Ichiro Kawamura

Publications (13)19.66 Total impact

• Source

  Available from: Norio Ohmagari

  Article: Campylobacter showae bacteremia with cholangitis.

  Jun Suzuki, Tomoyo Sugiyama, Kenta Ito, Yoshiro Hadano, Ichiro Kawamura, Keiji Okinaka, Hanako Kurai, Kiyofumi Ohkusu, Norio Ohmagari
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  ABSTRACT: We report a case of Campylobacter showae bacteremia associated with cholangitis. A 71-year-old man with advanced bile duct cancer was admitted to our hospital because of cholangitis with shock, hypoglycemia, and impaired renal function. After replacement of the biliary drainage tube, pus was drained from the tube. Specimens for blood and bile cultures were obtained, and fluid resuscitation and antimicrobial treatment were then begun. Although anaerobic blood culture yielded small curved gram-negative rods, the isolate could not be identified by conventional identification methods. The isolate was identified as C. showae by 16S rRNA gene sequencing analysis. We consider here the pathogenicity of C. showae and the association of C. showae with cholangitis.
  Journal of Infection and Chemotherapy 11/2012; · 1.80 Impact Factor
• Source

  Available from: Norio Ohmagari

  Article: [A case of oral paracoccidioidomycosis suspected to be pharyngeal cancer].

  Hanako Kurai, Norio Ohmagari, Kenta Ito, Ichiro Kawamura, Jun Suzuki, Yoshiro Hadano, Masahiro Endo, Yoshiyuki Iida, Keiji Okinaka, Katsuhiko Kamei
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  ABSTRACT: Paracoccidioidomycosis is a fungal infection endemic to South American countries that affects the lungs, skin, and mucosae. Reports from Japan are limited by a long-term resident in South America. Some cases are incorrectly diagnosed because of a refractory buccal ulcer that resembles a malignant tumor. This is a disease that may not be correctly examined if we cannot suspect by a case history. We report the case of a Brazilian man who had a buccal ulcer with lung involvement, which mimicked pharyngeal cancer.
  Nippon Ishinkin Gakkai Zasshi 01/2012; 53(1):49-52.
• Article: Raoultella ornithinolytica Bacteremia in Cancer Patients: Report of Three Cases.

  Yoshiro Hadano, Mika Tsukahara, Kenta Ito, Jun Suzuki, Ichiro Kawamura, Hanako Kurai
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  ABSTRACT: Raoultella ornithinolytica is a Gram-negative aerobic bacillus reclassified in the new genus from the Klebsiella species based on new genetic approaches; however, human infections caused by R. ornithinolytica are rare. We herein report three cases of R. ornithinolytica bacteremia associated with biliary tract infections in cancer patients. R. ornithinolytica can be a causative pathogen of biliary tract infection in cancer patients.
  Internal Medicine 01/2012; 51(22):3193-5. · 0.94 Impact Factor
• Article: Moraxella osloensis: an unusual cause of central venous catheter infection in a cancer patient.

  Yoshiro Hadano, Kenta Ito, Jun Suzuki, Ichiro Kawamura, Hanako Kurai, Kiyofumi Ohkusu
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  ABSTRACT: Moraxella osloensis is a rare causative organism of infections in humans, with most cases reported in cancer patients. We report the case of a 67-year-old Japanese man with advanced cancer of the pancreatic head and multiple liver metastases who developed fever with chills. Blood culture was found to be positive for Gram-negative bacilli that were aerobic, oxidase-positive, and catalase-positive. M. osloensis was identified by 16 rRNA gene sequencing. Prompt control of the infection was achieved by treatment with cefepime for 14 days, without the need for removal of the central venous catheter.
  International Journal of General Medicine 01/2012; 5:875-7.
• Source

  Available from: Norio Ohmagari

  Article: [A case of pulmonary nocardiosis due to Nocardia cyriacigeorgica with prompt diagnosis by gram stain].

  Yoshiro Hadano, Norio Ohmagari, Jun Suzuki, Ichiro Kawamura, Keiji Okinaka, Hanako Kurai, Hiroyuki Tomioka, Yusuke Kinugasa, Kiyofumi Ohkusu
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  ABSTRACT: An 82-year-old woman with a past history of a colectomy for colon cancer was admitted to our hospital because of fever and cough. Her chest radiologic images on admission showed bilateral pulmonary infiltration, which suggested community-acquired pneumonia. However, the results of gram and acid-fast staining demonstrated branching acid-bacilli, which suggested pulmonary nocardiosis. We administered sulfamethoxazole-trimethoprim, and her condition and radiology findings promptly improved. Nocardia cyriacigeorgica was identified from her sputum. One of the nocardial isolates, formerly identified as Nocardia asteroides, has recently been reclassified as Nocardia cyriacigeorgica by the 16S rRNA gene amplification method. Pulmonary nocardiosis may be misidentified as "aspiration pneumonia", especially in elderly people. It is important for patients with community-acquired pneumonia to be evaluated with sputum gram staining for accurate diagnosis.
  Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 08/2011; 49(8):592-6.
• Article: Classification of odontoid destruction in patients with rheumatoid arthritis using reconstructed computed tomography: reference to vertical migration.

  Hirofumi Shimada, Masahiko Abematsu, Yasuhiro Ishido, Ichiro Kawamura, Hiroyuki Tominaga, Michihisa Zenmyo, Takuya Yamamoto, Eiji Taketomi, Setsuro Komiya, Kosei Ijiri
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  ABSTRACT: To reveal the factors that determine the natural course of subluxation of occipital-cervical lesions in rheumatoid arthritis (RA). The atlanto-axial region is one of the most common locations for lesions in RA. Some cases progress from reducible atlanto-axial subluxation (AAS) to irreducible vertical migration, while others continue to exhibit reducible AAS. No study has revealed the factors that determine the natural course of subluxation. We focus on the odontoid as a key structure of the progression of occipito-cervical lesions and investigated this region in patients with RA using reconstructive computed tomography (CT) images, and analyzed factors in association with CT findings. Fifty-eight patients with RA and 40 age-matched controls, all women, were studied. Associated factors, including C-reactive protein, erythrocyte sedimentation rate, steroid usage, and the severity of local osteoporosis, were analyzed as measurements in association with odontoid destruction. The destruction of odontoid and atlanto-odontoid joint were common in patients with RA. The more destruction observed in the odontoid process, the greater is the degree of progression of vertical migration. Local osteoporosis is a significant factor in odontoid destruction, based on a cortico-cancellous index of 42% in cases of grade III odontoid destruction. The odontoid process is a key structure in the progression of occipito-cervical lesions in patients with RA.
  The Journal of Rheumatology 03/2011; 38(5):863-7. · 3.69 Impact Factor
• Article: Recurrent vascular catheter-related bacteremia caused by Delftia acidovorans with different antimicrobial susceptibility profiles.

  Ichiro Kawamura, Tetsuya Yagi, Kazuhito Hatakeyama, Teruko Ohkura, Kiyofumi Ohkusu, Yoshiyuki Takahashi, Seiji Kojima, Yoshinori Hasegawa
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  ABSTRACT: An 11-year-old girl with metastatic neuroblastoma developed recurrent bacteremia during sustained neutropenia after autologous peripheral blood transplantation. All febrile episodes of bacteremia were caused by single Delftia acidovorans strain revealed by ERIC-PCR. This strain became resistant to broad-spectrum penicillins and cephalosporins through antibiotic treatments. Removal of the indwelling vascular catheter resulted in resolution of the infection. So far as we know, this is the first report of vascular catheter-related D. acidovorans bacteremia in Japan.
  Journal of Infection and Chemotherapy 02/2011; 17(1):111-3. · 1.80 Impact Factor
• Article: Pedicle subtraction osteotomy for adult tethered cord syndrome with lumbar canal stenosis: report of two cases.

  Ichiro Kawamura, Yasuhiro Ishido, Michihisa Zenmyo, Takuya Yamamoto, Yoichi Kagawa, Setsuro Komiya, Kosei Ijiri
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  ABSTRACT: Tethered cord syndrome with spinal lipoma is the most common form of occult spinal dysraphism. For the symptomatic patients, surgical treatment is recommended; however, there are many patients who have not been encouraged to seek medical attention until adulthood, since their symptoms are not severe enough to interfere with their daily activities. We performed pedicle subtraction osteotomy (PSO) to achieve indirect untethering and neural decompression in two senior patients with tethered cord syndrome, who showed deteriorating neurological condition due to coexisting lumbar canal stenosis. Here we report two patients (aged 56 and 60 years) who underwent PSO of L3 or L4. The pain disappeared and the bladder dysfunction recovered significantly after surgery. Complete bone union and untethering were achieved in both patients. PSO is an alternative surgical technique for senior patients with tethered cord syndrome caused by lumbosacral spinal lipoma, when the syndrome occurs along with lumbar canal stenosis.
  The International journal of neuroscience 11/2010; 120(11):735-7. · 0.86 Impact Factor
• Article: Ossification of the posterior longitudinal ligament in dizygotic twins with schizophrenia: a case report.

  Shunji Matsunaga, Hiroaki Koga, Naoya Kawabata, Ichiro Kawamura, Masaki Otusji, Takanori Imakiire, Setsuro Komiya
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  ABSTRACT: The pathogenesis of ossification of the posterior longitudinal ligaments (OPLL) has not been clarified. We here report dizygotic twin sisters with OPLL of the cervical spine and propose a new pathogenesis of OPLL. This is the first report of dizygotic twins with OPLL. The twins suffered from schizophrenia, which might be related to the pathogenesis of OPLL. In addition, we investigated the occurrence of OPLL in 30 patients with schizophrenia who had been admitted to a mental hospital. OPLL of the cervical spine was found in six (20%) of them, with an incidence almost five times higher than the incidence of OPLL among the general population in Japan. Schizophrenia may have a increased susceptibility to OPLL.
  Modern Rheumatology 02/2008; 18(3):277-80. · 1.58 Impact Factor
• Article: Repetitive behaviors in chronic schizophrenia: using the Japanese version of the Elgin Behavior Rating Scale (JEBRS).

  Yasuhiro Kaneda, Ichiro Kawamura, Akira Fujii, Tetsuro Ohmori
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  ABSTRACT: The main aim of this study was to test the reliability and value of the Japanese Elgin Behavior Rating Scale (JEBRS) with 92 schizophrenia patients. Cronbach's alpha for the JEBRS was 0.61. All inter-rater reliability coefficients were in the satisfactory range. The JEBRS had a high stability over time. Almost all of the correlations among the nine item scores and total score in the JEBRS were significant. The total score for nine repetitive behaviors in the JEBRS was positively correlated with positive and negative symptoms. This study showed that the JEBRS is a useful and reliable scale.
  International Journal of Neuroscience 07/2003; 113(6):879-90. · 0.97 Impact Factor
• Article: Serotonin syndrome - 'potential' role of the CYP2D6 genetic polymorphism in Asians.

  Yasuhiro Kaneda, Ichiro Kawamura, Akira Fujii, Tetsuro Ohmori
  The International Journal of Neuropsychopharmacology 04/2002; 5(1):105-6. · 4.58 Impact Factor
• Source

  Available from: nel.edu

  Article: Impact of a switch from typical to atypical antipsychotic drugs on quality of life and gonadal hormones in male patients with schizophrenia.

  Yasuhiro Kaneda, Ichiro Kawamura, Akira Fujii, Tetsuro Ohmori
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  ABSTRACT: We investigated the effects of a switch from typical to atypical antipsychotic drugs (olanzapine, n=8; perospirone, n=9; or quetiapine, n=13) on quality of life and hypothalamo-pituitary-gonadal axis hormones. The subjects were 30 male chronic schizophrenia inpatients. The assessment was done before and after the switch. After the switch, (i) scores of the Brief Psychiatric Rating Scale total and three factors (anxiety-depression, anergia, and thought disturbance) decreased, (ii) the overall severity score of the Drug Induced Extra-Pyramidal Symptoms Scale tended to decrease, (iii) prolactin decreased but gonadal hormones remained unchanged, and (iv) scores on all three subscales (psychosocial, motivation/energy, and symptoms/side effects) in the Japanese version of the Schizophrenia Quality of Life Scale (JSQLS) decreased. However, there were no significant group effects, or time-by-group interactions. In addition, score changes from baseline in psychosocial and motivation/energy subscales in the JSQLS were correlated with those in psychotic symptoms, particularly in the anxiety-depression factor. Moreover, responders had been taking lower doses of typical antipsychotic drugs, and had higher serum estradiol concentrations than non-responders before the switch. The study indicated that the switch to atypical antipsychotic drugs was effective in reducing elevated prolactin without affecting the gonadal hormones and in improving quality of life patients who had been treated with typical antipsychotic drugs.
  Neuro endocrinology letters 25(1-2):135-40. · 1.30 Impact Factor
• Article: Correlation between plasma homovanillic acid levels and the response to atypical antipsychotics in male patients with schizophrenia.

  Yasuhiro Kaneda, Ichiro Kawamura, Tetsuro Ohmori
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  ABSTRACT: The authors investigated the effects of atypical antipsychotic drugs-olanzapine, perospirone, and quetiapine-on plasma homovanillic acid (pHVA) in male patients with chronic schizophrenia. In this prospective, open-label study, the subjects were 30 inpatients who were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, criteria for schizophrenia. The authors switched patients from typical antipsychotic drugs to olanzapine, perospirone, or quetiapine. Each patient gave informed consent for the research. pHVA was assessed before and after switching medications. After the switch, the authors found a significant improvement in psychotic symptoms, nonsignificant improvement in extrapyramidal symptoms, and a nonsignificant reduction in pHVA. In addition, the baseline pHVA correlated positively with the score changes from baseline in the Brief Psychiatric Rating Scale (BPRS) total, positive, and negative symptoms in the group with a whole sample and in the olanzapine-treated group, and with the score changes in the BPRS total and positive symptoms in the quetiapine-treated group. Our findings indicated that the preswitching pHVA levels could be used to predict changes in the psychotic symptoms of male patients with chronic schizophrenia when switching to atypical antipsychotic drugs.
  Clinical Neuropharmacology 28(6):262-4. · 2.17 Impact Factor