A Omezzine Letaief

Publications (4)5.47 Total impact

• Article: Infection in systemic lupus erythematosus.

  M Khalifa, N Kaabia, F Bahri, E Ben Jazia, E Bouajina, A Omezzine Letaief
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  ABSTRACT: Infections are common in patients with systemic lupus erythematosus (SLE) throughout the course of their disease and remain a source of mortality. The aim of this study was to determine the prevalence of infections, to describe their nature, and analyze their risk factors in adults with SLE. We performed a descriptive study, at the Farhat-Hached Hospital in Sousse, and retrospectively analyzed the charts of 75 patients with SLE seen between 1990 and 2004. The group of patients with documented infections was compared to a control group. A logistic regression analysis was performed to determine risk factors associated with infection. Our study included 64 women and 11 men (median age of 31.4 years). Forty-three patients (57.5%) had 82 infectious episodes: 23 patients had at least two infectious episodes. Most infections were community acquired, and 80% were severe. The most common infections involved the urinary tract (28%), the skin and soft tissue (26.8%), and the respiratory tract (18.3%). Documented pathogens were: 45 common bacteria, 11 Candida albicans and four Mycobacterium tuberculosis. Localized herpes zoster was noted in three cases. Factors associated with infection, found in univariate analysis, were renal involvement, serum albumin lower than 25 g/l, and corticosteroids treatment. Only corticosteroids therapy remained statistically significant after multivariate analysis.
  Médecine et Maladies Infectieuses 01/2008; 37(12):792-5. · 0.72 Impact Factor
• Article: Regression of skin lesions of Kyrle's disease with metronidazole in a diabetic patient.

  M Khalifa, I Slim, N Kaabia, F Bahri, A Trabelsi, A Omezzine Letaief
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  ABSTRACT: We describe here in a case of a 41-year-old man, with diabetes mellitus, who presented manifestations of Kyrle's disease. Administration of metronidazole, 500 mg twice daily for 1 month, resulted in complete regression of skin lesions with no recurrence during 12 months of follow-up. This successful antibiotic treatment is to support the role of infectious agents (anaerobic bacteria) in the pathogenesis of Kyrle's disease.
  The Journal of infection 01/2008; 55(6):e139-40. · 4.13 Impact Factor
• Article: [Prolonged fever in adults with normal sedimentation rate].

  A Omezzine Letaief, F Bahri, M Ernez, L Jemni
  Annales de medecine interne 01/1997; 148(4):327-8.
• Article: [Pyomyositis in adults in central Tunisia. Apropos of 10 cases].

  T Chekir, A Omezzine Letaief, F Bahri, A Jamel, S Aloui, L Jemni
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  ABSTRACT: Ten adult patients treated for pyomyositis between 1988 and 1994 in Sousse's university hospital (Tunisia) were retrospectively reviewed. Due to the non specific symptoms, the diagnosis was often delayed (mean = 17 days) and other primary diagnoses were considered, mainly including synovitis. The muscles around hip and thigh were most commonly involved (ten patients), and Staphylococcus aureus was the most common pathogen (nine patients). Ultrasonography was very helpful in the accurate diagnosis of the infection. Incision, drainage, and antibiotic therapy eradicated the infection in all patients. No residual functional limitations and no residual symptoms were noted. Our study showed that pyomyositis is present in central Tunisia and not associated with HIV infection. Clinical features and prognosis are similar to those previously described in the literature.
  La Revue de Médecine Interne 02/1996; 17(4):300-4. · 0.61 Impact Factor