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ABSTRACT: Piebaldism is a rare genodermatosis in which depigmented skin areas are unresponsive to topical or light treatment. This article describes the importance of transplant techniques using noncultured melanocytes (minigrafting) in the treatment of piebaldism.
Anais brasileiros de dermatologia 06/2010; 85(3):384-8.
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ABSTRACT: The case of a 9-year-old girl with a history of blistering lesions restricted to the right side of her body is described. Several family members are also affected in a symmetrical fashion. Histological examination showed acantholysis similar to a 'dilapidated brick wall', corresponding to a rare presentation of mosaicism in Hailey-Hailey disease.
Anais brasileiros de dermatologia 12/2009; 84(6):680-1.
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ABSTRACT: A child was diagnosed with onychomycosis before he was 2 months of age; however, he had noticeable nail lesions from the second week of life.
Pediatric Dermatology 11/2009; 26(6):761-2. · 1.07 Impact Factor
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ABSTRACT: Although the radiographic characteristics of acute appendicitis have been well documented, the value of plain abdominal radiography has not been completely studied. Therefore, the purpose of this investigation was to establish the association and relevance of the image of fecal loading in the cecum detected by plain abdominal X-ray of patients with acute appendicitis.
One hundred and seventy consecutive patients of both sexes were admitted at the hospital with acute pain in the right flank. The hypothesis of appendicitis was confirmed by operation and histological examination. These patients were distributed into two groups: Group 1 (n=100), patients who had plain abdominal X-rays done a few hours before surgical treatment, and Group 2 (n=70), patients who had plain abdominal X-rays done before the surgical procedure and also the following day. All X-rays were taken from an anteroposterior view of the abdomen. Demographic data such as age, gender, and skin color (white, brown and black) and morphologic stages of acute appendicitis were also assessed.
Radiographic sign of fecal loading in the cecum was detected in 97 (97%) patients of Group 1 and in 68 (97.14%) patients of Group 2. This sign could not be detected any longer after surgery in 66 of the 68 positive cases. Sensitivity of this radiographic sign for acute appendicitis was 97.05%.
Radiographic image of fecal loading in the cecum of patients with abdominal pain is associated with acute appendicitis. The image usually becomes undetectable shortly after the appendix removal.
International journal of surgery (London, England) 03/2007; 5(1):11-6.
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ABSTRACT: Objective: The purpose of this investigation was to verify theimportance of the radiographic sign of fecal loading in the cecum forthe differential diagnosis of acute appendicitis. Methods: A total of470 consecutive patients of both sexes was admitted to hospital dueto acute abdomen and pain in the right flank and prospectively studied.The patients were divided as follows: Group 1 (n = 170) – diagnosedwith acute appendicitis and subdivided into two subgroups: Subgroup1A – (n = 100) – patients submitted to an abdominal radiographicstudy a few hours before surgical treatment, Subgroup 1B – (n = 70)– patients submitted to two radiographic studies of the abdomen, onebefore the surgical procedure and the other on the next day; Group 2(n = 100) – patients of both sexes with right nephrolithiasis submittedto an abdominal radiography during the episode of pain caused by thecalculus; Group 3 (n = 100) – women diagnosed with right acuteinflammatory pelvic disease that underwent an abdominal radiographicstudy during the pain crisis; Group 4 (n = 100) – patients of both sexeswho underwent surgery due to acute cholecystitis and were submittedto abdominal radiography during the pain episode that preceded thesurgical procedure. Results: The sign of fecal loading in the cecumwas present in 97 patients of Subgroup 1A, in 68 patients of Subgroup1B, in 19 patients of Group 2, in 12 patients of Group 3 and in 13patients of Group 4. During the postoperative period the radiographicsign disappeared in 66 of the 68 cases who presented the sign. Thesensitivity of the radiographic sign for acute appendicitis was 97.05%and specificity was 85.33%. The positive predictive value for acuteappendicitis was 78.94% and its negative predictive value was 98.08%.Conclusion: The radiographic image of fecal loading in the cecum isassociated with acute appendicitis. The image usually disappears soonafter the appendix is removed. This sign is uncommon in other acuteinflammatory diseases of the right side of the abdomen.
Einstein. 01/2007;
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ABSTRACT: Although the radiological features of acute appendicitis have been well documented, the value of plain radiography has not been fully appreciated. The aim of this study was to determine the frequency of the association of acute appendicitis with images of fecal loading in the cecum.
Plain abdominal radiographs of 400 patients operated upon for acute appendicitis (n = 100), acute cholecystitis (n = 100), right acute pelvic inflammatory disease (n = 100) and right nephrolithiasis (n = 100) were assessed. The presence of fecal loading was recorded and the sensitivity and specificity of this sign for acute appendicitis were calculated.
The presence of fecal loading in the cecum occurred in 97 patients with acute appendicitis, 13 patients with acute cholecystitis, 12 patients with acute inflammatory pelvic disease and 19 patients with nephrolithiasis. The sensitivity of this sign for appendicitis was 97% and its specificity to this disease was 85.3%. Its positive predictive value for appendicitis was 68.7%; however, its negative predictive value for appendicitis was 98.8%.
The present study suggests that the presence of radiological images of fecal loading in the cecum may be a useful sign of acute appendicitis, and the absence of this sign probably excludes this disease. This is the first description of fecal loading as a radiological sign for acute appendicitis.
World Journal of Gastroenterology 08/2005; 11(27):4230-2. · 2.47 Impact Factor
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ABSTRACT: To verify the relation between allergy and abortion or infertility.
A retrospective study was carried out by interviewing 250 women between 40 and 60 years of age, divided into two groups: Group 1 (n = 162): allergic women and Group 2 (n = 148): women with no record of allergy. Patients were randomly assessed at the Gynecology and Obstetric day care units of the "Hospital das Clínicas-UFMG". Women in both groups were identified according to their age and skin color. Previous abortion episodes and difficulty to become pregnant were recorded. Doubts related to these replies excluded the woman from this study. Results were compared using the chi-square test. Differences were considered significant for values corresponding to p < 0.05.
A higher incidence of difficulty to become pregnant was observed among the allergic patients in comparison to those non-allergic. In both groups, abortion and infertility were more frequent in Mulatto, followed by Caucasians and Black women. In 44.4% of the patients of group 1 the allergic manifestations worsened.
The presence of allergy seems to be related to a higher rate of infertility.
Revista da Associação Médica Brasileira 51(3):177-80. · 0.77 Impact Factor
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ABSTRACT: To assess the effect of surgical trauma on serum albumin concentration during the immediate postoperative period.
200 consecutive adult patients submitted to elective major surgeries (Group 1) and to medium size surgeries (Group 2) were identified according to gender, age and skin color. Blood samples for the determination of serum albumin concentration were obtained on the day preceding and the one following the surgical procedure. Pre- and postoperative albumin data were compared by the paired t test. The gender was compared by the Student t test. The skin color and the age were compared by the repeated measured one-way ANOVA and the Tukey-Kramer tests. The level of significance was set at P < 0.05.
There was a reduction in serum albumin in Group 1 (p < 0.0001) and Group 2 (p < 0.0001), with no difference between gender or skin colors for major surgeries. However, women showed a lower reduction than men in serum albumin in medium-sized surgeries. In medium-sized surgeries, black patients had the lowest reduction in albuminemia. The greater reduction in albuminemia occurred in patients older than 65 years old.
Medium-sized and majors operations provoked an acute reduction in albuminemia, which was more intense in aged white men.
Chirurgia (Bucharest, Romania: 1990) 103(1):39-43. · 0.38 Impact Factor