Orhan Kemal Kahveci

Publications (9)8.99 Total impact

• Article: The effect of retinyl palmitate on healing of benign vocal fold lesions.

  Erdogan Okur, Orhan Kemal Kahveci, Abdullah Aycicek, Ali Altuntaş
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  ABSTRACT: The leading cause of vocal fold lesions such as nodules and polyps is phonotrauma, which causes microhematoma formation in the vocal fold cover that can initiate an inflammatory process. Vitamin A (Vit A) is essential for immunity, cellular differentiation and maintenance of respiratory epithelium. The aim of this study is to investigate the effect of Vit A (retinyl palmitate) on healing of vocal fold lesions, including vocal polyps and nodules. Eighteen patients with vocal fold lesions were included in the study. Of the patients, 13 had vocal polyps and 5 had vocal nodules. Patients received 90,000 IU oral Vit A in palmitate form daily for 2 months. In addition to Vit A treatment, only vocal hygiene recommendations were given to the patients, without any other medication or specific voice therapy. Pre- and post-treatment acoustic analysis [jitter % (jitt %), shimmer % (shim %), normalized noise energy (NNE), maximum phonation time (MPT), etc.] were performed. Lesion dimensions and stroboscopic findings were evaluated. Voice handicap index (VHI) was applied. Statistical analysis was performed between pre- and post-treatment measurements. Of the 18 patients, 8 had immature lesions (6 polyp-like lesions and 2 immature nodules) and 10 had mature lesion (7 polyps and 3 nodules). None of the patients showed complete healing. Partial response was seen in four patients with immature lesions. There were minimal changes in lesion dimensions, but this difference did not reach statistical significance. MPT of patients with immature lesions were close to significance level but overall MPT revealed no significant improvement (p = 0.051). Jitt %, shim % and NNE did not change significantly. In this study, the only statistically significant finding was VHI of the patients with immature lesions. Three of the patients complained of weight gain. Our data showed that Vit A at a given level of dose and duration seems to be ineffective in the treatment of benign vocal fold lesions. On the other hand, whether Vit A is effective on mature and immature lesions of vocal folds at higher doses and/or longer duration of treatment or not requires further studies.
  Archives of Oto-Rhino-Laryngology 08/2012; · 1.29 Impact Factor
• Article: Hearing and cochlear function of patients with ankylosing spondylitis.

  Orhan Kemal Kahveci, Umit Secil Demirdal, Abidin Duran, Ali Altuntas, Vural Kavuncu, Erdogan Okur
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  ABSTRACT: Ankylosing spondylitis (AS) is a chronic systemic inflammatory disorder that primarily affects the spine and sacroiliac joints. Recent studies described audiovestibular impairment in AS patients. The aim of this study was to evaluate the hearing and function of the cochlear system in patients with AS. Thirty-seven AS patients and 20 healthy controls were evaluated prospectively. Otorhinolaryngologic examinations were performed in all patients together with pure tone audiometry, speech discrimination test, tympanometry, and distortion product otoacoustic emission (DPOE). Disease duration, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) scores, and hematologic findings (CRP and ESR) were also collected. Pure tone audiometry findings of the patients and controls were significantly different in all frequencies (p < 0.01). Speech discrimination scores were also significantly different (p < 0.01). No significant difference was found between DPOE responses of the patients and controls (p > 0.05). There was no correlation between disease duration, BASDAI scores, hematological findings, and audiometry findings (p > 0.05). This study demonstrated that there is an association between AS and hearing loss, but the cochlea is not the main source of hearing loss.
  Clinical Rheumatology 04/2012; 31(7):1103-8. · 2.00 Impact Factor
• Article: Combined medical and surgical therapy improves olfaction in patients with nasal polyposis.

  Abdullah Ayçiçek, Orhan Kemal Kahveci, Murat Cem Miman, Abidin Duran, Hüseyin Yildiz
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  ABSTRACT: The aim of the present study was to evaluate the outcomes of combined oral steroid, nasal steroid and surgical therapy in patients with impaired olfaction due to nasal polyposis. This prospective observational study was undertaken in the otolaryngology department of a university hospital. During the study, 19 nasal polyposis patients were evaluated three times, i.e. before oral steroid therapy, before surgery (after steroid therapy) and after surgery, with smell identification tests, acoustic rhinometry, subjective smell score, endoscopic grading and a visual analog scale for nasal obstruction. All subjective and objective measures were significantly improved after medical and surgical therapy (p < 0.01). The median smell identification score improved from 2 (interquartile range 0-4) to 5 (interquartile range 4-7) after combined therapy. Smell identification scores were found to be modestly correlated with all other examination findings. Combined therapy seems efficient in improving smell identification scores of nasal polyposis patients.
  ORL 03/2012; 74(2):110-5. · 0.91 Impact Factor
• Article: The efficiency of Nose Obstruction Symptom Evaluation (NOSE) scale on patients with nasal septal deviation.

  Orhan Kemal Kahveci, Murat Cem Miman, Aylin Yucel, Fatih Yucedag, Erdoğan Okur, Ali Altuntas
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  ABSTRACT: The aim in this study was to evaluate the efficiency of Nasal Obstruction Symptom Evaluation (NOSE) scale for septoplasty (without turbinate reduction) in comparison with other examination methods. Prospective observational study was undertaken in otolaryngology department of university hospital. NOSE scale for quality of life assessment, visual analog scale for examination findings, acoustic rhinometry and coronal computed tomography were performed before and after septoplasty. The efficiency of NOSE scale to assess for septoplasty results and the correlation between NOSE scores and other techniques was analyzed. Twenty-seven patients underwent septoplasty; there was a very significant improvement in mean NOSE scores of patients (60.2 versus 11.28, p<0.01). There was no correlation between NOSE scores and acoustic rhinometry. Correlation was found between NOSE scores and examination and computed tomography findings (p<0.05). NOSE scale that is well correlated with examination findings and computed tomography, is very useful tool to evaluate the effectiveness of pure septoplasty.
  Auris, nasus, larynx 08/2011; 39(3):275-9. · 0.58 Impact Factor
• Article: Metastatic basal cell carcinoma presenting as a neck mass.

  Orhan Kemal Kahveci, Erdogan Okur, Onder Sahin, Ali Altuntas, Nazan Okur, Fatma Aktepe
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  ABSTRACT: Neck masses are common in physicians' daily practice; however, there is a small possibility that the origin of the neck mass is a basal cell carcinoma (BCC). We present a BCC of the scalp that metastasizes to the neck without any lymphoid involvement. We also reviewed possible risk factors for metastasis of the BCC, which is a probable cause of neck mass.
  The Journal of craniofacial surgery 03/2010; 21(2):592-4. · 0.81 Impact Factor
• Article: Expression and distribution of aquaporin-1 in nasal polyps: does it have any significance in edema formation?

  Ali Altuntas, Mustafa Deniz Yilmaz, Fatma Aktepe, Orhan Kemal Kahveci, Sefa Derekoy, Hüsniye Dilek, Mustafa Serteser
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  ABSTRACT: The aim of this study was to investigate the expression of Aquaporin 1 (AQP1) and AQP4 in polyp tissue. Nasal polyps were obtained from 34 patients with nasal polyposis during endoscopic sinus surgery. Bullous middle turbinates with normal-appearing mucosa of 10 patients were used as controls. Expression of AQP1 and AQP4 water channels were determined by immunohistochemical methods. AQP1 has been found to be expressed in fibroblasts located in polyp tissue, especially in the subepithelial area, periphery of seromucous glands, and endothelial cells of venules. We have established a high expression of AQP1 water channels in nasal polyp tissue and have suggested two mechanisms to explain this finding. Increased AQP1 expression may be a cause or a consequence of edema formation. Thus, additional studies are needed to elucidate the true mechanism underlying this relationship.
  American Journal of Rhinology 12/2005; 20(1):128-31. · 1.36 Impact Factor
• Article: Coexistence of choanal atresia and Tessier's facial cleft number 2.

  Ali Altuntas, Mustafa Deniz Yilmaz, Orhan Kemal Kahveci, Sefa Dereköy, Aylin Yücel
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  ABSTRACT: Choanal atresia is one of the most commonly observed congenital abnormalities of the nose. This defect is frequently associated with other congenital anomalies. One of the anomalies, which is rarely encountered is a Tessier's facial cleft 2. In this report, we present a 6-year-old girl who was brought to our department with complaints of nasal obstruction and chronic nasal discharge. On examination, a scar was seen on the left ala of her nose due to the former repair of a congenital defect. We found hypoplastic nasal cavities and bilateral choanal atresia demonstrated by rigid and flexible endoscopy. A CT scan supported these findings. This coexistence of bilateral choanal atresia with a number 2 facial cleft is an addition to a formerly proposed classification of laterofacial clefts. We think that this classification is better for describing the extent and origin of these complex lesions.
  International Journal of Pediatric Otorhinolaryngology 09/2004; 68(8):1081-5. · 1.17 Impact Factor
• Article: The effects of tonsillectomy and adenoidectomy on pulmonary arterial pressure in children.

  Mustafa Deniz Yilmaz, Ersel Onrat, Ali Altuntaş, Dayimi Kaya, Orhan Kemal Kahveci, Oktay Ozel, Sefa Dereköy, Ataç Celik
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  ABSTRACT: It is well known that hypertrophic tonsils and adenoids may cause upper-airway obstruction. The aim of this study is to determine the mean pulmonary arterial pressure (mPAP) in children with hypertrophic tonsils and adenoids and to clarify whether tonsillectomy and adenoidectomy (T&A) has any effect on mean pulmonary arterial pressure of these children. Fifty-two randomly selected children (36 male, 16 female) aged between 4 and 11 (mean 7.7+/-2.5) a with a diagnosis of upper-airway obstruction resulting from hypertrophied tonsils and adenoids were included in our study. Thirty-three children were assigned as controls with similar age and sex distribution with the study groups. Mean pulmonary arterial pressure was measured by using Doppler echocardiography preoperatively and mean 5.4+/-2.9 months postoperatively in all subjects. When the mean pulmonary arterial pressure values of study and control group compared preoperatively, the mean pulmonary arterial pressure levels of the children in the study group were significantly higher than the mean pulmonary arterial pressure levels of the children in the control group (P<.05) (study group mean PAP=23.13+/-7.68, control group mean PAP=16.11+/-7.24) (Levene's test, P<.05). When the preoperative and postoperative results were compared, it was found that there was a statistically significant decrease in mean pulmonary arterial pressures in these 52 children (preoperative mean PAP=23.13+/-7.68, postoperative mean PAP=17.00+/-6.99) (paired sample t test, P<.05). Twenty-seven of the 52 subjects in the study group were pulmonary hypertensive preoperatively. mPAPs of 18 of these children decreased to normal range yielding 9 subjects, and this was also found ststistically significant (McNemar test, P<.001). This study showed that obstructive adenoid and tonsillar hypertrophy causes higher mPAP values in children and revealed that T&A is an effective therapeutic measure in such patients.
  American Journal of Otolaryngology 26(1):18-21. · 0.87 Impact Factor
• Article: [Hearing aid use and patient satisfaction].

  Orhan Kemal Kahveci, Murat Cem Miman, Erdoğan Okur, Abdullah Ayçiçek, Selçuk Sevinç, Ali Altuntaş
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  ABSTRACT: In this study, we assessed the hearing aid usage ratios and durations, patient satisfaction and the probable causes of disuse if they are not used. A questionnaire with 16 questions was applied to the patients who were prescribed hearing aids in our clinic between January 2007 and December 2009. A total of 517 patients were called by phone. Hundred and seventy-nine of the patients (75 females, 104 males; mean age 60±23 years; range 17 to 94 years) participated in the trial. Hearing aid usage ratios and patients' satisfaction were determined and the factors influencing usage were statistically investigated. Hundred and forty-two of the patients used their hearing aids regularly and 37 of the patients either used their aids rarely or never used them. The most common cause reported for disuse was the frequent noise coming from the hearing aid. Failure to explain the usage of the hearing aids to the patients and age over 70 years have a statistically significant negative effect on the duration of hearing aid use and patient satisfaction.
  Kulak burun bogaz ihtisas dergisi: KBB = Journal of ear, nose, and throat 21(3):117-21.