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Medical science monitor: international medical journal of experimental and clinical research 01/2013; 19:202. · 1.70 Impact Factor
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Lung India 01/2013; 30(1):82-5.
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American journal of obstetrics and gynecology 12/2012; · 3.28 Impact Factor
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Radiology 12/2012; 265(3):979-80. · 5.73 Impact Factor
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Michele Scialpi,
Cristiano Franzini,
Irene Piscioli,
Francesco Barberini,
Teresa Pusiol,
Fabio Rondelli,
Virgilio Nicolanti,
Antonio Rulli,
Paolo Izzo,
Gianluca Merlin,
Anna Rita Forcione,
Federico Pugliese,
Pierfrancesco Di Cello,
Annalisa Paliotta,
Luciano Izzo
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ABSTRACT: QUESTION OF THE STUDY: Synchronous primary lung cancers (SPLCs) may pose a radiologic-pathologic and therapeutic dilemma in according to recent WHO classification. PATIENTS AND METHODS: Two cases of surgically treated SPLCs are reported. RESULTS: In the first case two nodules were detected by Computed Tomography (CT) in the upper right lobe. The patient underwent lobectomy and histological diagnosis was adenocarcinoma and squamous cell carcinoma. The second patient presented at CT one nodule in the upper left lobe and another nodule in the upper right lobe. Sternotomic access was chosen for bilateral removal of the lesions. The diagnosis was sarcomatoid carcinoma and large cell neuroendocrine adenocarcinoma. DISCUSSION: The criteria of Martini and Melamed are inadequate for the diagnosis of SPLCs. The use of TTF-1 (thyroid transcription factor-1) is necessary to establish the diagnosis of SPLC in patients with adenocarcinoma of other sites. Bronchioloalveolar carcinomas must be excluded because of their multicentricity. When histology of two tumors found in the same lobe is identical and histotype is adenocarcinoma, large cell carcinoma or sarcomatoid carcinoma, the diagnosis of SPLCs must be excluded and those lesions must be considered as metastatic disease. The prognosis and treatment of SPLCs are discussed after critical review of the literature. KEY WORDS: Large cell neuroendocrine cancers, Sarcomatoid carcinoma, Synchronous primary lung cancers.
Annali italiani di chirurgia 11/2012; · 0.23 Impact Factor
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ABSTRACT: The aim of this study was to define enhancement patterns of small renal cell carcinoma (RCC) (≤4 cm) by triphasic spiral CT. In 24 patients with RCC, hypervascularity and hypovascularity were identified in 12 and 12 RO, respectively, in the cortico-medullary phase (CMP). Hypervascular RCC showed increased density in the CMP (170,7±46,3 UH) and a gradual wash-out in the nephrographic phase (NP) (152,5±41 UH) and pielographic phase (PF) (99,2±38 UH). Hypovascular RCC showed increased density in the CMP (52,9±24,7 UH) and a gradual wash-out in NP (64,5±16,9 UH) and PP phases (55,0±17,3 UH).
Recenti progressi in medicina 11/2012; 103(11):471-6.
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ABSTRACT: In 18 patients with 19 RO, 9 hypervascularity and hypovascularity was identified in 9 and 10 RO, respectively, in the cortico-medullary phase (CMP). Hypervascular RO showed increased density in the CMP (151.4±38.5 HU) and a gradual wash-out in the nephrographic phase (133.8±34.6 HU) and excretory phase (79±23 HU). Hypovascular RO showed increased density in the CMP (87.8±20.1 UH) and a gradual wash-out in the nephrographic phase (100.3±33 UH) and excretory phase (20.9±86.9 UH).
Recenti progressi in medicina 11/2012; 103(11):477-82.
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ABSTRACT: The authors emphasize the role of CT in the preoperative diagnosis of a giant benign solitary fibrous tumor of the pleura. CT can provide evidence of complete resection of the lesion, showing a pedunculated stalk. Aspiration cytology is not a reliable diagnostic approach.
Recenti progressi in medicina 11/2012; 103(11):520-2.
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ABSTRACT: We report the case of a 78-year-old man presenting with pain in right hemithorax that occurred suddenly after coughing. A palpable chest wall mass, soft in consistency, was noted on physical examination, and chest X-ray and CT allowed to make diagnosis of spontaneous lung hernia.
Recenti progressi in medicina 11/2012; 103(11):523-5.
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Radiology 03/2012; 262(3):1044-5; author reply 1045. · 5.73 Impact Factor
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ABSTRACT: Our aim was to evaluate the different clinical value of (111)In-pentetreotide hybrid SPET/CT versus SPET alone in detecting carcinoid tumours located in the thoracic and abdominal region. Twenty-four patients with carcinoid tumours histologically proven (13 of abdominal origin, 11 of thoracic origin) underwent (111)In-pentetreotide SPET/CT with hybrid system (Millennium VG with Hawkeye, G.E.M.S., USA) composed of a dual head gamma camera equipped with a low dose X-ray tube. Single photon emission tomography images were performed 4h and 24h after (111)In-pentetreotide intravenous administration, while SPET/CT co-registered images were performed at 4h. Scintigraphic images were first evaluated alone and then re-interpreted by adding transmission fused data. Nine of the 13 patients with tumours of abdominal origin showed pathological SPET images, while 4/13 were negative. Seven out of the 11 patients with tumour of thoracic origin had pathological SPET findings, while 4/11 were negative. In all, 11/24 subjects disclosed abdominal pathological uptake and 10/24 thoracic. In 6/11 abdominal cases SPET/CT allowed anatomical localization of lesions, while in 2/10 in thoracic cases. Additional data were provided by SPET/CT in 8/24 cases (6 abdominal, 2 thoracic), by transmission images characterized as lesions not expressing somatostatin receptors. Sensitivity of SPET alone in all carcinoids was 72%, negative predictive value (NPV) was 50% and accuracy was 78%. Considering abdominal lesions (independently of the origin) sensitivity of SPET alone was 64.7%, NPV was 40%, accuracy was 71.4%. For thoracic lesions sensitivity of SPET alone was 83.3%, NPV was 66.7% and accuracy was 87.5%. For SPET/CT considering together all carcinoids and also separately lesions of abdominal and of thoracic origin, sensitivity, NPV and accuracy were always 100%. In conclusion, SPET/CT imaging was more useful to anatomically detect carcinoids either in abdomen or in thorax and specifically lesions not expressing somatostatin receptors, as compared to SPET alone.
Hellenic journal of nuclear medicine 09/2011; 14(3):274-7. · 0.81 Impact Factor
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Urologia Internationalis 06/2011; 87(1):125-6. · 0.99 Impact Factor
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World Journal of Urology 05/2011; · 2.41 Impact Factor
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Radiology 11/2010; 257(2):587-8; author reply 588. · 5.73 Impact Factor
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ABSTRACT: We evaluated local recurrence, toxicity rate and cosmetic outcome in 72 patients treated with high-dose-rate (HDR) brachytherapy after breast conserving surgery. HDR brachytherapy was administered: i) as partial breast irradiation (PBI) in 64 patients with low-risk early stage breast cancer, enrolled in a phase II prospective study; ii) as PBI after a second conservative surgery as treatment of local relapse in 3 patients; iii) for delivering a boost after whole breast external beam radiotherapy in 5 patients. Implantation was done during surgery (breast conserving or re-excision to achieve adequate surgical margins), with the wound open, or postoperatively. The implant was well tolerated in all patients, so no premature catheter removal was required. At a median follow-up of 32 months (range 5-52) no local recurrence has been observed. Toxicity was very low. Cosmetic outcome was excellent/good in a high percentage of patients. Our results suggest that PBI administered with HDR brachytherapy is feasible in selected patients with low risk early stage breast carcinoma. PBI seems feasible to repeat radiotherapy after a salvage breast conserving surgery for local relapse in a second attempt to preserve the breast.
Oncology Reports 08/2010; 24(2):417-22. · 1.84 Impact Factor
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Radiology 02/2010; 254(2):634; author reply 635. · 5.73 Impact Factor
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Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 02/2010; 32(1):58-60. · 0.41 Impact Factor
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Surgery Today 01/2010; 40(1):92. · 1.22 Impact Factor
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Radiology 10/2009; 252(3):929; author reply 930-1. · 5.73 Impact Factor
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International Journal of Gynecological Cancer 06/2009; 19(4):811. · 1.65 Impact Factor
