lee, Y-J Ko, S-M Kim, H-S Lee, J-Y Park, J-Y Yeh, M-J Kim, Y-H Lee, H-J Sohn, J-S Moon, I-S Cho, B Kim
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  ABSTRACT: Thirteen outbreaks of foot-and-mouth disease (FMD) were reported in pigs and cattle in Korea between 8 April and 4 June 2010. The FMD virus (FMDV) isolates were of serotype O, indicating that they were related to the virus strains of the Southeast Asia topotype that are circulating in East Asian countries. Animals carrying the viruses were identified by reverse transcriptase-polymerase chain reaction (RT-PCR) during a 29-day period between 8 April and 6 May, 2010. Prior to this outbreak, these FMDVs had not been detected in Korea and may therefore have been introduced from neighbouring countries into Ganghwa Island and subsequently spread inland to other areas, including Gimpo, Chungju and Cheongyang. Tests conducted to lift restrictions on animal movements lead to detection of two additional FMD-positive farms. Through appropriate responses, including swift diagnoses and culling policies, Korea was able to quickly regain its recognition as being free of FMD, without vaccination, by the World Organization for Animal Health (OIE) on 27 September 2010.
  Transboundary and Emerging Diseases 11/2012; · 1.81 Impact Factor
• Article: Measurements of the Top-Quark Mass and the tt[over ¯] Cross Section in the Hadronic τ+jets Decay Channel at sqrt[s]=1.96  TeV.

  T Aaltonen, B Alvarez González, S Amerio, D Amidei, A Anastassov, A Annovi, J Antos, G Apollinari, J A Appel, T Arisawa, [......], K Yorita, T Yoshida, G B Yu, I Yu, S S Yu, J C Yun, A Zanetti, Y Zeng, C Zhou, S Zucchelli
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  ABSTRACT: We present the first direct measurement of the top-quark mass using tt[over ¯] events decaying in the hadronic τ+jets decay channel. Using data corresponding to an integrated luminosity of 2.2  fb^{-1} collected by the CDF II detector in pp[over ¯] collisions at sqrt[s]=1.96  TeV at the Fermilab Tevatron, we measure the tt[over ¯] cross section, σ_{tt[over ¯]}, and the top-quark mass, M_{top}. We extract M_{top} from a likelihood based on per-event probabilities calculated with leading-order signal and background matrix elements. We measure σ_{tt[over ¯]}=8.8±3.3(stat)±2.2(syst)  pb and M_{top}=172.7±9.3(stat)±3.7(syst)  GeV/c^{2}.
  Physical Review Letters 11/2012; 109(19):192001. · 7.37 Impact Factor
• Article: Measurement of the top quark forward-backward production asymmetry and its dependence on event kinematic properties

  CDF Collaboration, T. Aaltonen, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, J. A. Appel, T. Arisawa, [......], K. Yi, J. Yoh, K. Yorita, T. Yoshida, G. B. Yu, I. Yu, A. M. Zanetti, Y. Zeng, C. Zhou, S. Zucchelli
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  ABSTRACT: We present new measurements of the inclusive forward-backward ttbar production asymmetry, AFB, and its dependence on several properties of the ttbar system. The measurements are performed with the full Tevatron data set recorded with the CDF II detector during ppbar collisions at sqrt(s) = 1.96 TeV, corresponding to an integrated luminosity of 9.4 fb^(-1). We measure the asymmetry using the rapidity difference Delta-y=y_(t)-y_(tbar). Parton-level results are derived, yielding an inclusive asymmetry of 0.164+/-0.047 (stat + syst). We observe a linear dependence of AFB on the top-quark pair mass M(ttbar) and the rapidity difference |Delta-y| at detector and parton levels. Assuming the standard model, the probabilities to observe the measured values or larger for the detector-level dependencies are 7.4*10^(-3) and 2.2*10^(-3) for M(ttbar) and |Delta-y| respectively. Lastly, we study the dependence of the asymmetry on the transverse momentum of the ttbar system at the detector level. These results are consistent with previous lower-precision measurements and provide additional quantification of the functional dependencies of the asymmetry.
  11/2012;